Plant-produced anti-dengue virus monoclonal antibodies exhibit reduced antibody-dependent enhancement of infection activity

SAGE committee advice on dengue vaccine

(2016) Tikki Pang   LANCET INFECTIOUS DISEASES

Plant specific N-glycans do not have proven adverse effects in humans

(2016) Yoseph Shaaltiel et al.   NATURE BIOTECHNOLOGY

Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus

(2016) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

Glycoengineering of plants yields glycoproteins with polysialylation and other defined N-glycoforms

(2016) Qiang Chen   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody-dependent enhancement of dengue virus infection inhibits RLR-mediated Type-I IFN-independent signalling through upregulation of cellular autophagy

(2016) Xinwei Huang et al.   Scientific Reports

Fc receptors in antibody-dependent enhancement of viral infections

(2015) Adam Taylor et al.   IMMUNOLOGICAL REVIEWS

Plant-made pharmaceuticals: from ‘Edible Vaccines’ to Ebola therapeutics

(2015) Charles Arntzen   PLANT BIOTECHNOLOGY JOURNAL

Gene Delivery into Plant Cells for Recombinant Protein Production

(2015) Qiang Chen et al.   Biomed Research International

Controlled glycosylation of plant-produced recombinant proteins

(2014) Richard Strasser et al.   CURRENT OPINION IN BIOTECHNOLOGY

Delivery of antiviral small interfering RNA with gold nanoparticles inhibits dengue virus infection in vitro

(2014) A. M. Paul et al.   JOURNAL OF GENERAL VIROLOGY

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

(2014) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants

(2014) Huafang Lai et al.   PLANT BIOTECHNOLOGY JOURNAL

Generation and Analysis of Novel Plant-Derived Antibody-Based Therapeutic Molecules against West Nile Virus

(2014) Junyun He et al.   PLoS One

Expression and glycoengineering of functionally active heteromultimeric IgM in plants

(2014) A. Loos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Manufacturing Economics of Plant-Made Biologics: Case Studies in Therapeutic and Industrial Enzymes

(2014) Daniel Tusé et al.   Biomed Research International

Plant glyco-biotechnology on the way to synthetic biology

(2014) Andreas Loos et al.   Frontiers in Plant Science

Human Fc RII Cytoplasmic Domains Differentially Influence Antibody-Mediated Dengue Virus Infection

(2013) K. Boonnak et al.   JOURNAL OF IMMUNOLOGY

Dengue Virus Neutralization in Cells Expressing Fc Gamma Receptors

(2013) Tanu Chawla et al.   PLoS One

Therapeutic Efficacy of Antibodies Lacking FcγR against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies

(2013) Katherine L. Williams et al.   PLoS Pathogens

Epidemiology of dengue: past, present and future prospects

(2013) Annelies Wilder-Smith et al.   Clinical Epidemiology

IgG-Fc glycoengineering in non-mammalian expression hosts

(2012) Andreas Loos et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The impact of glycosylation on monoclonal antibody conformation and stability

(2012) Kai Zheng et al.   mAbs

Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques

(2012) G. G. Olinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions

(2012) R. de Alwis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune Response to Dengue Virus and Prospects for a Vaccine

(2011) Brian R. Murphy et al.   Annual Review of Immunology

Geminiviral vectors based on bean yellow dwarf virus for production of vaccine antigens and monoclonal antibodies in plants

(2011) Qiang Chen et al.   Human vaccines & immunotherapeutics

A Novel System for Rapid and Cost-Effective Production of Detection and Diagnostic Reagents of West Nile Virus in Plants

(2011) Junyun He et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Robust production of virus-like particles and monoclonal antibodies with geminiviral replicon vectors in lettuce

(2011) Huafang Lai et al.   PLANT BIOTECHNOLOGY JOURNAL

Bioprocessing of plant-derived virus-like particles of Norwalk virus capsid protein under current Good Manufacture Practice regulations

(2011) Huafang Lai et al.   PLANT CELL REPORTS

A Broadly Flavivirus Cross-Neutralizing Monoclonal Antibody that Recognizes a Novel Epitope within the Fusion Loop of E Protein

(2011) Yong-Qiang Deng et al.   PLoS One

Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection

(2011) K. R. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

(2011) L. Zeitlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In-Depth Analysis of the Antibody Response of Individuals Exposed to Primary Dengue Virus Infection

(2011) Ruklanthi de Alwis et al.   PLoS Neglected Tropical Diseases

Rapid, high-yield production in plants of individualized idiotype vaccines for non-Hodgkin's lymphoma

(2010) M. Bendandi et al.   ANNALS OF ONCOLOGY

High-level rapid production of full-size monoclonal antibodies in plants by a single-vector DNA replicon system

(2010) Zhong Huang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Glycosylation influences on the aggregation propensity of therapeutic monoclonal antibodies

(2010) Veysel Kayser et al.   Biotechnology Journal

The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

(2010) Martina Beltramello et al.   Cell Host & Microbe

Cell Type Specificity and Host Genetic Polymorphisms Influence Antibody-Dependent Enhancement of Dengue Virus Infection

(2010) K. Boonnak et al.   JOURNAL OF VIROLOGY

Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes

(2010) Scott B Halstead et al.   LANCET INFECTIOUS DISEASES

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

(2010) Damian Houde et al.   MOLECULAR & CELLULAR PROTEOMICS

Production of antibodies in plants: status after twenty years

(2010) Benoit De Muynck et al.   PLANT BIOTECHNOLOGY JOURNAL

Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice

(2010) H. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification

(2010) Scott J. Balsitis et al.   PLoS Pathogens

Complement Protein C1q Reduces the Stoichiometric Threshold for Antibody-Mediated Neutralization of West Nile Virus

(2009) Erin Mehlhop et al.   Cell Host & Microbe

Dengue virus neutralization is modulated by IgG antibody subclass and Fcγ receptor subtype

(2009) W.W. Shanaka I. Rodrigo et al.   VIROLOGY

Global Spread and Persistence of Dengue

(2008) Jennifer L. Kyle et al.   Annual Review of Microbiology

Geographic Expansion of Dengue: The Impact of International Travel

(2008) Annelies Wilder-Smith et al.   MEDICAL CLINICS OF NORTH AMERICA

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

(2008) Richard Strasser et al.   PLANT BIOTECHNOLOGY JOURNAL

Analysis of immunoglobulin glycosylation by LC-ESI-MS of glycopeptides and oligosaccharides

(2008) Johannes Stadlmann et al.   PROTEOMICS

Vaccine-induced enhancement of viral infections

(2008) W. Huisman et al.   VACCINE

Glycosylation of Recombinant Antibody Therapeutics

(2005) Royston Jefferis   BIOTECHNOLOGY PROGRESS