Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma

Immune Modulation of the T Cell Response in Asthma through Wnt10b

(2016) Jordis Trischler et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Genotype-phenotype correlation ofCTNNB1mutations reveals different ß-catenin activity associated with liver tumor progression

(2016) Sandra Rebouissou et al.   HEPATOLOGY

Targeted and exome sequencing identified somatic mutations in hepatocellular carcinoma

(2016) Yosuke Hirotsu et al.   HEPATOLOGY RESEARCH

β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis

(2015) Satdarshan Pal Monga   GASTROENTEROLOGY

Modulation of HCV reinfection after orthotopic liver transplantation by fibroblast growth factor-2 and other non-interferon mediators

(2015) Nguyen Dinh Van et al.   GUT

Hepatitis C virus NS5A protein blocks epidermal growth factor receptor degradation via a proline motif- dependent interaction

(2015) Zsofia Igloi et al.   JOURNAL OF GENERAL VIROLOGY

PTPN11/Shp2 overexpression enhances liver cancer progression and predicts poor prognosis of patients

(2015) Tao Han et al.   JOURNAL OF HEPATOLOGY

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

(2015) Kornelius Schulze et al.   NATURE GENETICS

Hepatocellular Carcinoma with β-Catenin Mutation: Imaging and Pathologic Characteristics

(2015) Azusa Kitao et al.   RADIOLOGY

Inhibition of microRNA-199a-5p reduces the replication of HCV via regulating the pro-survival pathway

(2015) Hongwei Wang et al.   VIRUS RESEARCH

Interferon-α inducible protein 6 impairs EGFR activation by CD81 and inhibits hepatitis C virus infection

(2015) Keith Meyer et al.   Scientific Reports

Viral-Human Chimeric Transcript Predisposes Risk to Liver Cancer Development and Progression

(2014) Chi-Chiu Lau et al.   CANCER CELL

The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength

(2014) W. de Lau et al.   GENES & DEVELOPMENT

The Wnt/β-Catenin Pathway Attenuates Experimental Allergic Airway Disease

(2014) Sebastian Reuter et al.   JOURNAL OF IMMUNOLOGY

Transcriptomic Characterization of Hepatocellular Carcinoma with CTNNB1 Mutation

(2014) Xiao Ding et al.   PLoS One

Viruses exploit the function of epidermal growth factor receptor

(2014) Kai Zheng et al.   REVIEWS IN MEDICAL VIROLOGY

Promoter hypermethylation of Wnt pathway inhibitors in hepatitis C virus - induced multistep hepatocarcinogenesis

(2014) Muhammad Umer et al.   Virology Journal

Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

(2013) Z. Kan et al.   GENOME RESEARCH

Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections

(2013) Maria Lina Tornesello et al.   GENOMICS

Identification of driver genes in hepatocellular carcinoma by exome sequencing

(2013) Sean P. Cleary et al.   HEPATOLOGY

Hepatitis C virus core protein epigenetically silences SFRP1 and enhances HCC aggressiveness by inducing epithelial–mesenchymal transition

(2013) H Quan et al.   ONCOGENE

WNT Signaling Pathway Gene Polymorphisms and Risk of Hepatic Fibrosis and Inflammation in HCV-Infected Patients

(2013) Yanhong Liu et al.   PLoS One

Wnt-Pathway Activation in Two Molecular Classes of Hepatocellular Carcinoma and Experimental Modulation by Sorafenib

(2012) A. Lachenmayer et al.   CLINICAL CANCER RESEARCH

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

(2012) Hashem B. El-Serag   GASTROENTEROLOGY

Hepatitis C virus-induced up-regulation of microRNA-155 promotes hepatocarcinogenesis by activating Wnt signaling

(2012) Yiliang Zhang et al.   HEPATOLOGY

Oncogenic β-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice

(2012) Marie Anson et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatitis C Virus Induces Epidermal Growth Factor Receptor Activation via CD81 Binding for Viral Internalization and Entry

(2012) J. Diao et al.   JOURNAL OF VIROLOGY

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

(2012) Huai-Xiang Hao et al.   NATURE

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

(2012) Cécile Guichard et al.   NATURE GENETICS

β-Catenin signaling dosage dictates tissue-specific tumor predisposition in Apc-driven cancer

(2012) E R M Bakker et al.   ONCOGENE

Telaprevir/boceprevir era: From bench to bed and back

(2012) Qiuwei Pan   WORLD JOURNAL OF GASTROENTEROLOGY

Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening

(2011) Eric T. Sawey et al.   CANCER CELL

E-Cadherin and the Cytoskeletal Network in Colorectal Cancer Development and Metastasis

(2011) Andrea Buda et al.   CELL COMMUNICATION AND ADHESION

 -catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis

(2011) W. van Veelen et al.   GUT

Specific Armadillo Repeat Sequences Facilitate β-Catenin Nuclear Transport in Live Cells via Direct Binding to Nucleoporins Nup62, Nup153, and RanBP2/Nup358

(2011) Manisha Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SHP2 Tyrosine Phosphatase Converts Parafibromin/Cdc73 from a Tumor Suppressor to an Oncogenic Driver

(2011) Atsushi Takahashi et al.   MOLECULAR CELL

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

(2011) Meng Li et al.   NATURE GENETICS

Enhancement of Canonical Wnt/β-Catenin Signaling Activity by HCV Core Protein Promotes Cell Growth of Hepatocellular Carcinoma Cells

(2011) Jiao Liu et al.   PLoS One

Hypermethylated levels of E-cadherin promoter in Huh-7 cells expressing the HCV core protein

(2011) Maria Ripoli et al.   VIRUS RESEARCH

The Wnt/β-catenin pathway as a therapeutic target in human hepatocellular carcinoma

(2011) Rajae Dahmani et al.   Clinics and Research in Hepatology and Gastroenterology

MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene

(2010) S. Jiang et al.   CANCER RESEARCH

Frizzled1 is a marker of inflammatory macrophages, and its ligand Wnt3a is involved in reprogramming Mycobacterium tuberculosis-infected macrophages

(2010) Jan Neumann et al.   FASEB JOURNAL

Regulation of VSMC behavior by the cadherin-catenin complex

(2010) Cressida Lyon   Frontiers in Bioscience-Landmark

Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis

(2010) Christine Gauglhofer et al.   HEPATOLOGY

Convergence between Wnt-β-catenin and EGFR signaling in cancer

(2010) Tianhui Hu et al.   Molecular Cancer

HCV-related hepatocellular carcinoma: From chronic inflammation to cancer

(2009) Giuseppe Castello et al.   CLINICAL IMMUNOLOGY

The Epidermal Growth Factor Receptor: A Link Between Inflammation and Liver Cancer

(2009) Carmen Berasain et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hepatitis C virus NS5A protein interacts with  -catenin and stimulates its transcriptional activity in a phosphoinositide-3 kinase-dependent fashion

(2009) A. Milward et al.   JOURNAL OF GENERAL VIROLOGY

Nonstructural 5A protein activates β-catenin signaling cascades: Implication of hepatitis C virus-induced liver pathogenesis

(2009) Chul-Yong Park et al.   JOURNAL OF HEPATOLOGY

Should we be surprised at the paucity of response to EGFR inhibitors?

(2009) Barry A Gusterson et al.   LANCET ONCOLOGY

Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells

(2009) Haluk Yuzugullu et al.   Molecular Cancer

EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin

(2009) Haitao Ji et al.   MOLECULAR CELL

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma

(2008) A Bengochea et al.   BRITISH JOURNAL OF CANCER

Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating  -Catenin Signaling

(2008) R. Pai et al.   CANCER RESEARCH

Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene

(2008) Benjamin Cieply et al.   HEPATOLOGY

Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma

(2008) Madeleine Austinat et al.   Molecular Cancer

Alternative Wnt Signaling Is Initiated by Distinct Receptors

(2008) R. van Amerongen et al.   Science Signaling

Serial changes in expression of functionally clustered genes in progression of liver fibrosis in hepatitis C patients

(2008) Yoshiyuki Takahara et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Attenuation of N-nitrosodiethylamine-induced hepatocellular carcinogenesis by a novel flavonol—Morin

(2007) Venkatabalasubramanian Sivaramakrishnan et al.   CHEMICO-BIOLOGICAL INTERACTIONS