The Use of Artificial Sputum Media to Enhance Investigation and Subsequent Treatment of Cystic Fibrosis Bacterial Infections

Bacterial biofilms predominate in both acute and chronic human lung infections

(2022) Mette Kolpen et al.   THORAX

Impact of artificial sputum media formulation on Pseudomonas aeruginosa secondary metabolite production

(2021) Rachel L. Neve et al.   JOURNAL OF BACTERIOLOGY

Effect of N-Acetylcysteine in Combination with Antibiotics on the Biofilms of Three Cystic Fibrosis Pathogens of Emerging Importance

(2021) Aditi Aiyer et al.   Antibiotics-Basel

Evaluation of anti-biofilm activity of acidic amino acids and synergy with ciprofloxacin on Staphylococcus aureus biofilms

(2020) Annsar A. Warraich et al.   Scientific Reports

Modelling experimentally measured of ciprofloxacin antibiotic diffusion in Pseudomonas aeruginosa biofilm formed in artificial sputum medium

(2020) Tadeusz Kosztołowicz et al.   PLoS One

Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients

(2019) La Rosa et al.   Metabolites

Mucus-penetrating solid lipid nanoparticles for the treatment of cystic fibrosis: Proof of concept, challenges and pitfalls

(2018) N. Nafee et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The Consequences of Biofilm Dispersal on the Host

(2018) Derek Fleming et al.   Scientific Reports

Cystic Fibrosis 2017—The Year in Review

(2017) Bruce K Rubin   Respiratory Care

Iron Acquisition Mechanisms and Their Role in the Virulence of Burkholderia Species

(2017) Aaron T. Butt et al.   Frontiers in Cellular and Infection Microbiology

Glutathione-Disrupted Biofilms of Clinical Pseudomonas aeruginosa Strains Exhibit an Enhanced Antibiotic Effect and a Novel Biofilm Transcriptome

(2016) William Klare et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A novel method for investigating Burkholderia cenocepacia infections in patients with cystic fibrosis and other chronic diseases of the airways

(2016) Christiaan D. M. Wijers et al.   BMC MICROBIOLOGY

Cystic fibrosis

(2016) J Stuart Elborn   LANCET

Cystic Fibrosis

(2016) Edith T. Zemanick et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Cystic fibrosis lung environment and Pseudomonas aeruginosa infection

(2016) Anjali Y. Bhagirath et al.   BMC Pulmonary Medicine

Synthetic Cystic Fibrosis Sputum Medium Regulates Flagellar Biosynthesis through the flhF Gene in Burkholderia cenocepacia

(2016) Brijesh Kumar et al.   Frontiers in Cellular and Infection Microbiology

Mucin Binding Reduces Colistin Antimicrobial Activity

(2015) Johnny X. Huang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Erratum: A Winogradsky-based culture system shows an association between microbial fermentation and cystic fibrosis exacerbation

(2015) Robert A Quinn et al.   ISME Journal

Cystic fibrosis — From basic science to clinical benefit: A review series

(2015) Dominik Hartl et al.   Journal of Cystic Fibrosis

Relation between chemotaxis and consumption of amino acids in bacteria

(2015) Yiling Yang et al.   MOLECULAR MICROBIOLOGY

Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum

(2015) Keith H. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

D-Amino acids inhibit biofilm formation in Staphylococcus epidermidis strains from ocular infections

(2014) M. L. Ramon-Perez et al.   JOURNAL OF MEDICAL MICROBIOLOGY

An In Vitro Study on the Effect of Free Amino Acids Alone or in Combination with Nisin on Biofilms as well as on Planktonic Bacteria of Streptococcus mutans

(2014) Zhongchun Tong et al.   PLoS One

Characterization of biofilm-like structures formed by Pseudomonas aeruginosa in a synthetic mucus medium

(2012) Cecily L Haley et al.   BMC MICROBIOLOGY

Targeting iron uptake to controlPseudomonas aeruginosainfections in cystic fibrosis

(2012) Daniel J. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Use of Artificial Sputum Medium to Test Antibiotic Efficacy Against Pseudomonas aeruginosa in Conditions More Relevant to the Cystic Fibrosis Lung

(2012) Sebastian Kirchner et al.   Jove-Journal of Visualized Experiments

Proteomics of Pseudomonas aeruginosa Australian Epidemic Strain 1 (AES-1) Cultured under Conditions Mimicking the Cystic Fibrosis Lung Reveals Increased Iron Acquisition via the Siderophore Pyochelin

(2011) Nathan J. Hare et al.   JOURNAL OF PROTEOME RESEARCH

Pseudomonas aeruginosa AES-1 Exhibits Increased Virulence Gene Expression during Chronic Infection of Cystic Fibrosis Lung

(2011) Sharna Naughton et al.   PLoS One

The clinical impact of bacterial biofilms

(2011) Niels Høiby et al.   International Journal of Oral Science

Characterization of JG024, a pseudomonas aeruginosa PB1-like broad host range phage under simulated infection conditions

(2010) Julia Garbe et al.   BMC MICROBIOLOGY

Gene expression of Pseudomonas aeruginosa in a mucin-containing synthetic growth medium mimicking cystic fibrosis lung sputum

(2010) C. Fung et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Pharmacological correction of a defect in PPAR-γ signaling ameliorates disease severity in Cftr-deficient mice

(2010) Gregory S Harmon et al.   NATURE MEDICINE

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structure and Function of the Cell Surface (Tethered) Mucins

(2007) Christine L. Hattrup et al.   Annual Review of Physiology

Structure and Function of the Polymeric Mucins in Airways Mucus

(2007) David J. Thornton et al.   Annual Review of Physiology