Live cell imaging to understand monocyte, macrophage, and dendritic cell function in atherosclerosis

MISTICA: Minimum Spanning Tree-Based Coarse Image Alignment for Microscopy Image Sequences

(2016) Nilanjan Ray et al.   IEEE Journal of Biomedical and Health Informatics

Intravital live cell triggered imaging system reveals monocyte patrolling and macrophage migration in atherosclerotic arteries

(2015) Sara McArdle et al.   JOURNAL OF BIOMEDICAL OPTICS

CX3CR1 Reduces Kidney Fibrosis by Inhibiting Local Proliferation of Profibrotic Macrophages

(2015) Daniel R. Engel et al.   JOURNAL OF IMMUNOLOGY

Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation

(2015) Iftach Shaked et al.   NATURE IMMUNOLOGY

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

(2015) Etsuo A Susaki et al.   Nature Protocols

Patrolling monocytes control tumor metastasis to the lung

(2015) R. N. Hanna et al.   SCIENCE

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

(2015) Elzbieta Kolaczkowska et al.   Nature Communications

Photo-activatable Cre recombinase regulates gene expression in vivo

(2015) Suzanne E. Schindler et al.   Scientific Reports

Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

(2014) Miranda L. Broz et al.   CANCER CELL

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

(2014) David Gosselin et al.   CELL

High-resolution intravital imaging reveals that blood-derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury

(2014) Teresa A. Evans et al.   EXPERIMENTAL NEUROLOGY

Frontcover

(2014)   IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS

GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment

(2014) Xiaoming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

(2014) Charlotte Giesen et al.   NATURE METHODS

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

(2014) Raju Tomer et al.   Nature Protocols

The MacBlue Binary Transgene (csf1r-gal4VP16/UAS-ECFP) Provides a Novel Marker for Visualisation of Subsets of Monocytes, Macrophages and Dendritic Cells and Responsiveness to CSF1 Administration

(2014) Kristin A. Sauter et al.   PLoS One

A close look at brain dynamics: Cells and vessels seen by in vivo two-photon microscopy

(2014) Stefano Fumagalli et al.   PROGRESS IN NEUROBIOLOGY

The multiple faces of leukocyte interstitial migration

(2014) Tim Lämmermann et al.   Seminars in Immunopathology

Tracking and quantification of dendritic cell migration and antigen trafficking between the skin and lymph nodes

(2014) Michio Tomura et al.   Scientific Reports

Dynamic imaging reveals promiscuous crosspresentation of blood-borne antigens to naive CD8+ T cells in the bone marrow

(2013) I. Milo et al.   BLOOD

CX3CR1 reduces Ly6Chigh-monocyte motility within and release from the bone marrow after chemotherapy in mice

(2013) S. Jacquelin et al.   BLOOD

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

Neutrophils Recruited to Sites of Infection Protect from Virus Challenge by Releasing Neutrophil Extracellular Traps

(2013) Craig N. Jenne et al.   Cell Host & Microbe

Endoscopic Time-Lapse Imaging of Immune Cells in Infarcted Mouse Hearts

(2013) Keehoon Jung et al.   CIRCULATION RESEARCH

High-Resolution Imaging of Intravascular Atherogenic Inflammation in Live Mice

(2013) Raphael Chèvre et al.   CIRCULATION RESEARCH

Reporter Mouse Lines for Fluorescence Imaging

(2013) Takaya Abe et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Quantitative dynamic footprinting microscopy

(2013) Prithu Sundd et al.   IMMUNOLOGY AND CELL BIOLOGY

LC–MS/MS method for rapid and concomitant quantification of pro-inflammatory and pro-resolving polyunsaturated fatty acid metabolites

(2013) Pauline Le Faouder et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival

(2013) Michail S. Lionakis et al.   JOURNAL OF CLINICAL INVESTIGATION

Extravascular CX3CR1+ Cells Extend Intravascular Dendritic Processes into Intact Central Nervous System Vessel Lumen

(2013) Deborah S. Barkauskas et al.   MICROSCOPY AND MICROANALYSIS

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

(2013) Tim Lämmermann et al.   NATURE

Automated Filtering of Intrinsic Movement Artifacts during Two-Photon Intravital Microscopy

(2013) Denis Soulet et al.   PLoS One

Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

(2013) Grietje Krabbe et al.   PLoS One

Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging

(2013) Claudio Vinegoni et al.   Biomedical Optics Express

From seeing to believing: labelling strategies for in vivo cell-tracking experiments

(2013) F. Progatzky et al.   Interface Focus

Plaque-Associated Vasa Vasorum in Aged Apolipoprotein E–Deficient Mice Exhibit Proatherogenic Functional Features In Vivo

(2012) Timo Rademakers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

An improved intracellular staining protocol for efficient detection of nuclear proteins in YFP-expressing cells

(2012) Maria Grupillo et al.   BIOTECHNIQUES

Histo-Cytometry: A Method for Highly Multiplex Quantitative Tissue Imaging Analysis Applied to Dendritic Cell Subset Microanatomy in Lymph Nodes

(2012) Michael Y. Gerner et al.   IMMUNITY

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Improved intravital microscopy via synchronization of respiration and holder stabilization

(2012) Sungon Lee et al.   JOURNAL OF BIOMEDICAL OPTICS

Real-time interactive two-photon photoconversion of recirculating lymphocytes for discontinuous cell tracking in live adult mice

(2012) Tatyana Chtanova et al.   Journal of Biophotonics

Intravital 2-photon imaging of leukocyte trafficking in beating heart

(2012) Wenjun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamic T cell–APC interactions sustain chronic inflammation in atherosclerosis

(2012) Ekaterina K. Koltsova et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of a MHC I-restricted epitope of DsRed in C57BL/6 mice

(2012) Gayle M. Davey et al.   MOLECULAR IMMUNOLOGY

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

(2012) Jeremiah R. McDole et al.   NATURE

Body-barrier surveillance by epidermal γδ TCRs

(2012) Grzegorz Chodaczek et al.   NATURE IMMUNOLOGY

Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs

(2012) Konstantin Stark et al.   NATURE IMMUNOLOGY

Intravital multiphoton imaging of immune responses in the mouse ear skin

(2012) Jackson LiangYao Li et al.   Nature Protocols

Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos

(2012) Tomomasa Yokomizo et al.   Nature Protocols

Regulation of gene expression in atherosclerosis: insights from microarray studies in monocytes/macrophages

(2012) Juan C Laguna et al.   PHARMACOGENOMICS

Quantitative Analysis of Monocyte Subpopulations in Murine Atherosclerotic Plaques by Multiphoton Microscopy

(2012) Abigail S. Haka et al.   PLoS One

A Decade of Imaging Cellular Motility and Interaction Dynamics in the Immune System

(2012) R. N. Germain et al.   SCIENCE

PKH26 Can Transfer to Host Cells In Vitro and Vivo

(2012) Peng Li et al.   STEM CELLS AND DEVELOPMENT

Real-time in vivo imaging of the beating mouse heart at microscopic resolution

(2012) Sungon Lee et al.   Nature Communications

Adipose lineage specification of bone marrow-derived myeloid cells

(2012) Susan M. Majka et al.   Adipocyte

Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas

(2011) Jackson G. Egen et al.   IMMUNITY

Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe–/– mice during disease regression

(2011) Stephane Potteaux et al.   JOURNAL OF CLINICAL INVESTIGATION

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Intravital imaging of phagocyte recruitment

(2011) Klaus Kemmerich et al.   THROMBOSIS AND HAEMOSTASIS

HMGB1 inhibits macrophage activity in efferocytosis through binding to the αvβ3-integrin

(2010) Arnaud Friggeri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Expanding Two-Photon Intravital Microscopy to the Infrared by Means of Optical Parametric Oscillator

(2010) Josephine Herz et al.   BIOPHYSICAL JOURNAL

"Microenvironmental contaminations" induced by fluorescent lipophilic dyes used for noninvasive in vitro and in vivo cell tracking

(2010) F. Lassailly et al.   BLOOD

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Hyperlipidemia-Triggered Neutrophilia Promotes Early Atherosclerosis

(2010) Maik Drechsler et al.   CIRCULATION

Evaluation of foam cell formation in cultured macrophages: an improved method with Oil Red O staining and DiI-oxLDL uptake

(2010) Suowen Xu et al.   CYTOTECHNOLOGY

In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy

(2010) Remco T. A. Megens et al.   JOURNAL OF BIOMEDICAL OPTICS

CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung

(2010) Cyrille Mionnet et al.   NATURE MEDICINE

Stabilized imaging of immune surveillance in the mouse lung

(2010) Mark R Looney et al.   NATURE METHODS

Imaging leukocyte trafficking in vivo with two-photon-excited endogenous tryptophan fluorescence

(2010) Chunqiang Li et al.   OPTICS EXPRESS

Fluorescent Proteins and Their Applications in Imaging Living Cells and Tissues

(2010) Dmitriy M. Chudakov et al.   PHYSIOLOGICAL REVIEWS

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

A Novel Technique for the In Vivo Imaging of Autoimmune Diabetes Development in the Pancreas by Two-Photon Microscopy

(2010) Ken Coppieters et al.   PLoS One

CX3CR1+ CD8 + dendritic cells are a steady-state population related to plasmacytoid dendritic cells

(2010) L. Bar-On et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravital imaging of anti-tumor immune response and the tumor microenvironment

(2010) Tomasz Zal et al.   Seminars in Immunopathology

A Thin-skull Window Technique for Chronic Two-photon In vivo Imaging of Murine Microglia in Models of Neuroinflammation

(2010) Daniel F. Marker et al.   Jove-Journal of Visualized Experiments

Assessment of lymphocyte proliferation: CFSE kills dividing cells and modulates expression of activation markers

(2009) J. Lašt’ovička et al.   CELLULAR IMMUNOLOGY

GFP-p65 knock-in mice as a tool to study NF-κB dynamics in vivo

(2009) Rossana De Lorenzi et al.   GENESIS

Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions

(2009) Chen Varol et al.   IMMUNITY

Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves

(2009) Jae-Hoon Choi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peak Multiphoton Excitation of mCherry Using an Optical Parametric Oscillator (OPO)

(2009) Tegy J. Vadakkan et al.   JOURNAL OF FLUORESCENCE

Deep tissue multiphoton microscopy using longer wavelength excitation

(2009) Demirhan Kobat et al.   OPTICS EXPRESS

In Vivo Transfer of Intracellular Labels from Locally Implanted Bone Marrow Stromal Cells to Resident Tissue Macrophages

(2009) Edyta Pawelczyk et al.   PLoS One

Inflammation and Proliferation Act Together to Mediate Intestinal Cell Fusion

(2009) Paige S. Davies et al.   PLoS One

In Vivo Analysis of Dendritic Cell Development and Homeostasis

(2009) K. Liu et al.   SCIENCE

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

Choreography of Cell Motility and Interaction Dynamics Imaged by Two-Photon Microscopy in Lymphoid Organs

(2008) Michael D. Cahalan et al.   Annual Review of Immunology

CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival

(2008) L. Landsman et al.   BLOOD

Cell tracking with optical imaging

(2008) Elizabeth J. Sutton et al.   EUROPEAN RADIOLOGY

Macrophage and T Cell Dynamics during the Development and Disintegration of Mycobacterial Granulomas

(2008) Jackson G. Egen et al.   IMMUNITY

Video-rate two-photon imaging of mouse footpad – a promising model for studying leukocyte recruitment dynamics during inflammation

(2008) B. H. Zinselmeyer et al.   INFLAMMATION RESEARCH

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

(2008) Jiyun V. Kim et al.   NATURE

Improvement of reporter activity by IRES-mediated polycistronic reporter system

(2008) H. Bouabe et al.   NUCLEIC ACIDS RESEARCH

Monitoring cellular movement in vivo with photoconvertible fluorescence protein "Kaede" transgenic mice

(2008) M. Tomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies

(2008) N. C. Peters et al.   SCIENCE