Ubiquitin ligase E6AP mediates nonproteolytic polyubiquitylation of β-catenin independent of the E6 oncoprotein

Regulation of the Wnt/β-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 Oncoproteins

(2015) Jesus Bello et al.   Viruses-Basel

Aldolase positively regulates of the canonical Wnt signaling pathway

(2014) Michal Caspi et al.   Molecular Cancer

HPV16 E6 and E6AP differentially cooperate to stimulate or augment Wnt signaling

(2014) Sophia Sominsky et al.   VIROLOGY

Mammalian HECT ubiquitin-protein ligases: Biological and pathophysiological aspects

(2013) Martin Scheffner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Looking beyond the Wnt pathway for the deep nature of β-catenin

(2013) François Fagotto   EMBO REPORTS

HectD1 E3 Ligase Modifies Adenomatous Polyposis Coli (APC) with Polyubiquitin to Promote the APC-Axin Interaction

(2013) Hoanh Tran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

c-Cbl, a Ubiquitin E3 Ligase That Targets Active β-Catenin

(2013) Vipul Chitalia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smurf1-Mediated Lys29-Linked Nonproteolytic Polyubiquitination of Axin Negatively Regulates Wnt/ -Catenin Signaling

(2013) C. Fei et al.   MOLECULAR AND CELLULAR BIOLOGY

E6AP in the Brain: One Protein, Dual Function, Multiple Diseases

(2013) Jimmy El Hokayem et al.   MOLECULAR NEUROBIOLOGY

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin

(2012) Brigitte Gerard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Identification and Proteomic Analysis of Distinct UBE3A/E6AP Protein Complexes

(2012) G. Martinez-Noel et al.   MOLECULAR AND CELLULAR BIOLOGY

Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

(2012) Yogesh Kulathu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The E6AP E3 ubiquitin ligase regulates the cellular response to oxidative stress

(2012) K Wolyniec et al.   ONCOGENE

Regulation of the Human Papillomavirus Type 18 E6/E6AP Ubiquitin Ligase Complex by the HECT Domain-Containing Protein EDD

(2011) V. Tomaic et al.   JOURNAL OF VIROLOGY

E6AP is required for replicative and oncogene-induced senescence in mouse embryo fibroblasts

(2011) Y Levav-Cohen et al.   ONCOGENE

The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators

(2010) Jia-Ling Teo et al.   ADVANCED DRUG DELIVERY REVIEWS

Regulation of the Polycomb protein RING1B ubiquitination by USP7

(2010) Prim de Bie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

(2010) Paul L. Greer et al.   CELL

The various roles of ubiquitin in Wnt pathway regulation

(2010) Daniele V. F. Tauriello et al.   CELL CYCLE

E6AP ubiquitin ligase mediates ubiquitin-dependent degradation of peroxiredoxin 1

(2010) Junichi Nasu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The EDD E3 ubiquitin ligase ubiquitinates and up-regulates β-catenin

(2010) Avital Hay-Koren et al.   MOLECULAR BIOLOGY OF THE CELL

Loss of the Tumor Suppressor CYLD Enhances Wnt/β-Catenin Signaling through K63-Linked Ubiquitination of Dvl

(2010) Daniele V.F. Tauriello et al.   MOLECULAR CELL

Wnt signal transduction pathways

(2010) Yuko Komiya et al.   Organogenesis

E6AP promotes the degradation of the PML tumor suppressor

(2009) I Louria-Hayon et al.   CELL DEATH AND DIFFERENTIATION

Lysine 63 Polyubiquitination in Immunotherapy and in Cancer-promoting Inflammation

(2009) I. Martinez-Forero et al.   CLINICAL CANCER RESEARCH

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Identification of annexin A1 as a novel substrate for E6AP-mediated ubiquitylation

(2009) Tetsu Shimoji et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

β-Catenin hits chromatin: regulation of Wnt target gene activation

(2009) Christian Mosimann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The stability of the human papillomavirus E6 oncoprotein is E6AP dependent

(2009) Vjekoslav Tomaić et al.   VIROLOGY

HPV16 E6 augments Wnt signaling in an E6AP-dependent manner

(2009) Hava Lichtig et al.   VIROLOGY

Ubiquitin ligase E6-AP and its role in human disease

(2008) Konstantin Matentzoglu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

E3 ubiquitin ligase E6AP-mediated TSC2 turnover in the presence and absence of HPV16 E6

(2008) Li Zheng et al.   GENES TO CELLS

Jade-1 inhibits Wnt signalling by ubiquitylating β-catenin and mediates Wnt pathway inhibition by pVHL

(2008) Vipul C. Chitalia et al.   NATURE CELL BIOLOGY

Nuclear GSK-3β inhibits the canonical Wnt signalling pathway in a β-catenin phosphorylation-independent manner

(2008) M Caspi et al.   ONCOGENE

Papillomavirus E6 proteins

(2008) Heather L. Howie et al.   VIROLOGY