Engineering mitochondrial uncoupler synergistic photodynamic nanoplatform to harness immunostimulatory pro-death autophagy/mitophagy

Nano-ultrasonic Contrast Agent for Chemoimmunotherapy of Breast Cancer by Immune Metabolism Reprogramming and Tumor Autophagy

(2022) Xupeng Yang et al.   ACS Nano

Enhancement of anti-PD-1/PD-L1 immunotherapy for osteosarcoma using an intelligent autophagy-controlling metal organic framework

(2022) Yu-Xiang Ge et al.   BIOMATERIALS

In Situ Self-Assembly Nanomicelle Microneedles for Enhanced Photoimmunotherapy via Autophagy Regulation Strategy

(2021) Minglong Chen et al.   ACS Nano

Engineering Chameleon Prodrug Nanovesicles to Increase Antigen Presentation and Inhibit PD‐L1 Expression for Circumventing Immune Resistance of Cancer

(2021) Fengqi Zhou et al.   ADVANCED MATERIALS

Heparin-Coated Photosensitive Metal–Organic Frameworks as Drug Delivery Nanoplatforms of Autophagy Inhibitors for Sensitized Photodynamic Therapy against Breast Cancer

(2021) Quanwei Sun et al.   ACS Applied Materials & Interfaces

Mitochondrial-targeting nanoprodrugs to mutually reinforce metabolic inhibition and autophagy for combating resistant cancer

(2021) Min Sun et al.   BIOMATERIALS

Engineering of Upconverted Metal–Organic Frameworks for Near-Infrared Light-Triggered Combinational Photodynamic/Chemo-/Immunotherapy against Hypoxic Tumors

(2020) Yulei Shao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fusiform-Like Copper(II)-Based Metal–Organic Framework through Relief Hypoxia and GSH-Depletion Co-Enhanced Starvation and Chemodynamic Synergetic Cancer Therapy

(2020) Zhao Wang et al.   ACS Applied Materials & Interfaces

Icaritin Exacerbates Mitophagy and Synergizes with Doxorubicin to Induce Immunogenic Cell Death in Hepatocellular Carcinoma

(2020) Zhuo Yu et al.   ACS Nano

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

(2020) Keisuke Yamamoto et al.   NATURE

3-Bromopyruvate-Conjugated Nanoplatform-Induced Pro-Death Autophagy for Enhanced Photodynamic Therapy against Hypoxic Tumor

(2020) Yongyan Deng et al.   ACS Nano

Site-specific MOF-based immunotherapeutic nanoplatforms via synergistic tumor cells-targeted treatment and dendritic cells-targeted immunomodulation

(2020) Huiyuan Zhang et al.   BIOMATERIALS

Corn-like Au/Ag nanorod-mediated NIR-II photothermal/photodynamic therapy potentiates immune checkpoint antibody efficacy by reprogramming the cold tumor microenvironment

(2020) Liangjie Jin et al.   BIOMATERIALS

An ATP-Regulated Ion Transport Nanosystem for Homeostatic Perturbation Therapy and Sensitizing Photodynamic Therapy by Autophagy Inhibition of Tumors

(2019) Shuang-Shuang Wan et al.   ACS Central Science

Biomimetic Metal-Organic Framework Nanoparticles for Cooperatively Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy

(2019) Huan Min et al.   ADVANCED MATERIALS

Organic Photodynamic Nanoinhibitor for Synergistic Cancer Therapy

(2019) Yuyan Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy

(2019) Marc P. M. Soutar et al.   Autophagy

Renal-Clearable Porphyrinic Metal–Organic Framework Nanodots for Enhanced Photodynamic Therapy

(2019) Huan Wang et al.   ACS Nano

Pro-Death or Pro-Survival: Contrasting Paradigms on Nanomaterial-Induced Autophagy and Exploitations for Cancer Therapy

(2019) Yunjiao Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Mitochondria-acting nanomicelles for destruction of cancer cells via excessive mitophagy/autophagy-driven lethal energy depletion and phototherapy

(2019) Ya-Xuan Zhu et al.   BIOMATERIALS

Innovative Strategies for Hypoxic-Tumor Photodynamic Therapy

(2018) Xingshu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2 -Based Nanoagent to Enhance Chemodynamic Therapy

(2018) Li-Sen Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomimetic O 2 -Evolving metal-organic framework nanoplatform for highly efficient photodynamic therapy against hypoxic tumor

(2018) Shutao Gao et al.   BIOMATERIALS

Inhibition of autophagy sensitizes cancer cells to Photofrin-based photodynamic therapy

(2018) Antoni Domagala et al.   BMC CANCER

Nitric oxide as an all-rounder for enhanced photodynamic therapy: Hypoxia relief, glutathione depletion and reactive nitrogen species generation

(2018) Yongyan Deng et al.   BIOMATERIALS

Autophagy inhibitor enhance ZnPc/BSA nanoparticle induced photodynamic therapy by suppressing PD-L1 expression in osteosarcoma immunotherapy

(2018) Wei Yu et al.   BIOMATERIALS

Carbon-Dot-Decorated Carbon Nitride Nanoparticles for Enhanced Photodynamic Therapy against Hypoxic Tumor via Water Splitting

(2016) Di-Wei Zheng et al.   ACS Nano

Intelligent Albumin-MnO2Nanoparticles as pH-/H2O2-Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy

(2016) Qian Chen et al.   ADVANCED MATERIALS

Size-Controlled Synthesis of Porphyrinic Metal–Organic Framework and Functionalization for Targeted Photodynamic Therapy

(2016) Jihye Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy

(2016) Lorenzo Galluzzi et al.   Nature Reviews Clinical Oncology

Nanoparticles in Photodynamic Therapy

(2015) Sasidharan Swarnalatha Lucky et al.   CHEMICAL REVIEWS

Danger signalling during cancer cell death: origins, plasticity and regulation

(2013) A D Garg et al.   CELL DEATH AND DIFFERENTIATION

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Principles and Current Strategies for Targeting Autophagy for Cancer Treatment

(2011) R. K. Amaravadi et al.   CLINICAL CANCER RESEARCH

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY