Tuning Design Parameters of ICAM-1-Targeted 3DNA Nanocarriers to Optimize Pulmonary Targeting Depending on Drug Type

Polymeric Nanoparticles: Production, Characterization, Toxicology and Ecotoxicology

(2020) Aleksandra Zielińska et al.   MOLECULES

A Method to Improve Quantitative Radiotracing‐Based Analysis of the In Vivo Biodistribution of Drug Carriers

(2020) Nikša Roki et al.   Bioengineering & Translational Medicine

Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain

(2019) Oscar A. Marcos-Contreras et al.   JOURNAL OF CONTROLLED RELEASE

Unprecedently high targeting specificity toward lung ICAM-1 using 3DNA nanocarriers

(2019) Nikša Roki et al.   JOURNAL OF CONTROLLED RELEASE

Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain

(2019) Juliette Van Steenwinckel et al.   BRAIN

The effects of ligand valency and density on the targeting ability of multivalent nanoparticles based on negatively charged chitosan nanoparticles

(2018) Jing Cao et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape

(2018) Maartje M. C. Bastings et al.   NANO LETTERS

DNA Nanostructures at the Interface with Biology

(2018) Katherine E. Bujold et al.   Chem

Antibody-Conjugated, DNA-Based Nanocarriers Intercalated with Doxorubicin Eliminate Myofibroblasts in Explants of Human Lens Tissue

(2017) Jacquelyn Gerhart et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Enhanced Delivery and Effects of Acid Sphingomyelinase by ICAM-1-Targeted Nanocarriers in Type B Niemann-Pick Disease Mice

(2017) Carmen Garnacho et al.   MOLECULAR THERAPY

Influence of Polymer Size on Uptake and Cytotoxicity of Doxorubicin-Loaded DNA–PEG Conjugates

(2016) Laura Purdie et al.   BIOCONJUGATE CHEMISTRY

How Carrier Size and Valency Modulate Receptor-Mediated Signaling: Understanding the Link between Binding and Endocytosis of ICAM-1-Targeted Carriers

(2016) Daniel Serrano et al.   BIOMACROMOLECULES

Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth

(2016) Yu-Hung Huang et al.   CANCER RESEARCH

DNA-Based Drug Carriers: The Paradox of a Classical “Cargo” Material Becoming a Versatile “Carrier” to Overcome Barriers in Drug Delivery

(2016) Robert Getts et al.   CURRENT PHARMACEUTICAL DESIGN

Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

(2015) Umeharu Ohto et al.   NATURE

Abstract 700: Systemic administration of DNA nanoparticles containing the diphtheria toxin gene reduces pancreatic tumor load in mice

(2015) Janet A. Sawicki et al.   CANCER RESEARCH

A DNA Device that Mediates Selective Endosomal Escape and Intracellular Delivery of Drugs and Biologicals

(2014) Silvia Muro   ADVANCED FUNCTIONAL MATERIALS

Aptamer-Targeted DNA Nanostructures for Therapeutic Delivery

(2014) Phapanin Charoenphol et al.   MOLECULAR PHARMACEUTICS

Large-scale de novo DNA synthesis: technologies and applications

(2014) Sriram Kosuri et al.   NATURE METHODS

Role of size of drug delivery carriers for pulmonary and intravenous administration with emphasis on cancer therapeutics and lung-targeted drug delivery

(2014) Chetna Dhand et al.   RSC Advances

Biological Functionalization of Drug Delivery Carriers To Bypass Size Restrictions of Receptor-Mediated Endocytosis Independently from Receptor Targeting

(2013) Maria Ansar et al.   ACS Nano

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium

(2013) P. Kolhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody-Linked Spherical Nucleic Acids for Cellular Targeting

(2012) Ke Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Cellular Immunostimulation by CpG-Sequence-Coated DNA Origami Structures

(2011) Verena J. Schüller et al.   ACS Nano

Aptamer-Conjugated DNA Icosahedral Nanoparticles As a Carrier of Doxorubicin for Cancer Therapy

(2011) Microsugar Chang et al.   ACS Nano

Nanoparticle targeting using multivalent ligands: computer modeling

(2011) Shihu Wang et al.   Soft Matter

Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers

(2010) Andres J. Calderon et al.   JOURNAL OF CONTROLLED RELEASE

Non-natural nucleic acids for synthetic biology

(2009) Daniel H Appella   CURRENT OPINION IN CHEMICAL BIOLOGY

DNA Nanotubes as Combinatorial Vehicles for Cellular Delivery

(2008) SeungHyeon Ko et al.   BIOMACROMOLECULES

Delivery of Acid Sphingomyelinase in Normal and Niemann-Pick Disease Mice Using Intercellular Adhesion Molecule-1-Targeted Polymer Nanocarriers

(2008) C. Garnacho et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers

(2008) Silvia Muro et al.   MOLECULAR THERAPY

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA