Poxvirus Targeting of E3 Ligase β-TrCP by Molecular Mimicry: A Mechanism to Inhibit NF-κB Activation and Promote Immune Evasion and Virulence

β -TrCP Dependency of HIV-1 Vpu-Induced Downregulation of CD4 and BST-2/Tetherin

(2012) Fabien P. Blanchet et al.   CURRENT HIV RESEARCH

Regulation of NF-κB by ubiquitination and degradation of the IκBs

(2012) Naama Kanarek et al.   IMMUNOLOGICAL REVIEWS

Vaccinia virus protein C4 inhibits NF- B activation and promotes virus virulence

(2012) S. W. J. Ember et al.   JOURNAL OF GENERAL VIROLOGY

Mapping the IκB Kinase β (IKKβ)-binding Interface of the B14 Protein, a Vaccinia Virus Inhibitor of IKKβ-mediated Activation of Nuclear Factor κB

(2011) Camilla T. O. Benfield et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How vaccinia virus has evolved to subvert the host immune response

(2011) Mohammad W. Bahar et al.   JOURNAL OF STRUCTURAL BIOLOGY

Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7

(2011) Leonie Unterholzner et al.   PLoS Pathogens

Inhibition of Apoptosis and NF-κB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence

(2011) Carlos Maluquer de Motes et al.   PLoS Pathogens

Mutations in modified virus Ankara protein 183 render it a non-functional counterpart of B14, an inhibitor of nuclear factor  B activation

(2010) L. E. McCoy et al.   JOURNAL OF GENERAL VIROLOGY

Inhibition of the RNA polymerase III-mediated dsDNA-sensing pathway of innate immunity by vaccinia virus protein E3

(2010) R. Valentine et al.   JOURNAL OF GENERAL VIROLOGY

A Vaccinia Virus Deletion Mutant Reveals the Presence of Additional Inhibitors of NF- B

(2010) K. Fagan-Garcia et al.   JOURNAL OF VIROLOGY

Repulsion of Superinfecting Virions: A Mechanism for Rapid Virus Spread

(2010) V. Doceul et al.   SCIENCE

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Approaching the Asymptote: 20 Years Later

(2009) Ruslan Medzhitov   IMMUNITY

Vaccinia Virus E3 Suppresses Expression of Diverse Cytokines through Inhibition of the PKR, NF- B, and IRF3 Pathways

(2009) C. Myskiw et al.   JOURNAL OF VIROLOGY

Targeting of immune signalling networks by bacterial pathogens

(2009) Igor E. Brodsky et al.   NATURE CELL BIOLOGY

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism

(2009) Joel W. Graff et al.   PLoS Pathogens

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL

Vaccinia virus protein C16 acts intracellularly to modulate the host response and promote virulence

(2008) A. S. Fahy et al.   JOURNAL OF GENERAL VIROLOGY

Inhibition of IκB Kinase by Vaccinia Virus Virulence Factor B14

(2008) Ron A.-J. Chen et al.   PLoS Pathogens

Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes

(2008) E. Assarsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis

(2008) Stephen C. Graham et al.   PLoS Pathogens