Single-Dose Induction of Osteogenic Differentiation of Mesenchymal Stem Cells Using a Cyclic AMP Activator, Forskolin

Regenerative Engineering Approaches to Scar-Free Skin Regeneration

(2021) Takayoshi Otsuka et al.   Regenerative Engineering and Translational Medicine

Effect of cAMP Signaling Regulation in Osteogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells

(2020) Sławomir Rumiński et al.   Cells

Mesenchymal Stem Cells Current Clinical Applications: A Systematic Review

(2020) David E. Rodríguez-Fuentes et al.   ARCHIVES OF MEDICAL RESEARCH

Subcellular Organization of the cAMP Signaling Pathway

(2020) Manuela Zaccolo et al.   PHARMACOLOGICAL REVIEWS

Mesenchymal stem cells: amazing remedies for bone and cartilage defects

(2020) Parisa Kangari et al.   Stem Cell Research & Therapy

Repositioning Tacrolimus: Evaluation of the Effect of Short-Term Tacrolimus Treatment on Osteoprogenitor Cells and Primary Cells for Bone Regenerative Engineering

(2019) Edward O'Neill et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

The roles of ions on bone regeneration

(2018) Edward O’Neill et al.   DRUG DISCOVERY TODAY

In vitro osteoblastic differentiation of mesenchymal stem cells generates cell layers with distinct properties

(2018) Hanna Hanna et al.   Stem Cell Research & Therapy

Drug repurposing: progress, challenges and recommendations

(2018) Sudeep Pushpakom et al.   NATURE REVIEWS DRUG DISCOVERY

Combining electrospinning and cell sheet technology for the development of a multiscale tissue engineered ligament construct (TELC)

(2017) Cedryck Vaquette et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Opportunities and challenges in phenotypic drug discovery: an industry perspective

(2017) John G. Moffat et al.   NATURE REVIEWS DRUG DISCOVERY

Osthole Enhances Osteogenesis in Osteoblasts by Elevating Transcription Factor Osterix via cAMP/CREB Signaling In Vitro and In Vivo

(2017) Zhong-Rong Zhang et al.   Nutrients

The Natural cAMP Elevating Compound Forskolin in Cancer Therapy: Is It Time?

(2016) Luigi Sapio et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review)

(2016) KUO YAN et al.   Molecular Medicine Reports

Drug Delivery Approaches in Addressing Clinical Pharmacology-Related Issues: Opportunities and Challenges

(2015) Hong Wen et al.   AAPS Journal

The scope and sequence of growth factor delivery for vascularized bone tissue regeneration

(2015) E.A. Bayer et al.   JOURNAL OF CONTROLLED RELEASE

Delivery of small molecules for bone regenerative engineering: preclinical studies and potential clinical applications

(2014) Cato T. Laurencin et al.   DRUG DISCOVERY TODAY

Small-molecule based musculoskeletal regenerative engineering

(2014) Kevin W.-H. Lo et al.   TRENDS IN BIOTECHNOLOGY

Osteoinductive Small Molecules: Growth Factor Alternatives for Bone Tissue Engineering

(2013) Aja Aravamudhan et al.   CURRENT PHARMACEUTICAL DESIGN

Phenotypic screens as a renewed approach for drug discovery

(2013) Wei Zheng et al.   DRUG DISCOVERY TODAY

One-day treatment of small molecule 8-bromo-cyclic AMP analogue induces cell-based VEGF production forin vitroangiogenesis and osteoblastic differentiation

(2013) Kevin W.-H. Lo et al.   Journal of Tissue Engineering and Regenerative Medicine

Mesenchymal Stem Cells in Bone Regeneration

(2013) M. Noelle Knight et al.   Advances in Wound Care

Studies of bone morphogenetic protein-based surgical repair

(2012) Kevin W.-H. Lo et al.   ADVANCED DRUG DELIVERY REVIEWS

The small molecule PKA-specific cyclic AMP analogue as an inducer of osteoblast-like cells differentiation and mineralization

(2012) Kevin W.-H. Lo et al.   Journal of Tissue Engineering and Regenerative Medicine

Lower-dose prescribing: Minimizing “side effects” of pharmaceuticals on society and the environment

(2012) Christian G. Daughton et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Regenerative Engineering

(2012) C. T. Laurencin et al.   Science Translational Medicine

The Cyclic AMP Pathway

(2012) P. Sassone-Corsi   Cold Spring Harbor Perspectives in Biology

Anabolic Effects of Intermittent PTH on Osteoblasts

(2012) Edward M. Greenfield   Current Molecular Pharmacology

Forskolin Enhances In Vivo Bone Formation by Human Mesenchymal Stromal Cells

(2011) Joyce Doorn et al.   TISSUE ENGINEERING PART A

Is bigger better? An argument for very low starting doses

(2010) J. P. McCormack et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Activation of cyclic amp/protein kinase: A signaling pathway enhances osteoblast cell adhesion on biomaterials for regenerative engineering

(2010) Kevin W.-H. Lo et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Plectranthus barbatus: A Review of Phytochemistry, Ethnobotanical Uses and Pharmacology – Part 2

(2010) Rawiya Alasbahi et al.   PLANTA MEDICA

Practical considerations for optimal designs in clinical dose finding studies

(2010) Frank Bretz et al.   STATISTICS IN MEDICINE

Cyclic nucleotide analogs as probes of signaling pathways

(2008) Heiko Poppe et al.   NATURE METHODS