Design of an L-Valine-Modified Nanomicelle-Based Drug Delivery System for Overcoming Ocular Surface Barriers

Rational design of mixed nanomicelle eye drops with structural integrity investigation

(2022) Liping Sun et al.   Acta Biomaterialia

Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model

(2022) Liyu Chen et al.   Theranostics

Dry eye disease, a prominent manifestation of systemic autoimmune disorders

(2022) Andres Bustamante-Arias et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

Synthesis and characterization of Zinc(II) complex with ONO donor type new phenylpropanehydrazide based ligand: Crystal structure, Hirshfeld surface analysis, DFT, energy frameworks and molecular docking

(2022) M.N. Somashekar et al.   JOURNAL OF MOLECULAR STRUCTURE

Porcine Deltacoronavirus (PDCoV) Entry into PK-15 Cells by Caveolae-Mediated Endocytosis

(2022) Shiqian Li et al.   Viruses-Basel

Liver-Targeted Nanoparticles Facilitate the Bioavailability and Anti-HBV Efficacy of Baicalin In Vitro and In Vivo

(2022) Weiming Xu et al.   Biomedicines

Efficient antiglioblastoma therapy in mice through doxorubicin-loaded nanomicelles modified using a novel brain-targeted RVG-15 peptide

(2021) Mingfeng Han et al.   JOURNAL OF DRUG TARGETING

Topical Delivery of Levocarnitine to the Cornea and Anterior Eye by Thermosensitive in-situ Gel for Dry Eye Disease

(2021) Baorui Ma et al.   Drug Design Development and Therapy

Increased Water-Solubility and Maintained Antioxidant Power of Resveratrol by Its Encapsulation in Vitamin E TPGS Micelles: A Potential Nutritional Supplement for Chronic Liver Disease

(2021) Guendalina Zuccari et al.   Pharmaceutics

Rod-shaped nintedanib nanocrystals improved oral bioavailability through multiple intestinal absorption pathways

(2021) Yunjing Zhu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Design, development, in silico and in vitro characterization of Docetaxel-loaded TPGS/ Pluronic F 108 mixed micelles for improved cancer treatment

(2021) Kiran S. Patil et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

A review on nanotechnology: Properties, applications, and mechanistic insights of cellular uptake mechanisms

(2021) Salman Khan et al.   JOURNAL OF MOLECULAR LIQUIDS

Multifunctional carboxymethyl chitosan derivatives-layered double hydroxide hybrid nanocomposites for efficient drug delivery to the posterior segment of the eye

(2020) Yanyan Wang et al.   Acta Biomaterialia

Prodrugs and nanomicelles to overcome ocular barriers for drug penetration

(2020) Vrinda Gote et al.   Expert Opinion on Drug Metabolism & Toxicology

Pharmacokinetics of gemcitabine and its amino acid ester prodrug following intravenous and oral administrations in mice

(2020) Brian R. Thompson et al.   BIOCHEMICAL PHARMACOLOGY

Drug-integrating amphiphilic nanomaterial assemblies: 1. Spatiotemporal control of cyclosporine delivery and activity using nanomicelles and nanofibrils

(2020) Diana Velluto et al.   JOURNAL OF CONTROLLED RELEASE

Transporter-Targeted Nano-Sized Vehicles for Enhanced and Site-Specific Drug Delivery

(2020) Longfa Kou et al.   Cancers

The Role of Surface Active Agents in Ophthalmic Drug Delivery: A Comprehensive Review

(2019) Shaimaa S. Ibrahim   JOURNAL OF PHARMACEUTICAL SCIENCES

Multifunctional Nanocomposites Based on Liposomes and Layered Double Hydroxides Conjugated with Glycylsarcosine for Efficient Topical Drug Delivery to the Posterior Segment of the Eye

(2019) Yan Gu et al.   MOLECULAR PHARMACEUTICS

Exploring molecular dynamics simulation to predict binding with ocular mucin: An in silico approach for screening mucoadhesive materials for ocular retentive delivery systems

(2019) Rohan V. Pai et al.   JOURNAL OF CONTROLLED RELEASE

Characteristics and Risk Factors Associated With Diagnosed and Undiagnosed Symptomatic Dry Eye Using a Smartphone Application

(2019) Takenori Inomata et al.   JAMA Ophthalmology

Functional chitosan oligosaccharide nanomicelles for topical ocular drug delivery of dexamethasone

(2019) Xiaoyue Xu et al.   CARBOHYDRATE POLYMERS

A Novel Gel-Forming Solution Based on PEG-DSPE/Solutol HS 15 Mixed Micelles and Gellan Gum for Ophthalmic Delivery of Curcumin

(2019) Na Sai et al.   MOLECULES

The role of mucus on drug transport and its potential to affect therapeutic outcomes

(2018) Xabier Murgia et al.   ADVANCED DRUG DELIVERY REVIEWS

Baicalin modulates the Treg/Teff balance to alleviate uveitis by activating the aryl hydrocarbon receptor

(2018) Wenjie Zhu et al.   BIOCHEMICAL PHARMACOLOGY

In vitro stabilization and in vivo improvement of ocular pharmacokinetics of the multi-therapeutic agent baicalin: Delineating the most suitable vesicular systems

(2018) Orchid Ashraf et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effects of environment pollution on the ocular surface

(2018) Se Ji Jung et al.   Ocular Surface

Ocular Drug Delivery Barriers—Role of Nanocarriers in the Treatment of Anterior Segment Ocular Diseases

(2018) Rinda Bachu et al.   Pharmaceutics

Water extract of indoor dust induces tight junction disruption in normal human corneal epithelial cells

(2018) Ping Xiang et al.   ENVIRONMENTAL POLLUTION

Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders

(2017) Biswanath Dinda et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Multifunctional organic–inorganic hybrid nanoparticles and nanosheets based on chitosan derivative and layered double hydroxide: cellular uptake mechanism and application for topical ocular drug delivery

(2017) Huibo Chi et al.   International Journal of Nanomedicine

Designing lipid nanoparticles for topical ocular drug delivery

(2017) Jesus Alvarez-Trabado et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Self-targeted salinomycin-loaded DSPE-PEG-methotrexate nanomicelles for targeting both head and neck squamous cell carcinoma cancer cells and cancer stem cells

(2017) Minhui Zhu et al.   Nanomedicine

Cytotoxicity of CdTe quantum dots in human umbilical vein endothelial cells: the involvement of cellular uptake and induction of pro-apoptotic endoplasmic reticulum stress

(2016) Ming Yan et al.   International Journal of Nanomedicine

Improved oral bioavailability and anticancer efficacy on breast cancer of paclitaxel via Novel Soluplus ® —Solutol ® HS15 binary mixed micelles system

(2016) Jian Hou et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Lifitegrast, a Novel Integrin Antagonist for Treatment of Dry Eye Disease

(2016) Victor L. Perez et al.   Ocular Surface

iRGD-conjugated DSPE-PEG2000 nanomicelles for targeted delivery of salinomycin for treatment of both liver cancer cells and cancer stem cells

(2015) Xiaoli Mao et al.   Nanomedicine

Barrier Function in the Ocular Surface: From Conventional Paradigms to New Opportunities

(2015) Yuan-Yuh Leong et al.   Ocular Surface

Potential Therapeutic Effects of Baicalein, Baicalin, and Wogonin in Ocular Disorders

(2014) Jing-Ru Xiao et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Combined use of phospholipid complexes and self-emulsifying microemulsions for improving the oral absorption of a BCS class IV compound, baicalin

(2014) Huiyi Wu et al.   Acta Pharmaceutica Sinica B

Amino acids as promoieties in prodrug design and development

(2012) Balvinder S. Vig et al.   ADVANCED DRUG DELIVERY REVIEWS

Osmolality and tear film dynamics

(2011) Ulrike Stahl et al.   Clinical and Experimental Optometry

Drug Transporter and Cytochrome P450 mRNA Expression in Human Ocular Barriers: Implications for Ocular Drug Disposition

(2008) T. Zhang et al.   DRUG METABOLISM AND DISPOSITION