Exploring TRPC3 Interaction with Cholesterol through Coarse-Grained Molecular Dynamics Simulations

Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state

(2022) Hazel Erkan‐Candag et al.   EMBO REPORTS

Steroids and TRP Channels: A Close Relationship

(2020) Karina Angélica Méndez-Reséndiz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Defining how multiple lipid species interact with inward rectifier potassium (Kir2) channels

(2020) Anna L. Duncan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid-protein interactions modulate the conformational equilibrium of a potassium channel

(2020) Ruo-Xu Gu et al.   Nature Communications

Computational Modeling of Realistic Cell Membranes

(2019) Siewert J. Marrink et al.   CHEMICAL REVIEWS

Emerging Diversity in Lipid–Protein Interactions

(2019) Valentina Corradi et al.   CHEMICAL REVIEWS

Membrane Protein–Lipid Interactions Probed Using Mass Spectrometry

(2019) Jani Reddy Bolla et al.   Annual Review of Biochemistry

Interfacial Binding Sites for Cholesterol on G Protein-Coupled Receptors

(2019) Anthony G. Lee   BIOPHYSICAL JOURNAL

Structural and Evolutionary Insights Point to Allosteric Regulation of TRP Ion Channels

(2019) Jacob K. Hilton et al.   ACCOUNTS OF CHEMICAL RESEARCH

Mass spectrometry—A versatile tool for characterising the lipid environment of membrane protein assemblies

(2019) Melissa Frick et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Interfacial Binding Sites for Cholesterol on TRP Ion Channels

(2019) Anthony G. Lee   BIOPHYSICAL JOURNAL

A Mass-Spectrometry-Based Approach to Distinguish Annular and Specific Lipid Binding to Membrane Proteins

(2019) Jani Reddy Bolla et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel

(2018) Michaela Lichtenegger et al.   Nature Chemical Biology

Structure of the human lipid-gated cation channel TRPC3

(2018) Chen Fan et al.   eLife

Lipid–Protein Interactions Are Unique Fingerprints for Membrane Proteins

(2018) Valentina Corradi et al.   ACS Central Science

Molecular Dynamics Simulations of Kir2.2 Interactions with an Ensemble of Cholesterol Molecules

(2018) Nicolas Barbera et al.   BIOPHYSICAL JOURNAL

TRPC3 as a Target of Novel Therapeutic Interventions

(2018) Oleksandra Tiapko et al.   Cells

GROmaρs: A GROMACS-Based Toolset to Analyze Density Maps Derived from Molecular Dynamics Simulations

(2018) Rodolfo Briones et al.   BIOPHYSICAL JOURNAL

Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor Smoothened

(2018) George Hedger et al.   STRUCTURE

The role of interfacial lipids in stabilizing membrane protein oligomers

(2017) Kallol Gupta et al.   NATURE

A mirror code for protein-cholesterol interactions in the two leaflets of biological membranes

(2016) Jacques Fantini et al.   Scientific Reports

The influence of cholesterol on membrane protein structure, function, and dynamics studied by molecular dynamics simulations

(2015) Julie Grouleff et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Computational Lipidomics with insane: A Versatile Tool for Generating Custom Membranes for Molecular Simulations

(2015) Tsjerk A. Wassenaar et al.   Journal of Chemical Theory and Computation

Lipid–protein interactions

(2015) Anthony G. Lee   BIOCHEMICAL SOCIETY TRANSACTIONS

Membrane proteins bind lipids selectively to modulate their structure and function

(2014) Arthur Laganowsky et al.   NATURE

Cholesterol binding to ion channels

(2014) Irena Levitan et al.   Frontiers in Physiology

Identification of Novel Cholesterol-binding Regions in Kir2 Channels

(2013) Avia Rosenhouse-Dantsker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol as a co-solvent and a ligand for membrane proteins

(2013) Yuanli Song et al.   PROTEIN SCIENCE

How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains

(2013) Jacques Fantini et al.   Frontiers in Physiology

Improved Parameters for the Martini Coarse-Grained Protein Force Field

(2012) Djurre H. de Jong et al.   Journal of Chemical Theory and Computation

MDAnalysis: A toolkit for the analysis of molecular dynamics simulations

(2011) Naveen Michaud-Agrawal et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

OPM database and PPM web server: resources for positioning of proteins in membranes

(2011) Mikhail A. Lomize et al.   NUCLEIC ACIDS RESEARCH

The transient receptor potential family of ion channels

(2011) Bernd Nilius et al.   GENOME BIOLOGY

Embedded cholesterol in the nicotinic acetylcholine receptor

(2008) G. Brannigan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA