Syndromic and Nonsyndromic Obesity: Underlying Genetic Causes in Humans

The disGeNET cytoscape app: exploring and visualizing disease genomics data

(2021) Janet Piñero et al.   Computational and Structural Biotechnology Journal

Dual effect of the GHRL gene variant in the molecular pathogenesis of obesity

(2021) E Becer et al.   Balkan Journal of Medical Genetics

The Impact of Variants in Four Genes: MC4R, FTO, PPARG and PPARGC1A in Overweight and Obesity in a Large Sample of the Brazilian Population

(2021) Gabriel Vaisam Castro et al.   BIOCHEMICAL GENETICS

Implication of Heterozygous Variants in Genes of the Leptin–Melanocortin Pathway in Severe Obesity

(2021) Sophie Courbage et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Polymorphisms on rs9939609 FTO and rs17782313 MC4R genes in children and adolescent obesity: a systematic review

(2021) Cristina Maria Mendes Resende et al.   NUTRITION

Two Cases With an Early Presented Proopiomelanocortin Deficiency—A Long-Term Follow-Up and Systematic Literature Review

(2021) Nadan Gregoric et al.   Frontiers in Endocrinology

Evidence from a meta-analysis for association of MC4R rs17782313 and FTO rs9939609 polymorphisms with susceptibility to obesity in children

(2021) Seyed Alireza Dastgheib et al.   Diabetes & Metabolic Syndrome-Clinical Research & Reviews

AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity

(2021) Muhammad Sufyan Vohra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Associations between ghrelin and leptin and neural food cue reactivity in a fasted and sated state

(2021) Mirjam C.M. Wever et al.   NEUROIMAGE

A Targeted Next Generation Sequencing Panel for Non-syndromic Early Onset Severe Obesity and Identification of Novel Likely -Pathogenic Variants in the MC4R and LEP Genes

(2020) Vaman Khadilkar et al.   INDIAN JOURNAL OF PEDIATRICS

Association between MC4R rs17782313 genotype and obesity: A meta-analysis

(2020) Keping Yu et al.   GENE

A Novel Missense Variant in PHF6 Gene Causing Börjeson-Forssman-Lehman Syndrome

(2020) Anikha Bellad et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Single-Cell RNA-seq Reveals Obesity-Induced Alterations in the Brca1-Mutated Mammary Gland Microenvironment

(2020) Pang-Kuo Lo et al.   Cancers

Genetic Determinants of Childhood Obesity

(2020) Sheridan H. Littleton et al.   Molecular Diagnosis & Therapy

Growth Hormone Receptor Regulation in Cancer and Chronic Diseases

(2020) Ger J. Strous et al.   Frontiers in Endocrinology

Clinical and molecular spectrum of CHOPS syndrome

(2019) Sarah E. Raible et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Novel Mutations in Obesity-Related Genes in Turkish Children with Non-Syndromic Early Onset Severe Obesity: A Multicentre Study

(2019) Ayşehan Akıncı et al.   Journal of Clinical Research in Pediatric Endocrinology

Molecular genetic classification in Prader-Willi syndrome: a multisite cohort study

(2018) Merlin G Butler et al.   JOURNAL OF MEDICAL GENETICS

Genetic obesity: next-generation sequencing results of 1230 patients with obesity

(2018) Lotte Kleinendorst et al.   JOURNAL OF MEDICAL GENETICS

Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs

(2018) Shabana et al.   Lipids in Health and Disease

A novel mutation in the proopiomelanocortin (POMC) gene of a Hispanic child: metformin treatment shows a beneficial impact on the body mass index

(2018) Mark A. Hilado et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Temple syndrome: comprehensive molecular and clinical findings in 32 Japanese patients

(2017) Masayo Kagami et al.   GENETICS IN MEDICINE

Genetics of non-syndromic childhood obesity and the use of high-throughput DNA sequencing technologies

(2017) Ana Carolina Proença da Fonseca et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Next-generation sequencing of the monogenic obesity genes LEP , LEPR , MC4R , PCSK1 and POMC in a Norwegian cohort of patients with morbid obesity and normal weight controls

(2017) Gry B.N. Nordang et al.   MOLECULAR GENETICS AND METABOLISM

A systematic review of genetic syndromes with obesity

(2017) Y. Kaur et al.   Obesity Reviews

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

(2017) Audrey E. Hendricks et al.   Scientific Reports

Disruption of POGZ Is Associated with Intellectual Disability and Autism Spectrum Disorders

(2016) Holly A.F. Stessman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Adolescents and adults affected by Cornelia de Lange syndrome: A report of 73 Italian patients

(2016) Milena Mariani et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

DisGeNET-RDF: harnessing the innovative power of the Semantic Web to explore the genetic basis of diseases

(2016) Núria Queralt-Rosinach et al.   BIOINFORMATICS

Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity

(2016) M. Pigeyre et al.   CLINICAL SCIENCE

The Hunger Genes: Pathways to Obesity

(2015) Agatha A. van der Klaauw et al.   CELL

Familial transmission of 5p13.2 duplication due to maternal der(X)ins(X;5)

(2015) Lauren C. Walters-Sen et al.   European Journal of Medical Genetics

Clinically relevant known and candidate genes for obesity and their overlap with human infertility and reproduction

(2015) Merlin G. Butler et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes

(2015) J. Pinero et al.   Database-The Journal of Biological Databases and Curation

Obesity genetics in mouse and human: back and forth, and back again

(2015) Fereshteh T. Yazdi et al.   PeerJ

Mini-Review Prader-Willi-like phenotypes: a systematic review of their chromosomal abnormalities

(2014) C.F. Rocha et al.   GENETICS AND MOLECULAR RESEARCH

Whole Exome Sequencing of Extreme Morbid Obesity Patients: Translational Implications for Obesity and Related Disorders

(2014) Gilberto Paz-Filho et al.   Genes

Growth patterns of patients with 1p36 deletion syndrome

(2013) Noriko Sangu et al.   CONGENITAL ANOMALIES

Structural Chromosome Abnormalities Associated with Obesity: Report of Four New Subjects and Review of Literature

(2012) Majed J. Dasouki et al.   CURRENT GENOMICS

Fragile X Syndrome

(2012) Yingratana McLennan et al.   CURRENT GENOMICS

Genetics of Obesity: What have we Learned?

(2012) Helene Choquet et al.   CURRENT GENOMICS

Molecular Basis of Obesity: Current Status and Future Prospects

(2012) Helene Choquet et al.   CURRENT GENOMICS

Prader-Willi Syndrome: Obesity due to Genomic Imprinting

(2012) Merlin G. Butler   CURRENT GENOMICS

Alstrom Syndrome: Genetics and Clinical Overview

(2012) Jan D. Marshall et al.   CURRENT GENOMICS

The modifier effect of the BDNF gene in the phenotype of the WAGRO syndrome

(2012) Raquel Rodríguez-López et al.   GENE

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups

(2010) André Scherag et al.   PLoS Genetics

Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference

(2009) Florianne Bauer et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Genetic and environmental effects on body mass index during adolescence: a prospective study among Finnish twins

(2009) H-R Lajunen et al.   INTERNATIONAL JOURNAL OF OBESITY

Carpenter Syndrome

(2009) Pip Hidestrand et al.   JOURNAL OF CRANIOFACIAL SURGERY

Kallmann syndrome

(2008) Catherine Dodé et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Detailed phenotype–genotype study in five patients with chromosome 6q16 deletion: narrowing the critical region for Prader–Willi-like phenotype

(2008) Maria Clara Bonaglia et al.   EUROPEAN JOURNAL OF HUMAN GENETICS