Design, synthesis and biological evaluation of novel pleuromutilin derivatives possessing 4-aminothiophenol linker as promising antibacterial agents

Design, synthesis, in vitro and in vivo evaluation against MRSA and molecular docking studies of novel pleuromutilin derivatives bearing 1, 3, 4-oxadiazole linker

(2021) Jie Liu et al.   BIOORGANIC CHEMISTRY

Applications of fluorine to the construction of bioisosteric elements for the purposes of novel drug discovery

(2021) Paul Richardson   Expert Opinion on Drug Discovery

Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker

(2020) Guang-Yu Zhang et al.   BIOORGANIC CHEMISTRY

Design, synthesis and biological activities of novel pleuromutilin derivatives with a substituted triazole moiety as potent antibacterial agents

(2020) Zhe Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of a Potent Adenine–Benzyltriazolo–Pleuromutilin Conjugate with Pronounced Antibacterial Activity against MRSA

(2020) Christoffer V. Heidtmann et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of novel pleuromutilin derivatives possessing acetamine phenyl linker

(2019) Zhen Jin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antibacterial activities of novel pleuromutilin derivatives bearing an aminothiophenol moiety

(2018) Zhao-Sheng Zhang et al.   Chemical Biology & Drug Design

Antibacterial properties and clinical potential of pleuromutilins

(2018) Olivia Goethe et al.   NATURAL PRODUCT REPORTS

The changing face of methicillin-resistant Staphylococcus aureus infections

(2017) Alistair T Leanord et al.   MEDICAL JOURNAL OF AUSTRALIA

Structure–Activity Relationship for the 4(3H)-Quinazolinone Antibacterials

(2016) Renee Bouley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pleuromutilins: Potent Drugs for Resistant Bugs—Mode of Action and Resistance

(2016) Susanne Paukner et al.   Cold Spring Harbor Perspectives in Medicine

Design, Synthesis, and Structure–Activity Relationship Studies of Novel Thioether Pleuromutilin Derivatives as Potent Antibacterial Agents

(2014) Chenyu Ling et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficient Antibacterial Agents: A Review of the Synthesis, Biological Evaluation and Mechanism of Pleuromutilin Derivatives

(2013) Ruofeng Shang et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Synthesis of New 7-Oxycoumarin Derivatives As Potent and Selective Monoamine Oxidase A Inhibitors

(2012) Omaima M. Abdelhafez et al.   JOURNAL OF MEDICINAL CHEMISTRY

Avogadro: an advanced semantic chemical editor, visualization, and analysis platform

(2012) Marcus D Hanwell et al.   Journal of Cheminformatics

Pleuromutilin and its Derivatives-The Lead Compounds for Novel Antibiotics

(2011) Y. -Z. Tang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Community-Associated Methicillin-Resistant Staphylococcus aureus: Epidemiology and Clinical Consequences of an Emerging Epidemic

(2010) M. Z. David et al.   CLINICAL MICROBIOLOGY REVIEWS

Community-associated meticillin-resistant Staphylococcus aureus

(2010) Frank R DeLeo et al.   LANCET

Waves of resistance: Staphylococcus aureus in the antibiotic era

(2009) Henry F. Chambers et al.   NATURE REVIEWS MICROBIOLOGY