Developmental regulation of myeloerythroid progenitor function by theLin28b–let-7–Hmga2axis

In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors

(2015) J. Xiang et al.   BLOOD

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

(2015) Franziska Paul et al.   CELL

Lin28 promotes the proliferative capacity of neural progenitor cells in brain development

(2015) M. Yang et al.   DEVELOPMENT

Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a

(2015) Yan Zhou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy

(2015) L D Wang et al.   LEUKEMIA

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

(2015) F. Notta et al.   SCIENCE

Precise let-7 expression levels balance organ regeneration against tumor suppression

(2015) Linwei Wu et al.   eLife

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice

(2014) K. Lam et al.   BLOOD

Lin28b Is Sufficient to Drive Liver Cancer and Necessary for Its Maintenance in Murine Models

(2014) Liem H. Nguyen et al.   CANCER CELL

miR-99a/100 125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGF  and Wnt signaling

(2014) S. Emmrich et al.   GENES & DEVELOPMENT

Lin28 sustains early renal progenitors and induces Wilms tumor

(2014) A. Urbach et al.   GENES & DEVELOPMENT

Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis

(2014) Weisheng Wu et al.   GENOME RESEARCH

Identification of nuclear-enriched miRNAs during mouse granulopoiesis

(2014) Justin JL Wong et al.   Journal of Hematology & Oncology

LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo

(2013) Y. T. Lee et al.   BLOOD

Lin28 Enhances Tissue Repair by Reprogramming Cellular Metabolism

(2013) Ng Shyh-Chang et al.   CELL

Orchestrated Intron Retention Regulates Normal Granulocyte Differentiation

(2013) Justin J.-L. Wong et al.   CELL

SLAM Family Markers Resolve Functionally Distinct Subpopulations of Hematopoietic Stem Cells and Multipotent Progenitors

(2013) Hideyuki Oguro et al.   Cell Stem Cell

Lin28: Primal Regulator of Growth and Metabolism in Stem Cells

(2013) Ng Shyh-Chang et al.   Cell Stem Cell

Polycomb Repressive Complex 2 Regulates Normal Hematopoietic Stem Cell Function in a Developmental-Stage-Specific Manner

(2013) Huafeng Xie et al.   Cell Stem Cell

miR-9 is a tumor suppressor in pediatric AML with t(8;21)

(2013) S Emmrich et al.   LEUKEMIA

The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells

(2013) Michael R. Copley et al.   NATURE CELL BIOLOGY

Fetal Deficiency of Lin28 Programs Life-Long Aberrations in Growth and Glucose Metabolism

(2013) Gen Shinoda et al.   STEM CELLS

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B

(2012) S. Rao et al.   BLOOD

Demand-adapted regulation of early hematopoiesis in infection and inflammation

(2012) H. Takizawa et al.   BLOOD

Blockade of miR-150 Maturation by MLL-Fusion/MYC/LIN-28 Is Required for MLL-Associated Leukemia

(2012) Xi Jiang et al.   CANCER CELL

The Transcriptional Landscape of Hematopoietic Stem Cell Ontogeny

(2012) Shannon McKinney-Freeman et al.   Cell Stem Cell

miRNA let-7c promotes granulocytic differentiation in acute myeloid leukemia

(2012) A Pelosi et al.   ONCOGENE

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

(2012) Joan Yuan et al.   SCIENCE

3'UTR-truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growth advantage at the level of HSC in mice

(2011) K. Ikeda et al.   BLOOD

Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells

(2011) M. Mochizuki-Kashio et al.   BLOOD

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

Stress erythropoiesis: new signals and new stress progenitor cells

(2011) Robert F Paulson et al.   CURRENT OPINION IN HEMATOLOGY

Sox17 expression confers self-renewal potential and fetal stem cell characteristics upon adult hematopoietic progenitors

(2011) S. He et al.   GENES & DEVELOPMENT

Advances in the understanding of haemoglobin switching

(2010) Vijay G. Sankaran et al.   BRITISH JOURNAL OF HAEMATOLOGY

Lin28: A MicroRNA Regulator with a Macro Role

(2010) Srinivas R. Viswanathan et al.   CELL

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

(2010) Marina Cavazzana-Calvo et al.   NATURE

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

PLZF is a regulator of homeostatic and cytokine-induced myeloid development

(2009) S. Doulatov et al.   GENES & DEVELOPMENT

Let-7 microRNAs are developmentally regulated in circulating human erythroid cells

(2009) Seung-Jae Noh et al.   Journal of Translational Medicine

A role for Lin28 in primordial germ-cell development and germ-cell malignancy

(2009) Jason A. West et al.   NATURE

Direct cell reprogramming is a stochastic process amenable to acceleration

(2009) Jacob Hanna et al.   NATURE

Lin28 promotes transformation and is associated with advanced human malignancies

(2009) Srinivas R Viswanathan et al.   NATURE GENETICS

Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression

(2008) Jinsuke Nishino et al.   CELL

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

Suppression of non-small cell lung tumor development by the let-7 microRNA family

(2008) M. S. Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE