Modulation of α-Synuclein Aggregation In Vitro by a DNA Aptamer

Non-polyphenolic natural inhibitors of amyloid aggregation

(2020) Liang Ma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Mechanisms of aggregation and fibril formation of the amyloidogenic N-terminal fragment of apolipoprotein A-I

(2019) Chiharu Mizuguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomal DNA aptamer targeting α-synuclein aggregates reduced neuropathological deficits in a mouse Parkinson’s Disease model

(2019) Xiaoxi Ren et al.   Molecular Therapy-Nucleic Acids

DNA Facilitates Oligomerization and Prevents Aggregation via DNA Networks

(2019) Theodore J. Litberg et al.   BIOPHYSICAL JOURNAL

Novel DNA Aptamers for Parkinson’s Disease Treatment Inhibit α-Synuclein Aggregation and Facilitate its Degradation

(2018) Yuan Zheng et al.   Molecular Therapy-Nucleic Acids

Aptamer-based lateral flow assay for point of care cortisol detection in sweat

(2018) Shima Dalirirad et al.   SENSORS AND ACTUATORS B-CHEMICAL

Pre-aggregation kinetics and intermediates of α-synuclein monitored by the ESIPT probe 7MFE

(2017) Jonathan A. Fauerbach et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Challenges with osmolytes as inhibitors of protein aggregation: Can nucleic acid aptamers provide an answer?

(2017) Kinjal A. Patel et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Aptamer-based point-of-care diagnostic platforms

(2017) Abhijeet Dhiman et al.   SENSORS AND ACTUATORS B-CHEMICAL

Inhibitory RNA Aptamers of Tau Oligomerization and Their Neuroprotective Roles against Proteotoxic Stress

(2016) Ji Hyeon Kim et al.   MOLECULAR PHARMACEUTICS

Estimation of the lag time in a subsequent monomer addition model for fibril elongation

(2016) Suzanne K. Shoffner et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers In Vitro and in a Yeast Model of Huntington's Disease

(2015) Rajeev K Chaudhary et al.   MOLECULAR THERAPY

Polyphenols as Therapeutic Molecules in Alzheimer’s Disease Through Modulating Amyloid Pathways

(2014) Johant Lakey-Beitia et al.   MOLECULAR NEUROBIOLOGY

Modeling of chemical inhibition from amyloid protein aggregation kinetics

(2014) José Antonio Vázquez   BMC Pharmacology & Toxicology

Selection of DNA Aptamers That Recognize α-Synuclein Oligomers Using a Competitive Screening Method

(2012) Kaori Tsukakoshi et al.   ANALYTICAL CHEMISTRY

The many faces of α-synuclein: from structure and toxicity to therapeutic target

(2012) Hilal A. Lashuel et al.   NATURE REVIEWS NEUROSCIENCE

Protein Instability and Immunogenicity: Roadblocks to Clinical Application of Injectable Protein Delivery Systems for Sustained Release

(2011) Wim Jiskoot et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

RNA aptamers selected against amyloid β-peptide (Aβ) inhibit the aggregation of Aβ

(2009) Tsuyoshi Takahashi et al.   Molecular BioSystems

α-Synuclein aggregation variable temperature and variable pH kinetic data: A re-analysis using the Finke–Watzky 2-step model of nucleation and autocatalytic growth

(2008) Aimee M. Morris et al.   BIOPHYSICAL CHEMISTRY

Phosphorylation at Ser-129 but Not the Phosphomimics S129E/D Inhibits the Fibrillation of α-Synuclein

(2008) Katerina E. Paleologou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY