Article
Chemistry, Analytical
Nuo Zhang, Dongquan Leng, Yaoguang Wang, Zhuangzhuang Ru, Guanhui Zhao, Yueyun Li, Daopeng Zhang, Qin Wei
Summary: A novel dual mode detection system has been developed to achieve simultaneous and reliable detection of neuron specific enolase using split-type photoelectrochemical and visual immunoassay, providing important application prospects.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Nuo Zhang, Yueyuan Li, Guanhui Zhao, Jinhui Feng, Yueyun Li, Yaoguang Wang, Daopeng Zhang, Qin Wei
Summary: A novel photoelectrochemical immunoassay was developed for the detection of Neuron specific enolase (NSE) using SnO2/Mn0.05Cd0.95S composites as substrate materials and CoSnO3 nanobox as labeled secondary antibody. The immunoassay demonstrated high sensitivity and good stability for NSE detection.
Article
Biochemistry & Molecular Biology
Xiaodong Yu, Xinjin Li, Shuan Zhang, Yilei Jia, Zhen Xu, Xiangye Li, Zhiwei Chen, Yueyun Li
Summary: A sandwich-type electrochemical immunosensor was developed in this study for the quantitative detection of neuron-specific enolase (NSE) in small cell lung cancer diagnosis. The use of AuPt NSNs and Au/CuxO@CeO2 as substrates showed enhanced performance in terms of electron conduction, immobilization capacity, catalytic activity, and signal amplification, resulting in sensitive and effective detection of NSE. The designed immunosensor exhibited a broad linear range, low detection limit, and satisfactory sensitivity, selectivity, and stability.
BIOELECTROCHEMISTRY
(2021)
Article
Engineering, Environmental
Yu Zhang, Mingfu Gong, Xiang Li, Hongyu Liu, Penghui Liang, Shuhua Cui, Liang Zhang, Chunyu Zhou, Tao Sun, Maosheng Zhang, Cong-Ying Wen, Jingbin Zeng
Summary: In this study, an ultrasensitive colorimetry for Salmonella typhimurium detection was developed using multifunctional Au-Fe3O4 dumbbell-like nanoparticles (DBNPs), which showed excellent detection capability, efficient capture capability, and good stability and specificity.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Analytical
Pei Miao, Mengjiao Hao, Chengfang Li, Wenshou Wang, Shenguang Ge, Xiaofeng Yang, Bing Geng, Biyan Ding, Jing Zhang, Mei Yan
Summary: A split-type photoelectrochemical (PEC) sensor based on Ti3C2/MgIn2S4 has been proposed for sensitive and accurate detection of miRNA-21. The Ti3C2/MgIn2S4 heterojunction effectively separates photogenerated electrons and holes, while a multifunctional PCN-224 nanocontainer amplifies the signal. The sensor achieved enhanced photocurrent response by releasing trapped glucose and utilizing glucose oxidase to generate hydrogen peroxide.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Delun Zheng, Zengyao Zheng, Jianying Yang, Yanping Xu, Kwan-Ming Ng, Linjia Huang, Yaowen Chen, Wenhua Gao
Summary: In this study, a CuO/NCDs@Au heterostructured nanocomposite was successfully prepared, which exhibited improved photocurrent response due to the porous hollow structure. The material showed excellent photoelectric properties and could be used to fabricate a PEC sensing platform with high sensitivity and wide linear range.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Dan Long, Yupeng Tu, Yaqin Chai, Ruo Yuan
Summary: The newly designed photoelectrochemical assay for DNA determination demonstrated improved photoelectric conversion efficiency and photocurrent, offering potential for detecting a wide range of biomarkers with high sensitivity.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Zhongnan Huang, Sunxing Yu, Meili Jian, Zhimin Weng, Haohua Deng, Huaping Peng, Wei Chen
Summary: This study presents an electrochemiluminescence (ECL) platform based on gold nanoclusters for ultrasensitive detection of glutathione (GSH) and adenosine triphosphate (ATP). The platform exhibits high sensitivity, wide dynamic range, and strong anti-interference properties, showing great potential in the detection of GSH-related substances.
ANALYTICAL CHEMISTRY
(2022)
Article
Biophysics
Hui Wang, Hanyu Wang, Yuyang Li, Huan Wang, Xiang Ren, Qin Wei, Dan Wu
Summary: In this study, a photoelectrochemical immunosensor was developed for the detection of neuron-specific enolase (NSE). The use of ITO/BiVO4/BiOI/Ag2S as the photoanode and ITO/CuInS2 as the photocathode improved the photocurrent response and reduced the detection limit. The constructed immunosensor exhibited excellent linear relationship, stability, reproducibility, and specificity, providing a promising approach for the detection of other molecules.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biophysics
Yong Zhang, Deling Liu, Yingying Zhang, Yanrong Qian, Chenchen Li, Zhengfang Qu, Rui Xu, Qin Wei
Summary: A novel signal-enhanced photoelectrochemical immunoassay technique for detecting NSE was proposed by doping Ce and Ag to improve the PEC performance of Sb2WO6, achieving sensitive detection of NSE with high sensitivity and stability.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Analytical
Dawei Fan, Jing Luo, Zhengxing Gong, Huan Wang, Hongmin Ma, Dan Wu, Qin Wei, Huangxian Ju
Summary: In this paper, a novel photoelectrochemical immunosensor based on a ZnO/CdSe semiconductor composite material was developed for the super-sensitive and quantitative detection of neuron-specific enolase (NSE). The antifouling interface composed of polyacrylic acid (PAA) and polyethylene glycol (PEG) effectively prevented non-specific protein adsorption. Ascorbic acid (AA) served as an electron donor, enhancing the stability and intensity of photocurrent by scavenging photogenerated holes. The PEC antifouling immunosensor exhibited a wide linear range (0.10 pg mL-1-100 ng mL-1) and a low detection limit (34 fg mL-1), making it a potential tool for clinical diagnosis of small cell lung cancer.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Si Dai, Hui Huang, Shihan Liu, Wenfang Deng, Yueming Tan, Qingji Xie
Summary: In this study, Au nanoclusters (AuNCs) were used as both photosensitizers and peroxidase mimics for sensitive PEC sensing of Hg2+. The AuNCs improved the PEC activity of WO3 nanorods as photosensitizers, and catalyzed precipitate formation on the photoelectrode as peroxidase mimics. The presence of Hg2+ inhibited the AuNCs-catalyzed precipitate formation, leading to an increase in the photocurrent of the photoelectrode for the PEC detection of Hg2+.
Article
Chemistry, Analytical
Hongchao Geng, Xiaoxu Chen, Leilei Sun, Yan Qiao, Jie Song, Sisi Shi, Qingyun Cai
Summary: A highly selective and sensitive photoelectrochemical sensing platform was developed for kanamycin assay based on sandwich-structured nanowires, showing excellent detection performance and high selectivity.
ANALYTICA CHIMICA ACTA
(2021)
Article
Biophysics
Haihan Yu, Xiaoran Tan, Shubo Sun, Lina Zhang, Chaomin Gao, Shenguang Ge
Summary: Novel one-dimensional SnO2 nanotubes on paper with high photoelectric conversion efficiency were developed by using a template consumption strategy. The incorporation of Sn self-doping and visible light response enhanced the photocurrent signal, leading to ultrasensitive detection of alpha fetoprotein in paper-based photoelectrochemical biosensor. Overall, an innovative strategy for developing novel photoactive materials for paper-based PEC bioanalysis was demonstrated.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Yu Du, Siqi Yu, Huangxian Ju
Summary: A quenching-typed electrochemiluminescence immunosensing method was proposed for protein detection using tungsten-based polyoxometalate nanoclusters and free radicals. The method demonstrated excellent detection limit and detectable range.
ANALYTICA CHIMICA ACTA
(2022)