Mangiferin Protects Retinal Ganglion Cells in Ischemic Mouse Retina via SIRT1

SIRT1 inhibition by sirtinol aggravates brain edema after experimental subarachnoid hemorrhage

(2014) Xiao-Ming Zhou et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Sirtuin1 Over-Expression Does Not Impact Retinal Vascular and Neuronal Degeneration in a Mouse Model of Oxygen-Induced Retinopathy

(2014) Shaday Michan et al.   PLoS One

Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy

(2013) Jing Chen et al.   ANGIOGENESIS

Mangiferin mitigates diabetic cardiomyopathy in streptozotocin-diabetic rats

(2013) Jun Hou et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

Targeting Sirtuin-1 in Huntington’s Disease: Rationale and Current Status

(2013) Wenzhen Duan   CNS DRUGS

The Neuroprotective Effect of Carnosine (β-Alanyl-l-Histidine) on Retinal Ganglion Cell Following Ischemia-Reperfusion Injury

(2013) Yong-Sok Ji et al.   CURRENT EYE RESEARCH

Redox regulation of SIRT1 in inflammation and cellular senescence

(2013) Jae-woong Hwang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mangiferin from Salacia chinensis Prevents Oxidative Stress and Protects Pancreatic β-Cells in Streptozotocin-Induced Diabetic Rats

(2013) Periyar Selvam Sellamuthu et al.   JOURNAL OF MEDICINAL FOOD

Peroxisome Proliferator-Activated Receptor (PPAR) γ and PPARα Agonists Modulate Mitochondrial Fusion-Fission Dynamics: Relevance to Reactive Oxygen Species (ROS)-Related Neurodegenerative Disorders?

(2013) Juan M. Zolezzi et al.   PLoS One

Silent Information Regulator 1 Protects the Brain Against Cerebral Ischemic Damage

(2013) M. Hernandez-Jimenez et al.   STROKE

Natural polyphenols against neurodegenerative disorders: Potentials and pitfalls

(2012) Azadeh Ebrahimi et al.   AGEING RESEARCH REVIEWS

The secrets of the Bcl-2 family

(2012) A J García-Sáez   CELL DEATH AND DIFFERENTIATION

Oxidative stress and mitochondrial dysfunction in glaucoma

(2012) Vicki Chrysostomou et al.   CURRENT OPINION IN PHARMACOLOGY

Neuropharmacological effect of Mangiferin on brain cholinesterase and brain biogenic amines in the management of Alzheimer's disease

(2012) Siddaruda M. Biradar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Central roles of apoptotic proteins in mitochondrial function

(2012) S M Kilbride et al.   ONCOGENE

Brimonidine Blocks Glutamate Excitotoxicity-Induced Oxidative Stress and Preserves Mitochondrial Transcription Factor A in Ischemic Retinal Injury

(2012) Dongwook Lee et al.   PLoS One

SIRT1 activating compounds reduce oxidative stress and prevent cell death in neuronal cells

(2012) Reas S. Khan et al.   Frontiers in Cellular Neuroscience

Role of Sirtuins and Calorie Restriction in Neuroprotection: Implications in Alzheimers and Parkinsons Diseases

(2011) Sarika Srivastava et al.   CURRENT PHARMACEUTICAL DESIGN

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

Resveratrol Prevents Light-Induced Retinal Degeneration via Suppressing Activator Protein-1 Activation

(2010) Shunsuke Kubota et al.   AMERICAN JOURNAL OF PATHOLOGY

Hypoxia and mitochondrial oxidative metabolism

(2010) Giancarlo Solaini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Superoxide is an associated signal for apoptosis in axonal injury

(2010) A. Kanamori et al.   BRAIN

Mitochondria: Their role in ganglion cell death and survival in primary open angle glaucoma

(2010) Neville N. Osborne   EXPERIMENTAL EYE RESEARCH

SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

(2010) Samuel Caito et al.   FASEB JOURNAL

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

The effect of ginkgo biloba on the rat retinal ganglion cell survival in the optic nerve crush model

(2009) Ke Ma et al.   ACTA OPHTHALMOLOGICA

Molecular mechanisms of neuroprotection by two natural antioxidant polyphenols

(2009) María Rosario Campos-Esparza et al.   CELL CALCIUM

Mangifera indica L. extract attenuates glutamate-induced neurotoxicity on rat cortical neurons

(2009) Yeny Lemus-Molina et al.   NEUROTOXICOLOGY

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

Characterization and Quantitation of Polyphenolic Compounds in Bark, Kernel, Leaves, and Peel of Mango (Mangifera indicaL.)

(2008) Jacqueline C. Barreto et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effect of mangiferin on benzo(a)pyrene induced lung carcinogenesis in experimental Swiss albino mice

(2008) P. Rajendran et al.   NATURAL PRODUCT RESEARCH