DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1

Management of Extramedullary Leukemia as a Presentation of Acute Myeloid Leukemia

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Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse

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DNMT3A Mutational Status Affects the Results of Dose-Escalated Induction Therapy in Acute Myelogenous Leukemia

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Clinical and pathologic analysis of extramedullary tumors after hematopoietic stem cell transplantation

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Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

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Oncogenic roles of EMT-inducing transcription factors

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DNMT3A Arg882 mutation drives chronic myelomonocytic leukemia through disturbing gene expression/DNA methylation in hematopoietic cells

(2014) J. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A HIF-1 network reveals characteristics of epithelial-mesenchymal transition in acute promyelocytic leukemia

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Mutant DNMT3A clone evading chemotherapy and infiltrating central nervous system in a patient with molecularly good-risk acute myeloid leukemia

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Prevalence of extramedullary relapses is higher after allogeneic stem cell transplantation than after chemotherapy in adult patients with acute myeloid leukemia

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Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia

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Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia

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Overexpression of amyloid precursor protein in acute myeloid leukemia enhances extramedullary infiltration by MMP-2

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Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia

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Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1

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DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications

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How I treat extramedullary acute myeloid leukemia

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Cytogenetic profile of patients with acute myeloid leukemia and central nervous system disease

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Incidence and Prognostic Influence of DNMT3A Mutations in Acute Myeloid Leukemia

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The NPM1 wild-type OCI-AML2 and the NPM1-mutated OCI-AML3 cell lines carry DNMT3A mutations

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Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

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Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia

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Matrix Metalloproteinase-2 and -9 Secreted by Leukemic Cells Increase the Permeability of Blood-Brain Barrier by Disrupting Tight Junction Proteins

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Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression

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The essential roles of matrix metalloproteinase-2, membrane type 1 metalloproteinase and tissue inhibitor of metalloproteinase-2 in the invasive capacity of acute monocytic leukemia SHI-1 cells

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Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2

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