Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain

Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human

(2019) Helen B. Stolp et al.   Frontiers in Physiology

Cognitive Outcomes of Children Born Extremely or Very Preterm Since the 1990s and Associated Risk Factors

(2018) E. Sabrina Twilhaar et al.   JAMA Pediatrics

Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury

(2018) Claire-Marie Rangon et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglia in neurodegeneration

(2018) Suzanne Hickman et al.   NATURE NEUROSCIENCE

Microglia and early brain development: An intimate journey

(2018) Morgane S. Thion et al.   SCIENCE

Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury

(2017) Lawrence R. Shiow et al.   GLIA

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Antibody-Conjugated, DNA-Based Nanocarriers Intercalated with Doxorubicin Eliminate Myofibroblasts in Explants of Human Lens Tissue

(2017) Jacquelyn Gerhart et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Endothelial Wnt/β-catenin signaling reduces immune cell infiltration in multiple sclerosis

(2017) Justin E. Lengfeld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulating the wnt signaling pathway with small molecules

(2017) Freddi Huan Tran et al.   PROTEIN SCIENCE

Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants

(2017) Michelle L. Krishnan et al.   Nature Communications

Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth

(2016) Yu-Hung Huang et al.   CANCER RESEARCH

Neurobehaviour at term-equivalent age and neurodevelopmental outcomes at 2 years in infants born moderate-to-late preterm

(2016) Alicia J Spittle et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Phenotypic clustering: a novel method for microglial morphology analysis

(2016) Franck Verdonk et al.   Journal of Neuroinflammation

Microglia-Induced Activation of Noncanonical Wnt Signaling Aggravates Neurodegeneration in Demyelinating Disorders

(2016) Takeshi Shimizu et al.   MOLECULAR AND CELLULAR BIOLOGY

Wnt signaling in cancer

(2016) T Zhan et al.   ONCOGENE

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia development follows a stepwise program to regulate brain homeostasis

(2016) O. Matcovitch-Natan et al.   SCIENCE

Microglia contact induces synapse formation in developing somatosensory cortex

(2016) Akiko Miyamoto et al.   Nature Communications

Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation

(2016) Chuntao Zhao et al.   Nature Communications

Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants

(2016) Michelle L. Krishnan et al.   Brain and Behavior

Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation

(2016) Bin Ma et al.   Frontiers in Immunology

Roles of microglia in brain development, tissue maintenance and repair

(2015) Mackenzie A. Michell-Robinson et al.   BRAIN

Thalamocortical Connectivity Predicts Cognition in Children Born Preterm

(2015) Gareth Ball et al.   CEREBRAL CORTEX

Canonical Wnt signaling in the oligodendroglial lineage-puzzles remain

(2015) Fuzheng Guo et al.   GLIA

Understanding multicellular function and disease with human tissue-specific networks

(2015) Casey S Greene et al.   NATURE GENETICS

The role of inflammation in perinatal brain injury

(2015) Henrik Hagberg et al.   Nature Reviews Neurology

Spatial and temporal aspects of Wnt signaling and planar cell polarity during vertebrate embryonic development

(2015) Sergei Y. Sokol   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

JAG: A Computational Tool to Evaluate the Role of Gene-Sets in Complex Traits

(2015) Esther Lips et al.   Genes

A DNA Device that Mediates Selective Endosomal Escape and Intracellular Delivery of Drugs and Biologicals

(2014) Silvia Muro   ADVANCED FUNCTIONAL MATERIALS

Brain injury in premature neonates: A primary cerebral dysmaturation disorder?

(2014) Stephen A. Back et al.   ANNALS OF NEUROLOGY

Oligodendrocyte-Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis

(2014) Tracy J. Yuen et al.   CELL

Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4

(2014) Chien-Hsiung Yu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Genetic and epigenetic fine mapping of causal autoimmune disease variants

(2014) Kyle Kai-How Farh et al.   NATURE

Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer

(2014) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Common Genetic Variants and Risk of Brain Injury After Preterm Birth

(2014) J. P. Boardman et al.   PEDIATRICS

Switch from Canonical to Noncanonical Wnt Signaling Mediates High Glucose-Induced Adipogenesis

(2014) Emily C. Keats et al.   STEM CELLS

Gadolinium chloride improves the course of TNBS and DSS-induced colitis through protecting against colonic mucosal inflammation

(2014) Chao Du et al.   Scientific Reports

Microglia Modulate Wiring of the Embryonic Forebrain

(2014) Paola Squarzoni et al.   Cell Reports

Preterm birth and structural brain alterations in early adulthood

(2014) Chiara Nosarti et al.   NeuroImage-Clinical

G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration

(2013) Vincent Degos et al.   ANNALS OF NEUROLOGY

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

(2013) Vibol Chhor et al.   BRAIN BEHAVIOR AND IMMUNITY

Failure of thyroid hormone treatment to prevent inflammation-induced white matter injury in the immature brain

(2013) Anne-Laure Schang et al.   BRAIN BEHAVIOR AND IMMUNITY

WNT-3A and WNT-5A counteract lipopolysaccharide-induced pro-inflammatory changes in mouse primary microglia

(2013) Carina Halleskog et al.   JOURNAL OF NEUROCHEMISTRY

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Diffusion magnetic resonance imaging in preterm brain injury

(2013) Anand S. Pandit et al.   NEURORADIOLOGY

Development of cortical microstructure in the preterm human brain

(2013) Gareth Ball et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt3a induces exosome secretion from primary cultured rat microglia

(2012) Claudie Hooper et al.   BMC NEUROSCIENCE

Long-Range Ca2+ Waves Transmit Brain-Damage Signals to Microglia

(2012) Dirk Sieger et al.   DEVELOPMENTAL CELL

Phenotyping primary human microglia: Tight regulation of LPS responsiveness

(2012) Jeroen Melief et al.   GLIA

Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation

(2012) Carina Halleskog et al.   Journal of Neuroinflammation

RETRACTED ARTICLE: Alteration of astrocytes and Wnt/β-catenin signaling in the frontal cortex of autistic subjects

(2012) Fujiang Cao et al.   Journal of Neuroinflammation

Microglial Reaction in Axonal Crossroads Is a Hallmark of Noncystic Periventricular White Matter Injury in Very Preterm Infants

(2012) Catherine Verney et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Stephen S Lim et al.   LANCET

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

(2012) Noël C. Derecki et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Microglia activation in the extremely preterm human brain

(2012) Veena Supramaniam et al.   PEDIATRIC RESEARCH

Neurological and developmental outcome in extremely preterm children born in England in 1995 and 2006: the EPICure studies

(2012) T. Moore et al.   BMJ-British Medical Journal

Histopathological correlates of magnetic resonance imaging-defined chronic perinatal white matter injury

(2011) Art Riddle et al.   ANNALS OF NEUROLOGY

Systemic inflammation disrupts the developmental program of white matter

(2011) Géraldine Favrais et al.   ANNALS OF NEUROLOGY

Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants

(2011) Joshua R. Buser et al.   ANNALS OF NEUROLOGY

Inflammation during fetal and neonatal life: Implications for neurologic and neuropsychiatric disease in children and adults

(2011) Henrik Hagberg et al.   ANNALS OF NEUROLOGY

Canonical Wnt Signalling Requires the BMP Pathway to Inhibit Oligodendrocyte Maturation

(2011) Keith Feigenson et al.   ASN Neuro

Decreasing Incidence and Severity of Cerebral Palsy in Prematurely Born Children

(2011) Ingrid C. van Haastert et al.   JOURNAL OF PEDIATRICS

Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia

(2011) E S Lips et al.   MOLECULAR PSYCHIATRY

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

(2011) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Preterm Birth and Attention-Deficit/Hyperactivity Disorder in Schoolchildren

(2011) K. Lindstrom et al.   PEDIATRICS

Infant Brain Atlases from Neonates to 1- and 2-Year-Olds

(2011) Feng Shi et al.   PLoS One

A New Paradigm for Aptamer Therapeutic AS1411 Action: Uptake by Macropinocytosis and Its Stimulation by a Nucleolin-Dependent Mechanism

(2010) E. M. Reyes-Reyes et al.   CANCER RESEARCH

WNT signaling in activated microglia is proinflammatory

(2010) Carina Halleskog et al.   GLIA

Early microglial colonization of the human forebrain and possible involvement in periventricular white-matter injury of preterm infants

(2010) Catherine Verney et al.   JOURNAL OF ANATOMY

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

An optimised tract-based spatial statistics protocol for neonates: Applications to prematurity and chronic lung disease

(2010) Gareth Ball et al.   NEUROIMAGE

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

(2010) David Warde-Farley et al.   NUCLEIC ACIDS RESEARCH

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Wnt signaling is sufficient to perturb oligodendrocyte maturation

(2009) Keith Feigenson et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Behavioral Problems and Cognitive Performance at 5 Years of Age After Very Preterm Birth: The EPIPAGE Study

(2009) M. Delobel-Ayoub et al.   PEDIATRICS

Predicting Motor Development in Very Preterm Infants at 12 Months' Corrected Age: The Role of Qualitative Magnetic Resonance Imaging and General Movements Assessments

(2009) A. J. Spittle et al.   PEDIATRICS

Subclinical Histologic Chorioamnionitis and Related Clinical and Laboratory Parameters in Preterm Deliveries

(2009) Hui-Chung Wu et al.   Pediatrics and Neonatology

The Encephalopathy of Prematurity—Brain Injury and Impaired Brain Development Inextricably Intertwined

(2009) Joseph J. Volpe   Seminars in Pediatric Neurology

Role of microglial IKKβ in kainic acid-induced hippocampal neuronal cell death

(2008) Ik-Hyun Cho et al.   BRAIN

RESEARCH ARTICLE: Myelin Abnormalities without Oligodendrocyte Loss in Periventricular Leukomalacia

(2008) Saraid S. Billiards et al.   BRAIN PATHOLOGY

Adverse Neurodevelopment in Preterm Infants with Postnatal Sepsis or Necrotizing Enterocolitis is Mediated by White Matter Abnormalities on Magnetic Resonance Imaging at Term

(2008) Divyen K. Shah et al.   JOURNAL OF PEDIATRICS

Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances

(2008) Joseph J Volpe   LANCET NEUROLOGY

Diffuse Axonal Injury in Periventricular Leukomalacia as Determined by Apoptotic Marker Fractin

(2008) Robin L Haynes et al.   PEDIATRIC RESEARCH

Alternative Wnt Signaling Is Initiated by Distinct Receptors

(2008) R. van Amerongen et al.   Science Signaling