Combined immunodeficiency and Epstein-Barr virus–induced B cell malignancy in humans with inherited CD70 deficiency

Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery

(2016) Eric M Scott et al.   NATURE GENETICS

The mutation significance cutoff: gene-level thresholds for variant predictions

(2016) Yuval Itan et al.   NATURE METHODS

The CD27–CD70 pathway and pathogenesis of autoimmune disease

(2016) Bobby Kwanghoon Han et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition

(2016) Hyung-Joon Kwon et al.   Nature Communications

Primary immunodeficiencies and the control of Epstein-Barr virus infection

(2015) Umaimainthan Palendira et al.   Annals of the New York Academy of Sciences

The Immunology of Epstein-Barr Virus–Induced Disease

(2015) Graham S. Taylor et al.   Annual Review of Immunology

Novel mutations in TNFRSF7/CD27: Clinical, immunologic, and genetic characterization of human CD27 deficiency

(2015) Omar K. Alkhairy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

RAC2 loss-of-function mutation in 2 siblings with characteristics of common variable immunodeficiency

(2015) Omar K. Alkhairy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

X-linked Inhibitor of Apoptosis Protein Deficiency: More than an X-linked Lymphoproliferative Syndrome

(2015) Claire Aguilar et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015

(2015) Capucine Picard et al.   JOURNAL OF CLINICAL IMMUNOLOGY

CD70: An emerging target in cancer immunotherapy

(2015) J. Jacobs et al.   PHARMACOLOGY & THERAPEUTICS

Human genetic basis of interindividual variability in the course of infection

(2015) Jean-Laurent Casanova   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human gene damage index as a gene-level approach to prioritizing exome variants

(2015) Yuval Itan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Severe infectious diseases of childhood as monogenic inborn errors of immunity

(2015) Jean-Laurent Casanova   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients

(2014) N. F. C. C. de Miranda et al.   BLOOD

Hemophagocytic lymphohistiocytosis and primary immune deficiency disorders

(2014) Yoram Faitelson et al.   CLINICAL IMMUNOLOGY

A hypomorphic recombination-activating gene 1 ( RAG1 ) mutation resulting in a phenotype resembling common variable immunodeficiency

(2014) Hassan Abolhassani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

XLP: Clinical Features and Molecular Etiology due to Mutations in SH2D1A Encoding SAP

(2014) Stuart G Tangye   JOURNAL OF CLINICAL IMMUNOLOGY

CD27 Defines Phenotypically and Functionally Different Human NK Cell Subsets

(2014) M. T. M. Vossen et al.   JOURNAL OF IMMUNOLOGY

Dual Function of CD70 in Viral Infection: Modulator of Early Cytokine Responses and Activator of Adaptive Responses

(2014) Atef Allam et al.   JOURNAL OF IMMUNOLOGY

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Mg2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D

(2013) B. Chaigne-Delalande et al.   SCIENCE

Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27

(2012) E. Salzer et al.   HAEMATOLOGICA

CD70 Deficiency Impairs Effector CD8 T Cell Generation and Viral Clearance but Is Dispensable for the Recall Response to Lymphocytic Choriomeningitis Virus

(2012) I. Munitic et al.   JOURNAL OF IMMUNOLOGY

Evolving role of 2B4/CD244 in T and NK cell responses during virus infection

(2012) Stephen N. Waggoner et al.   Frontiers in Immunology

SPICE: Exploration and analysis of post-cytometric complex multivariate datasets

(2011) Mario Roederer et al.   CYTOMETRY PART A

CD27-deficient mice show normal NK-cell differentiation but impaired function upon stimulation

(2011) Veerle De Colvenaer et al.   IMMUNOLOGY AND CELL BIOLOGY

Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas

(2011) René Scholtysik et al.   INTERNATIONAL JOURNAL OF CANCER

CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia

(2011) Joris M. van Montfrans et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP

(2011) Umaimainthan Palendira et al.   PLOS BIOLOGY

Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets

(2010) A. D. Hislop et al.   BLOOD

Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors

(2009) Y. T. Bryceson et al.   BLOOD

Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology

(2009) Martijn A. Nolte et al.   IMMUNOLOGICAL REVIEWS

Application of CD27 as a marker for distinguishing human NK cell subsets

(2008) A. Silva et al.   INTERNATIONAL IMMUNOLOGY