Enantioselective Synthesis of Atropisomers via Vinylidene ortho-Quinone Methides (VQMs)

An Isolable Vinylidene ortho‐Quinone Methide: Synthesis, Structure and Reactivity

(2022) Hong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic atroposelective construction of axially chiral nonsymmetric biaryltriols and their applications in asymmetric synthesis and heavy metal ion detection

(2022) Shiqi Jia et al.   Organic Chemistry Frontiers

Atroposelective Construction of Nine‐Membered Carbonate Bridged Biaryls

(2022) Shiqi Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Dearomatizing Hetero-Diels–Alder Reaction of Nonactivated Arenes

(2022) Kai Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Azide–Alkyne Cycloaddition with Ir(I)/Squaramide Cooperative Catalysis: Atroposelective Synthesis of Axially Chiral Aryltriazoles

(2022) Xue Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic atroposelective construction of axially chiral N, N- and N, S-1,2-azoles through novel ring formation approach

(2022) Yu Chang et al.   Nature Communications

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Catalyst Control over Twofold and Higher-Order Stereogenicity by Atroposelective Arene Formation

(2021) Tanno A. Schmidt et al.   ACCOUNTS OF CHEMICAL RESEARCH

Organocatalytic Enantioselective Construction of Chiral Azepine Skeleton Bearing Multiple‐Stereogenic Elements

(2021) Shengli Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Axially Chiral Biaryls by Diels–Alder/Retro-Diels–Alder Reaction of 2-Pyrones with Alkynes

(2021) Meng-Meng Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Urea group-directed organocatalytic asymmetric versatile dihalogenation of alkenes and alkynes

(2021) San Wu et al.   Nature Catalysis

Diversity-Oriented Enantioselective Construction of Atropisomeric Heterobiaryls and N -Aryl Indoles via Vinylidene Ortho -Quinone Methides

(2021) Da Xu et al.   CCS Chemistry

Enantioselective Construction of Axially Chiral Amino Sulfide Vinyl Arenes by Chiral Sulfide-Catalyzed Electrophilic Carbothiolation of Alkynes

(2020) Yaoyu Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of N–C Axially Chiral Compounds by Cu‐Catalyzed Atroposelective Aryl Amination

(2020) Johanna Frey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Iodosuccinimide-Mediated Dimerization of 2-Alkynylnaphthols: A Highly Diastereoselective Construction of Bridged Polycyclic Compounds via Vinylidene ortho-Quinone Methide Intermediate

(2020) Yu Tan et al.   ORGANIC LETTERS

Construction of Axially Chiral Compounds via Central‐to‐Axial Chirality Conversion

(2020) Hui Yang et al.   Chemistry-An Asian Journal

Design and Atroposelective Construction of IAN analogues by Organocatalytic Asymmetric Heteroannulation of Alkynes

(2020) Lei Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Naphthyl-C2-Indole as Scaffold for Phosphine Organocatalysis: Application in Asymmetric Formal [4 + 2] Cycloaddition Reactions

(2020) Tingting He et al.   ORGANIC LETTERS

Vinylidene ortho-Quinone Methides: Unique Chiral Reaction Intermediates in Catalytic Asymmetric Synthesis

(2019) Sachie Arae et al.   CHIMIA

NHC-catalyzed atropoenantioselective synthesis of axially chiral biaryl amino alcohols via a cooperative strategy

(2019) Gongming Yang et al.   Nature Communications

Rational design, enantioselective synthesis and catalytic applications of axially chiral EBINOLs

(2019) Yong-Bin Wang et al.   Nature Catalysis

Organocatalytic Asymmetric Annulation of ortho -Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-indoles

(2019) Lei Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Control of Both Helical and Axial Stereogenic Elements though an Organocatalytic Approach

(2019) Shiqi Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isothiazoles in the Design and Synthesis of Biologically Active Substances and Ligands for Metal Complexes

(2019) Alexey V. Kletskov et al.   SYNTHESIS-STUTTGART

From Prochiral N-Heterocyclic Carbenes to Optically Pure Metal Complexes: New Opportunities in Asymmetric Catalysis

(2019) Lingyu Kong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Atroposelective Intramolecular [4+2] Cycloaddition: Synthesis of Axially Chiral Heterobiaryls

(2018) Yidong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective arene formation

(2018) Achim Link et al.   CHEMICAL SOCIETY REVIEWS

Organocatalytic Enantioselective Construction of Axially Chiral Sulfone-Containing Styrenes

(2018) Shiqi Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent developments in azole compounds as antitubercular agent

(2018) Girish Kumar Gupta et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Asymmetric Synthesis of Axially Chiral Benzocarbazole Derivatives Based on Catalytic Enantioselective Hydroarylation of Alkynes

(2018) Sachie Arae et al.   ORGANIC LETTERS

Asymmetric Mannich Reaction and Construction of Axially Chiral Sulfone-Containing Styrenes in One Pot from α-Amido Sulfones Based on the Waste–Reuse Strategy

(2018) Dongmei Li et al.   ORGANIC LETTERS

Organocatalytic Asymmetric One-Step Desymmetrizing Dearomatization Reaction of Indoles: Development and Bioactivity Evaluation

(2018) Lei Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Construction of Vicinal Diaxial Styrenes and Multiaxis System via Organocatalysis

(2018) Yu Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric One-Pot Construction of Three Stereogenic Elements: Chiral Carbon Center, Stereoisomeric Alkenes, and Chirality of Axial Styrenes

(2018) Anqi Huang et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Atroposelective Construction of Axially Chiral 1,4-Distyrene 2,3-Naphthalene Diols

(2018) Shan Li et al.   ORGANIC LETTERS

Indole-fused azepines and analogues as anticancer lead molecules: Privileged findings and future directions

(2017) Ashok K. Singh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Stereoselective Intramolecular Dearomatizative [4+2] Cycloaddition of Linked Ethynylnaphthol-Benzofuran Systems

(2017) Shota Beppu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy

(2017) Vivek S. Raut et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic asymmetric arylation of indoles enabled by azo groups

(2017) Liang-Wen Qi et al.   Nature Chemistry

Organocatalytic atroposelective synthesis of axially chiral styrenes

(2017) Sheng-Cai Zheng et al.   Nature Communications

Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

(2016) Hong-Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isocoumarins, miraculous natural products blessed with diverse pharmacological activities

(2016) Aamer Saeed   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Kinetic Resolution of Axially Chiral 5- or 8-Substituted Quinolines via Asymmetric Transfer Hydrogenation

(2016) Jie Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Combining Organocatalysis with Central-to-Axial Chirality Conversion: Atroposelective Hantzsch-Type Synthesis of 4-Arylpyridines

(2015) Ophélie Quinonero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzedortho-Heteroarylation of Phenols through Internal Oxidative CH Activation: Rapid Screening of Single-Molecular White-Light-Emitting Materials

(2015) Bijin Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Artificial Molecular Machines

(2015) Sundus Erbas-Cakmak et al.   CHEMICAL REVIEWS

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Palladium catalyzed asymmetric Suzuki–Miyaura coupling reactions to axially chiral biaryl compounds: Chiral ligands and recent advances

(2015) Dao Zhang et al.   COORDINATION CHEMISTRY REVIEWS

A twist of nature – the significance of atropisomers in biological systems

(2015) Jamie E. Smyth et al.   NATURAL PRODUCT REPORTS

Kinetic Resolution of 1,1′-Biaryl-2,2′-Diols and Amino Alcohols through NHC-Catalyzed Atroposelective Acylation

(2014) Shenci Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Natural and Synthetic Chromenes, Fused Chromenes, and Versatility of Dihydrobenzo[h]chromenes in Organic Synthesis

(2014) Ramendra Pratap et al.   CHEMICAL REVIEWS

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Helicene Quinones: Redox-Triggered Chiroptical Switching and Chiral Recognition of the Semiquinone Radical Anion Lithium Salt by Electron Nuclear Double Resonance Spectroscopy

(2014) David Schweinfurth et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spontaneous transfer of chirality in an atropisomerically enriched two-axis system

(2014) Kimberly T. Barrett et al.   NATURE

P,N ligands in asymmetric catalysis

(2013) Michael P. Carroll et al.   CHEMICAL SOCIETY REVIEWS

Biological Stereoselectivity of Atropisomeric Natural Products and Drugs

(2013) Arie Zask et al.   CHIRALITY

Base-catalyzed Schmittel cycloisomerization of o-phenylenediyne-linked bis(arenol)s to indeno[1,2-c]chromenes

(2013) Masaki Furusawa et al.   TETRAHEDRON LETTERS

Vinylidene–Quinone Methides, Photochemical Generation and β-Silicon Effect on Reactivity

(2012) Filippo Doria et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of (R)-Mellein by a Partially Reducing Iterative Polyketide Synthase

(2012) Huihua Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Fluorescent Sensors: A Tale of BINOL

(2011) Lin Pu   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis and Stereochemical Behavior of a New Chiral Oxa[7]heterohelicene

(2011) Ryo Irie et al.   CHEMISTRY LETTERS

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

The recent synthesis and application of silicon-stereogenic silanes: A renewed and significant challenge in asymmetric synthesis

(2010) Li-Wen Xu et al.   CHEMICAL SOCIETY REVIEWS

Helical Chiral 2-Aminopyridinium Ions: A New Class of Hydrogen Bond Donor Catalysts

(2010) Norito Takenaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Biphenols from 1,4-Diketones by Traceless Central-to-Axial Chirality Exchange

(2010) Fenghai Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phenolic analogs of the N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A, from Ancistrocladus cochinchinensis (Ancistrocladaceae), with improved antiprotozoal activities

(2010) Gerhard Bringmann et al.   PHYTOCHEMISTRY

Dynamic Kinetic Resolution of Biaryl Atropisomers via Peptide-Catalyzed Asymmetric Bromination

(2010) J. L. Gustafson et al.   SCIENCE

Hollow Six-Stranded Helical Columns of a Helicene

(2009) Maxim A. Shcherbina et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS

Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions

(2009) Aleksandr V. Marenich et al.   JOURNAL OF PHYSICAL CHEMISTRY B