Integrated Analysis Reveals S100a8/a9 Regulates Autophagy and Apoptosis through the MAPK and PI3K-AKT Signaling Pathway in the Early Stage of Myocardial Infarction

Short-Term Blockade of Pro-Inflammatory Alarmin S100A9 Favorably Modulates Left Ventricle Proteome and Related Signaling Pathways Involved in Post-Myocardial Infarction Recovery

(2022) Raluca Maria Boteanu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anemoside B4 ameliorates TNBS-induced colitis through S100A9/MAPK/NF-κB signaling pathway

(2021) Yong Zhang et al.   Chinese Medicine

Neutrophil-Derived Protein S100A8/A9 Alters the Platelet Proteome in Acute Myocardial Infarction and Is Associated With Changes in Platelet Reactivity

(2021) Abhishek Joshi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

S100A9 Increases IL-6 and RANKL Expressions through MAPKs and STAT3 Signaling Pathways in Osteocyte-Like Cells

(2020) Ryosuke Takagi et al.   Biomed Research International

S100A9 Links Inflammation and Repair in Myocardial Infarction

(2020) Goran Marinković et al.   CIRCULATION RESEARCH

Serum alarmin S100A8/S100A9 levels and its potential role as biomarker in myocarditis

(2020) Irene Müller et al.   ESC Heart Failure

Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury

(2020) Tomohiro Yokota et al.   CELL

Identification and Validation of Stage-Associated PBMC Biomarkers in Breast Cancer Using MS-Based Proteomics

(2020) Raheleh Moradpoor et al.   Frontiers in Oncology

Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction

(2020) Ehsan Vafadarnejad et al.   CIRCULATION RESEARCH

Inflammation and fibrosis in murine models of heart failure

(2019) Lucas Bacmeister et al.   BASIC RESEARCH IN CARDIOLOGY

Fungal homologues of human Rac1 as emerging players in signal transduction and morphogenesis

(2019) Julia Hühn et al.   INTERNATIONAL MICROBIOLOGY

S100a8/a9 Signaling Causes Mitochondrial Dysfunction and Cardiomyocytes Death in Response Ischemic/Reperfusion Injury

(2019) Yulin Li et al.   CIRCULATION

S100 proteins in atherosclerosis

(2019) Xuan Xiao et al.   CLINICA CHIMICA ACTA

Rapamycin regulates the balance between�cardiomyocyte apoptosis and autophagy in chronic heart failure by inhibiting mTOR signaling

(2019) Guangyuan Gao et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Matrine inhibits the development and progression of ovarian cancer by repressing cancer associated phosphorylation signaling pathways

(2019) Xi Zhang et al.   Cell Death & Disease

Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway

(2019) Jin Zhou et al.   CELL PROLIFERATION

Autophagy in Human Health and Disease: Novel Therapeutic Opportunities

(2018) Francesca Giampieri et al.   ANTIOXIDANTS & REDOX SIGNALING

Deacetylmycoepoxydiene is an agonist of Rac1, and simultaneously induces autophagy and apoptosis

(2018) Wei Xie et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Single-Cell Transcriptome Analyses Reveal Endothelial Cell Heterogeneity in Tumors and Changes following Antiangiogenic Treatment

(2018) Qi Zhao et al.   CANCER RESEARCH

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation

(2018) Monika M. Gladka et al.   CIRCULATION

Trehalose-Induced Activation of Autophagy Improves Cardiac Remodeling After Myocardial Infarction

(2018) Sebastiano Sciarretta et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Therapeutic approaches for cardiac regeneration and repair

(2018) Hisayuki Hashimoto et al.   Nature Reviews Cardiology

Inflammation, Autophagy, and Apoptosis After Myocardial Infarction

(2018) Xianwei Wang et al.   Journal of the American Heart Association

Knockdown of lncRNA AK139328 alleviates myocardial ischaemia/reperfusion injury in diabetic mice via modulating miR-204-3p and inhibiting autophagy

(2018) Si-yang Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Boosting mTOR-dependent autophagy via upstream TLR4-MyD88-MAPK signalling and downstream NF-κB pathway quenches intestinal inflammation and oxidative stress injury

(2018) Mingxia Zhou et al.   EBioMedicine

Myocardial stress and autophagy: mechanisms and potential therapies

(2017) Lea M. D. Delbridge et al.   Nature Reviews Cardiology

Relationship Between Infarct Size and Outcomes Following Primary PCI

(2016) Gregg W. Stone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Relevance of mouse models of cardiac fibrosis and hypertrophy in cardiac research

(2016) Vikrant Rai et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Autophagy: a druggable process that is deregulated in aging and human disease

(2015) Guido Kroemer   JOURNAL OF CLINICAL INVESTIGATION

S100A9-induced release of interleukin (IL)-6 and IL-8 through toll-like receptor 4 (TLR4) in human periodontal ligament cells

(2015) Hongyu Gao et al.   MOLECULAR IMMUNOLOGY

S100A8 Contributes to Drug Resistance by Promoting Autophagy in Leukemia Cells

(2014) Minghua Yang et al.   PLoS One

The pathogenesis of cardiac fibrosis

(2013) Ping Kong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

TNFα- and IL-17A-mediated S100A8 expression is regulated by p38 MAPK

(2013) Maike Mose et al.   EXPERIMENTAL DERMATOLOGY

S100A8 and S100A9 promotes invasion and migration through p38 mitogen-activated protein kinase-dependent NF-κB activation in gastric cancer cells

(2013) Chae Hwa Kwon et al.   MOLECULES AND CELLS

Regulation of the Inflammatory Response in Cardiac Repair

(2012) Nikolaos G. Frangogiannis   CIRCULATION RESEARCH

Pex3-anchored Atg36 tags peroxisomes for degradation inSaccharomyces cerevisiae

(2012) Alison M Motley et al.   EMBO JOURNAL

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

Primary Angioplasty Versus Fibrinolysis in Acute Myocardial Infarction

(2010) Peter H. Nielsen et al.   CIRCULATION

S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3

(2009) Saeid Ghavami et al.   CELL RESEARCH

Activated cell survival cascade protects cardiomyocytes from cell death in Tako-Tsubo cardiomyopathy

(2009) Holger M. Nef et al.   EUROPEAN JOURNAL OF HEART FAILURE

S100A8 and S100A9 Mediate Endotoxin-Induced Cardiomyocyte Dysfunction via the Receptor for Advanced Glycation End Products

(2008) John H. Boyd et al.   CIRCULATION RESEARCH

Increased serum levels and expression of S100A8/A9 complex in infiltrated neutrophils in atherosclerotic plaque of unstable angina

(2008) S Miyamoto et al.   HEART