Multiassay Profiling of a Focused Small Molecule Library Reveals Predictive Bidirectional Modulation of the lncRNA MALAT1 Triplex Stability In Vitro

Quantitative Structure–Activity Relationship (QSAR) Study Predicts Small-Molecule Binding to RNA Structure

(2022) Zhengguo Cai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Unraveling the structure and biological functions of RNA triple helices

(2020) Jessica A. Brown   Wiley Interdisciplinary Reviews-RNA

Regulation of MALAT1 triple helix stability and in vitro degradation by diphenylfurans

(2020) Anita Donlic et al.   NUCLEIC ACIDS RESEARCH

Selective small molecule targeting of a triple helix encoded by the long non-coding RNA, MALAT1

(2019) Fardokht A Abulwerdi et al.   ACS Chemical Biology

New Insights into Long Non-Coding RNA MALAT1 in Cancer and Metastasis

(2019) Yutong Sun et al.   Cancers

Improving data splitting for classification applications in spectrochemical analyses employing a random-mutation Kennard-Stone algorithm approach

(2019) Camilo L M Morais et al.   BIOINFORMATICS

Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space

(2019) Noreen F. Rizvi et al.   SLAS Discovery

The role of lncRNA MALAT1 in cardiovascular disease

(2019) Youyou Yan et al.   IUBMB LIFE

Photoresponsive azo-combretastatin A-4 analogues

(2018) Shiva K. Rastogi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches

(2018) Nicola Amodio et al.   Journal of Hematology & Oncology

Principles for targeting RNA with drug-like small molecules

(2018) Katherine Deigan Warner et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes

(2018) Amparo Garcia-Lopez et al.   Nature Communications

Discovery of Small Molecule Ligands for MALAT1 by Tuning an RNA-Binding Scaffold

(2018) Anita Donlic et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice

(2018) Indu G. Rajapaksha et al.   Scientific Reports

Advances in the Development of Shape Similarity Methods and Their Application in Drug Discovery

(2018) Ashutosh Kumar et al.   Frontiers in Chemistry

Small molecules that target group II introns are potent antifungal agents

(2018) Olga Fedorova et al.   Nature Chemical Biology

Finely tuned conformational dynamics regulate the protective function of the lncRNA MALAT1 triple helix

(2018) Abeer A Ageeli et al.   NUCLEIC ACIDS RESEARCH

Myriad Triple-Helix-Forming Structures in the Transposable Element RNAs of Plants and Fungi

(2016) Kazimierz T. Tycowski et al.   Cell Reports

Differential Scanning Fluorimetry for Monitoring RNA Stability

(2015) Robert Silvers et al.   CHEMBIOCHEM

Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix

(2014) Jessica A Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The emerging role of triple helices in RNA biology

(2013) Nicholas K. Conrad   Wiley Interdisciplinary Reviews-RNA

A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails

(2012) J. E. Wilusz et al.   GENES & DEVELOPMENT

Formation of triple-helical structures by the 3'-end sequences of MALAT1 and MEN  noncoding RNAs

(2012) J. A. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bovine Pancreatic Ribonuclease: Fifty Years of the First Enzymatic Reaction Mechanism

(2011) Claudi M. Cuchillo et al.   BIOCHEMISTRY

Structure–activity studies of RNA-binding oxazolidinone derivatives

(2011) Iwona Maciagiewicz et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Advances in computational methods to predict the biological activity of compounds

(2010) Chanin Nantasenamat et al.   Expert Opinion on Drug Discovery

A Role for Water Molecules in DNA−Ligand Minor Groove Recognition

(2008) Binh Nguyen et al.   ACCOUNTS OF CHEMICAL RESEARCH