Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling

Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain

(2015) Peishen Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanism of phosphorylation-dependent arrestin activation

(2014) Martin K Ostermaier et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors

(2014) N. Bojjireddy et al.   JOURNAL OF CELL SCIENCE

Visualization of arrestin recruitment by a G-protein-coupled receptor

(2014) Arun K. Shukla et al.   NATURE

Cyclic AMP synthesis and hydrolysis in the normal and failing heart

(2014) Aziz Guellich et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Sister kinetochores are mechanically fused during meiosis I in yeast

(2014) K. K. Sarangapani et al.   SCIENCE

Proteinase-activated receptors (PARs) – focus on receptor-receptor-interactions and their physiological and pathophysiological impact

(2013) Frank Gieseler et al.   Cell Communication and Signaling

β-Arrestin Promotes Wnt-induced Low Density Lipoprotein Receptor-related Protein 6 (Lrp6) Phosphorylation via Increased Membrane Recruitment of Amer1 Protein

(2013) Vítězslav Kříž et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative properties and receptor reserve of the DAG and PKC branch of Gq-coupled receptor signaling

(2013) Björn H. Falkenburger et al.   JOURNAL OF GENERAL PHYSIOLOGY

Quantitative properties and receptor reserve of the IP3and calcium branch of Gq-coupled receptor signaling

(2013) Eamonn J. Dickson et al.   JOURNAL OF GENERAL PHYSIOLOGY

Toward Drugs for Protease-Activated Receptor 2 (PAR2)

(2013) Mei-Kwan Yau et al.   JOURNAL OF MEDICINAL CHEMISTRY

Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling

(2012) Domitille Heitzler et al.   Molecular Systems Biology

High-resolution crystal structure of human protease-activated receptor 1

(2012) Cheng Zhang et al.   NATURE

Targeting proteinase-activated receptors: therapeutic potential and challenges

(2012) Rithwik Ramachandran et al.   NATURE REVIEWS DRUG DISCOVERY

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conformational dynamics of helix 8 in the GPCR rhodopsin controls arrestin activation in the desensitization process

(2011) K. Kirchberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-arrestin-mediated receptor trafficking and signal transduction

(2011) Sudha K. Shenoy et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Signal transduction by protease-activated receptors

(2010) Unice JK Soh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Kinetics of M1muscarinic receptor and G protein signaling to phospholipase C in living cells

(2010) Björn H. Falkenburger et al.   JOURNAL OF GENERAL PHYSIOLOGY

Cyclic AMP potentiates Ca2+-dependent exocytosis in pancreatic duct epithelial cells

(2010) Seung-Ryoung Jung et al.   JOURNAL OF GENERAL PHYSIOLOGY

Kinetics of PIP2metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells

(2010) Björn H. Falkenburger et al.   JOURNAL OF GENERAL PHYSIOLOGY

Quantitative Modeling of GRK-Mediated β2AR Regulation

(2010) Sharat J. Vayttaden et al.   PLoS Computational Biology

Use of Fluorescence Resonance Energy Transfer-based Biosensors for the Quantitative Analysis of Inositol 1,4,5-Trisphosphate Dynamics in Calcium Oscillations

(2009) Akihiko Tanimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Protease-activated Receptor-2 Differentially Regulates Desensitization and Internalization

(2009) Tiffany K. Ricks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fluorescence changes reveal kinetic steps of muscarinic receptor–mediated modulation of phosphoinositides and Kv7.2/7.3 K+channels

(2009) Jill B. Jensen et al.   JOURNAL OF GENERAL PHYSIOLOGY

Arrestin Competition Influences the Kinetics and Variability of the Single-Photon Responses of Mammalian Rod Photoreceptors

(2009) T. Doan et al.   JOURNAL OF NEUROSCIENCE

Control of Granule Mobility and Exocytosis by Ca2+-Dependent Formation of F-Actin in Pancreatic Duct Epithelial Cells

(2009) Seung-Ryoung Jung et al.   TRAFFIC

β-Arrestin Scaffolding of Phosphatidylinositol 4-Phosphate 5-Kinase Iα Promotes Agonist-stimulated Sequestration of the β2-Adrenergic Receptor

(2008) Christopher D. Nelson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protease-activated Receptor-2 Increases Exocytosis via Multiple Signal Transduction Pathways in Pancreatic Duct Epithelial Cells

(2008) Mean-Hwan Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY