The E6AP E3 ubiquitin ligase regulates the cellular response to oxidative stress

Overexpression of ligase defective E6-associated protein, E6-AP, results in mammary tumorigenesis

(2011) Sivapriya Ramamoorthy et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumor suppressor genes and ROS: complex networks of interactions

(2011) Beyza Vurusaner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

(2011) U Weyemi et al.   ONCOGENE

E6AP is required for replicative and oncogene-induced senescence in mouse embryo fibroblasts

(2011) Y Levav-Cohen et al.   ONCOGENE

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine

(2010) Barbara van Loon et al.   DNA REPAIR

E6AP ubiquitin ligase mediates ubiquitin-dependent degradation of peroxiredoxin 1

(2010) Junichi Nasu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pro-Senescent Effect of Hydrogen Peroxide on Cancer Cells and Its Possible Application to Tumor Suppression

(2009) Kaichi YOSHIZAKI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity

(2009) Juxiang Cao et al.   EMBO JOURNAL

Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma

(2009) Mee-Kyung Cha et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress

(2009) K Wolyniec et al.   ONCOGENE

Ubiquitin ligase E6-AP and its role in human disease

(2008) Konstantin Matentzoglu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Cellular responses to reactive oxygen species-induced DNA damage and aging

(2008) Catharina Bertram et al.   BIOLOGICAL CHEMISTRY

HPV E6, E6AP and cervical cancer

(2008) Sylvie Beaudenon et al.   BMC BIOCHEMISTRY

Free radicals and senescence

(2008) Teng Lu et al.   EXPERIMENTAL CELL RESEARCH

Oncogene activation in melanocytes links reactive oxygen to multinucleated phenotype and senescence

(2008) C Leikam et al.   ONCOGENE