Selective Upregulation of SIRT1 Expression in Retinal Ganglion Cells by AAV-Mediated Gene Delivery Increases Neuronal Cell Survival and Alleviates Axon Demyelination Associated with Optic Neuritis

CD38 deficiency protects the retina from ischaemia/reperfusion injury partly via suppression of TLR4/MyD88/NF-κB signalling

(2022) Guiping Chen et al.   EXPERIMENTAL EYE RESEARCH

The Role of Diet and Interventions on Multiple Sclerosis: A Review

(2022) Panagiotis Stoiloudis et al.   Nutrients

Remedial Effect of Intravenous Cyclophosphamide in Corticosteroid-Refractory Patients in the Acute Phase of Neuromyelitis Optica Spectrum Disorder-Related Optic Neuritis

(2021) Ling Wang et al.   Frontiers in Neurology

Rescue of retinal ganglion cells in optic nerve injury using cell-selective AAV mediated delivery of SIRT1

(2021) Ahmara G. Ross et al.   GENE THERAPY

Role of Silent Information Regulator 1 (SIRT1) in Regulating Oxidative Stress and Inflammation

(2020) Vivek Singh et al.   INFLAMMATION

Retinal Tropism and Transduction of Adeno-Associated Virus Varies by Serotype and Route of Delivery (Intravitreal, Subretinal, or Suprachoroidal) in Rats

(2020) Ian C. Han et al.   HUMAN GENE THERAPY

Comparative AAV-eGFP Transgene Expression Using Vector Serotypes 1–9, 7m8, and 8b in Human Pluripotent Stem Cells, RPEs, and Human and Rat Cortical Neurons

(2019) Thu T. Duong et al.   Stem Cells International

Critical review: Typical and atypical optic neuritis

(2019) Anne Abel et al.   SURVEY OF OPHTHALMOLOGY

Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study

(2018) Massimo Filippi et al.   LANCET NEUROLOGY

Intravitreal AAV-Delivery of Genetically Encoded Sensors Enabling Simultaneous Two-Photon Imaging and Electrophysiology of Optic Nerve Axons

(2018) Zoe J. Looser et al.   Frontiers in Cellular Neuroscience

Sirtuins in Neuroendocrine Regulation and Neurological Diseases

(2018) Yuki Fujita et al.   Frontiers in Neuroscience

Evaluation of Dose and Safety of AAV7m8 and AAV8BP2 in the Non-Human Primate Retina

(2017) Pavitra S. Ramachandran et al.   HUMAN GENE THERAPY

Intravitreous injection of AAV2-sFLT01 in patients with advanced neovascular age-related macular degeneration: a phase 1, open-label trial

(2017) Jeffrey S Heier et al.   LANCET

A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina

(2017) Antoine Chaffiol et al.   MOLECULAR THERAPY

Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial

(2016) Jean Bennett et al.   LANCET

2-Deoxy glucose regulate MMP-9 in a SIRT-1 dependent and NFkB independent mechanism

(2016) Lincy Edatt et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mangiferin Protects Retinal Ganglion Cells in Ischemic Mouse Retina via SIRT1

(2015) Soo-Jin Kim et al.   CURRENT EYE RESEARCH

SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1 

(2015) S.-H. Cho et al.   JOURNAL OF NEUROSCIENCE

Autophagy in axonal degeneration in glaucomatous optic neuropathy

(2015) Yasunari Munemasa et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Ligand-activated peroxisome proliferator-activated receptor-δ and -γ inhibit lipopolysaccharide-primed release of high mobility group box 1 through upregulation of SIRT1

(2014) J S Hwang et al.   Cell Death & Disease

The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina

(2013) Allen R. Rodriguez et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Protective effect of SIRT1 on toxicity of microglial-derived factors induced by LPS to PC12 cells via the p53-caspase-3-dependent apoptotic pathway

(2013) Jieming Ye et al.   NEUROSCIENCE LETTERS

Treatment of Optic Neuritis by Plasma Exchange (Add-On) in Neuromyelitis Optica

(2012) Harold Merle et al.   ARCHIVES OF OPHTHALMOLOGY

Treatment of neuromyelitis optica: an evidence based review

(2012) Douglas Sato et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE

(2012) Alison L. Christy et al.   JOURNAL OF AUTOIMMUNITY

SIRT1 activating compounds reduce oxidative stress and prevent cell death in neuronal cells

(2012) Reas S. Khan et al.   Frontiers in Cellular Neuroscience

Resveratrol Neuroprotection in a Chronic Mouse Model of Multiple Sclerosis

(2012) Zoe Fonseca-Kelly et al.   Frontiers in Neurology

Modulation of FoxO1 phosphorylation/acetylation by baicalin during aging

(2011) Dae Hyun Kim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Optic Neuritis and Retinal Ganglion Cell Loss in a Chronic Murine Model of Multiple Sclerosis

(2011) Thomas A. Quinn et al.   Frontiers in Neurology

SIRT1 modulates high-mobility group box 1-induced osteoclastogenic cytokines in human periodontal ligament cells

(2010) Young-Suk Kim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Oral Resveratrol Reduces Neuronal Damage in a Model of Multiple Sclerosis

(2010) Kenneth S Shindler et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Retinal Ganglion Cells Downregulate Gene Expression and Lose Their Axons within the Optic Nerve Head in a Mouse Glaucoma Model

(2008) I. Soto et al.   JOURNAL OF NEUROSCIENCE

Experimental Optic Neuritis Induced by a Demyelinating Strain of Mouse Hepatitis Virus

(2008) K. S. Shindler et al.   JOURNAL OF VIROLOGY