Torsional Strain‐Independent Catalytic Enantioselective Synthesis of Biaryl Atropisomers

Copper-Catalyzed Asymmetric Ring-Opening Reaction of Cyclic Diaryliodonium Salts with Imides

(2022) Fu Cheng et al.   ORGANIC LETTERS

Transition Metal-Catalyzed Biaryl Atropisomer Synthesis via a Torsional Strain Promoted Ring-Opening Reaction

(2022) Xue Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Diastereo‐ and Enantioselective Silver‐Catalyzed [3+3] Cycloaddition and Kinetic Resolution of Azomethine Imines with Activated Isocyanides

(2022) Ling‐Fei Tao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atroposelective Construction of Nine‐Membered Carbonate Bridged Biaryls

(2022) Shiqi Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective alkylative cross-coupling of unactivated aromatic C–O electrophiles

(2022) Zishuo Zhang et al.   Nature Communications

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Construction of Axial Chirality and Silicon-Stereogenic Center via Rh-Catalyzed Asymmetric Ring-Opening of Silafluorenes

(2021) Xiufen Bi et al.   ORGANIC LETTERS

Palladium-Catalyzed Enantioselective 7-exo-Trig Carbopalladation/Carbonylation: Cascade Reactions To Achieve Atropisomeric Dibenzo[b,d]azepin-6-ones

(2021) Huaanzi Hu et al.   ORGANIC LETTERS

Carbene‐Catalyzed Asymmetric Construction of Atropisomers

(2021) Runjiang Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Atropisomers by Transition-Metal-Catalyzed Asymmetric C–H Functionalization Reactions

(2021) Chen-Xu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Atroposelective Dynamic Kinetic Resolution of Biaryl Lactones with Activated Isocyanides

(2021) Linghui Qian et al.   ORGANIC LETTERS

Recent advances in the chemistry and applications of N-heterocyclic carbenes

(2021) Peter Bellotti et al.   Nature Reviews Chemistry

Nickel-Catalyzed Enantioselective Arylative Activation of Aromatic C–O Bond

(2021) Jintong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic asymmetric N-sulfonyl amide C-N bond activation to access axially chiral biaryl amino acids

(2020) Guanjie Wang et al.   Nature Communications

Atroposelective Ring Opening of Cyclic Diaryliodonium Salts with Bulky Anilines Controlled by a Chiral Cobalt(III) Anion

(2020) Zhenhua Gu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Fluorescent Recognition of Free Amino Acids:  Challenges and Opportunities

(2020) Lin Pu   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Reductive Amination/Ring-Closing Cascade: Direct Synthesis of Enantioenriched Biaryl-Bridged NH Lactams

(2020) Yao Zhang et al.   ORGANIC LETTERS

Recent Developments on Catalytic Enantioselective Isocyanide‐Based Reactions: Beyond Passerini and Ugi Multicomponent Reactions

(2020) Yun-Lin Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Dynamic Kinetic Resolutions in Tandem to Construct Two-Axis Terphenyl Atropisomers

(2020) Omar M. Beleh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic asymmetric C–Si bond activation via torsional strain-promoted Rh-catalyzed aryl-Narasaka acylation

(2020) Jia Feng et al.   Nature Communications

Diols Activation via Cu/Borinic Acids Synergistic Catalysis in Atroposelective Ring‐Opening of Cyclic Diaryliodoniums

(2020) Zhenhua Gu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hexafluoroisopropanol-Enabled Copper-Catalyzed Asymmetric Halogenation of Cyclic Diaryliodoniums for the Synthesis of Axially Chiral 2,2′-Dihalobiaryls

(2020) Jie Ke et al.   ORGANIC LETTERS

Synthesis of Bridged Biaryl Atropisomers via Sequential Cu- and Pd-Catalyzed Asymmetric Ring Opening and Cyclization

(2019) Xiaoping Xue et al.   ORGANIC LETTERS

Enantioselective Synthesis of Axially Chiral Biaryls via Cu-Catalyzed Acyloxylation of Cyclic Diaryliodonium Salts

(2019) Kai Zhu et al.   ACS Catalysis

Enantioselective Carbon-Carbon Bond Cleavage for Biaryl Atropisomers Synthesis

(2019) Ruixian Deng et al.   Chem

CuH-Catalyzed Atropoenantioselective Reduction of Bringmann’s Lactones via Dynamic Kinetic Resolution

(2019) Le’an Hu et al.   ORGANIC LETTERS

Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade

(2019) Shenci Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Ring-Opening/Oxidative Phosphorylation and P-Transfer Reaction of Cyclic Diaryliodoniums

(2019) Longhui Duan et al.   ACS Catalysis

Axially Chiral Dibenzazepinones via a Pd(0)-Catalyzed Atropo-enantioselective C-H Arylation

(2018) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective arene formation

(2018) Achim Link et al.   CHEMICAL SOCIETY REVIEWS

Atropisomerism in medicinal chemistry: challenges and opportunities

(2018) Sean T Toenjes et al.   Future Medicinal Chemistry

Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann’s Lactones with Molecular H2

(2018) Gen-Qiang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic kinetic resolution of biaryl atropisomers by chiral dialkylaminopyridine catalysts

(2018) Gaoyuan Ma et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enhanced Reactivity by Torsional Strain of Cyclic Diaryliodonium in Cu-Catalyzed Enantioselective Ring-Opening Reaction

(2018) Kun Zhao et al.   Chem

Catalytic Enantioselective Tautomerization of Metastable Enamines

(2017) Jingjing Liu et al.   ORGANIC LETTERS

Auto-Tandem Catalysis: Activation of Multiple, Mechanistically Distinct Process by a Single Catalyst

(2016) Jason E. Camp   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Dynamic Kinetic Resolution of Biaryl Lactones via a Chiral Bifunctional Amine Thiourea-Catalyzed Highly Atropo-enantioselective Transesterification

(2016) Chenguang Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

A twist of nature – the significance of atropisomers in biological systems

(2015) Jamie E. Smyth et al.   NATURAL PRODUCT REPORTS

Highly Diastereo- and Enantioselective Silver-Catalyzed Double [3+2] Cyclization of α-Imino Esters with Isocyanoacetate

(2014) Pan-Lin Shao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Enantioselective CH Arylation Strategy for Functionalized Dibenzazepinones with Quaternary Stereocenters

(2013) Tanguy Saget et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

A New Family of Cinchona-Derived Amino Phosphine Precatalysts: Application to the Highly Enantio- and Diastereoselective Silver-Catalyzed Isocyanoacetate Aldol Reaction

(2011) Filippo Sladojevich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Isocyanoacetate Derivatives: Synthesis, Reactivity, and Application

(2010) Anton V. Gulevich et al.   CHEMICAL REVIEWS

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Auto-Tandem Catalysis: A Single Catalyst Activating Mechanistically Distinct Reactions in a Single Reactor

(2009) Naoya Shindoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions

(2008) Masahiro Terada   CHEMICAL COMMUNICATIONS

Catalyticatropo-Enantioselective Reduction of Biaryl Lactones to Axially Chiral Biaryl Compounds

(2008) Tomoko Ashizawa et al.   ORGANIC LETTERS