Lifting the Veil: Characteristics, Clinical Significance, and Application of β-2-Microglobulin as Biomarkers and Its Detection with Biosensors
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Title
Lifting the Veil: Characteristics, Clinical Significance, and Application of β-2-Microglobulin as Biomarkers and Its Detection with Biosensors
Authors
Keywords
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Journal
ACS Biomaterials-Science & Engineering
Volume 8, Issue 8, Pages 3142-3161
Publisher
American Chemical Society (ACS)
Online
2022-07-18
DOI
10.1021/acsbiomaterials.2c00036
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Note: Only part of the references are listed.- High-Throughput, High-Multiplex Digital Protein Detection with Attomolar Sensitivity
- (2022) Connie Wu et al. ACS Nano
- Association of beta-2-microglobulin and cardiovascular events and mortality: A systematic review and meta-analysis
- (2021) Fanchao Shi et al. ATHEROSCLEROSIS
- Computational Evolution of Beta-2-Microglobulin Binding Peptides for Nanopatterned Surface Sensors
- (2021) Abimbola Feyisara Adedeji Olulana et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2021) Shimrit Tzvi-Behr et al. PEDIATRIC NEPHROLOGY
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- (2021) Ming-Qi Liu et al. NEUROLOGICAL SCIENCES
- B2M overexpression correlates with malignancy and immune signatures in human gliomas
- (2021) Hao Zhang et al. Scientific Reports
- Urinary beta-2 microglobulin as an early predictive biomarker of acute kidney injury in neonates with perinatal asphyxia
- (2021) Abdullah et al. EUROPEAN JOURNAL OF PEDIATRICS
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- (2021) Kristell Mahe et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Prognostic Role of Beta-2 Microglobulin in Patients with Light Chain Amyloidosis Treated with Autologous Stem Cell Transplantation
- (2020) Abdullah S. Al Saleh et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Multiplexed MRM-based protein quantification of putative prognostic biomarkers for chronic kidney disease progression in plasma
- (2020) Manousos Makridakis et al. Scientific Reports
- Relationship between urinary β 2 ‐microglobulin concentration and mortality in a cadmium‐polluted area in Japan: A 35‐year follow‐up study
- (2020) Masaru Sakurai et al. JOURNAL OF APPLIED TOXICOLOGY
- Ultrasensitive Detection of Attomolar Protein Concentrations by Dropcast Single Molecule Assays
- (2020) Connie Wu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Microfluidic Immunosensor for Point-of-Care-Testing of Beta-2-Microglobulin in Tear
- (2020) Surjendu Maity et al. ACS Sustainable Chemistry & Engineering
- Recent Trends in Nanomaterial-Based Biosensors for Point-of-Care Testing
- (2020) Xu Wang et al. Frontiers in Chemistry
- The Early Phase of β2-Microglobulin Aggregation: Perspectives From Molecular Simulations
- (2020) Rui J. S. Loureiro et al. Frontiers in Molecular Biosciences
- New Potential Biomarkers for Chronic Kidney Disease Management—A Review of the Literature
- (2020) Irina Lousa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State
- (2019) Lorenzo Visconti et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Attomolar Label-Free Detection of DNA Hybridization with Electrolyte-Gated Graphene Field-Effect Transistors
- (2019) Rui Campos et al. ACS Sensors
- Nanomaterials-Based Colorimetric Immunoassays
- (2019) Lin Liu et al. Nanomaterials
- Role of beta-2-microglobulin as a biomarker in very preterm and extremely preterm infants with CNS inflammation
- (2019) Albert Batista Muñoz et al. PLoS One
- The MHC class I‐LILRB1 signalling axis as a promising target in cancer therapy
- (2019) Jinming Zhao et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Pretransplant serum beta‐2 microglobulin level is a potential novel prognostic marker of overall survival after allogeneic hematopoietic cell transplantation – a retrospective observational study
- (2019) Naonori Harada et al. TRANSPLANT INTERNATIONAL
- Correlation Coefficients
- (2018) Patrick Schober et al. ANESTHESIA AND ANALGESIA
- Endogenous markers for kidney function in children: a review
- (2018) Emil den Bakker et al. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
- Beta 2-Microglobulin and the Severity of Coronary Stenosis in Patients With Acute Coronary Syndrome
- (2018) Chenglong Zhang et al. Heart Lung and Circulation
- Ratiometric quantification of β2-microglobulin antigen in human serum based on elemental labeling strategy
- (2018) Gongwei Sun et al. TALANTA
- Comparative validation of a microcapsule-based immunoassay for the detection of proteins and nucleic acids
- (2018) Sujit Kumar Verma et al. PLoS One
- Serum kidney injury molecule 1 and β2-microglobulin perform as well as larger biomarker panels for prediction of rapid decline in renal function in type 2 diabetes
- (2018) Marco Colombo et al. DIABETOLOGIA
- Biomarkers of drug-induced kidney toxicity
- (2018) Benjamin R. Griffin et al. THERAPEUTIC DRUG MONITORING
- Selecting analytical biomarkers for diagnostic applications: a first principles approach
- (2017) Samantha A. Byrnes et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Preparation of an epitope-imprinted polymer with antibody-like selectivity for beta2-microglobulin and application in serum sample analysis with a facile method of on-line solid-phase extraction coupling with high performance liquid chromatography
- (2017) Fangfang Yang et al. JOURNAL OF CHROMATOGRAPHY A
- A dual-label time-resolved fluorescence immunoassay for the simultaneous determination of ferritin and β2 -microglobulin
- (2017) Zhi Liu et al. JOURNAL OF CLINICAL LABORATORY ANALYSIS
- Beta-2 microglobulin clearance in high-flux dialysis and convective dialysis modalities: a meta-analysis of published studies
- (2017) Maria-Eleni Roumelioti et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Neurosurgical aspects of dialysis-related spinal amyloidosis: Report of three cases and a review of the literature
- (2017) M. Dalolio et al. NEUROCHIRURGIE
- Computational design of cyclic peptides for the customized oriented immobilization of globular proteins
- (2017) Miguel A. Soler et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS
- (2017) Zu-yun Liu et al. Clinical Interventions in Aging
- Immunophysical analysis of corneal neovascularization: mechanistic insights and implications for pharmacotherapy
- (2017) Youness Azimzade et al. Scientific Reports
- “To Catch or Not to Catch”: Microcapsule-Based Sandwich Assay for Detection of Proteins and Nucleic Acids
- (2016) Sujit K. Verma et al. ADVANCED FUNCTIONAL MATERIALS
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- (2016) Lesley A. Inker et al. AMERICAN JOURNAL OF KIDNEY DISEASES
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- (2016) Satish Balasaheb Nimse et al. ANALYST
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- The Implication and Significance of Beta 2 Microglobulin: A Conservative Multifunctional Regulator
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- (2016) William J Polacheck et al. NATURE METHODS
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- (2016) Hironobu Naiki et al. PATHOLOGY INTERNATIONAL
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- (2015) Chloé Latour et al. HEPATOLOGY
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- (2015) Suhua Li et al. JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
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- (2015) Helen C. Looker et al. KIDNEY INTERNATIONAL
- Wild Type Beta-2 Microglobulin and DE Loop Mutants Display a Common Fibrillar Architecture
- (2015) Antonino Natalello et al. PLoS One
- Plasma Levels of Middle Molecules to Estimate Residual Kidney Function in Haemodialysis without Urine Collection
- (2015) Enric Vilar et al. PLoS One
- A Quantitative Relaxometric Version of the ELISA Test for the Measurement of Cell Surface Biomarkers
- (2014) Diego Alberti et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy
- (2014) Takeo Nomura et al. Anti-Cancer Agents in Medicinal Chemistry
- Beta-2 microglobulin-based equation for estimating glomerular filtration rates in Japanese children and adolescents
- (2014) Yohei Ikezumi et al. Clinical and Experimental Nephrology
- Clinical utility of serum beta-2-microglobulin as a predictor of diabetic complications in patients with type 2 diabetes without renal impairment
- (2014) M.K. Kim et al. DIABETES & METABOLISM
- Serum beta 2-microglobulin as a biomarker in inflammatory bowel disease
- (2014) Bülent Yılmaz WORLD JOURNAL OF GASTROENTEROLOGY
- Bio-barcode gel assay for microRNA
- (2014) Hyojin Lee et al. Nature Communications
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- (2013) Ming Li et al. ACS Nano
- Comparison of Serum Concentrations of -Trace Protein, 2-Microglobulin, Cystatin C, and Creatinine in the US Population
- (2013) S. P. Juraschek et al. Clinical Journal of the American Society of Nephrology
- Accumulation of advanced glycation end products and beta 2-microglobulin in fibrotic thickening of the peritoneum in long-term peritoneal dialysis patients
- (2013) Hirotaka Nakamoto et al. JOURNAL OF ARTIFICIAL ORGANS
- Urinary beta-2 microglobulin and alpha-1 microglobulin are useful screening markers for tenofovir-induced kidney tubulopathy in patients with HIV-1 infection: a diagnostic accuracy study
- (2013) Misao Takano et al. JOURNAL OF INFECTION AND CHEMOTHERAPY
- Three-Mode Electrochemical Sensing of Ultralow MicroRNA Levels
- (2013) Mahmoud Labib et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Probing the Unique Dehydration-Induced Structural Modifications in Cancer Cell DNA Using Surface Enhanced Raman Spectroscopy
- (2013) Sajanlal R. Panikkanvalappil et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Serum Levels of Beta2-Microglobulin and Free Light Chains of Immunoglobulins Are Associated with Systemic Disease Activity in Primary Sjögren’s Syndrome. Data at Enrollment in the Prospective ASSESS Cohort
- (2013) Jacques-Eric Gottenberg et al. PLoS One
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- (2012) Bhaskara V. Chikkaveeraiah et al. ACS Nano
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- (2012) Pakorn Preechaburana et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Biosensors based on nanomechanical systems
- (2012) Javier Tamayo et al. CHEMICAL SOCIETY REVIEWS
- Establishment of a normal reference value for serum β2 microglobulin in Japanese children: reevaluation of its clinical usefulness
- (2012) Yohei Ikezumi et al. Clinical and Experimental Nephrology
- Validating urinary measurement of beta-2-microglobulin with a Roche reagent kit designed for serum measurements
- (2012) Pak Cheung R. Chan et al. CLINICAL BIOCHEMISTRY
- Plasmonic ELISA for the ultrasensitive detection of disease biomarkers with the naked eye
- (2012) Roberto de la Rica et al. Nature Nanotechnology
- Hereditary Systemic Amyloidosis Due to Asp76Asn Variant β2-Microglobulin
- (2012) Sophie Valleix et al. NEW ENGLAND JOURNAL OF MEDICINE
- Leveraging on nanomechanical sensors to single out active small ligands for β2-microglobulin
- (2012) Giulio Oliviero et al. SENSORS AND ACTUATORS B-CHEMICAL
- Sensitivity Improved Surface Plasmon Resonance Biosensor for Cancer Biomarker Detection Based on Plasmonic Enhancement
- (2011) Wing-Cheung Law et al. ACS Nano
- High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number
- (2011) Benjamin J. Hindson et al. ANALYTICAL CHEMISTRY
- Beta-2 microglobulin as an immunological marker to assess the progression of human immunodeficiency virus infected patients on highly active antiretroviral therapy
- (2011) Pachiappan Chitra et al. CLINICA CHIMICA ACTA
- Comparative advantages of mechanical biosensors
- (2011) J.L. Arlett et al. Nature Nanotechnology
- Baseline Values of Candidate Urine Acute Kidney Injury Biomarkers Vary by Gestational Age in Premature Infants
- (2011) David J Askenazi et al. PEDIATRIC RESEARCH
- Beta2-Microglobulin Can Be a Disease Activity Marker in Systemic Lupus Erythematosus
- (2010) Hyoun-Ah Kim et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Attomolar Detection of a Cancer Biomarker Protein in Serum by Surface Plasmon Resonance Using Superparamagnetic Particle Labels
- (2010) Sadagopan Krishnan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Beta-2-microglobulin is an independent predictor of progression in asymptomatic multiple myeloma
- (2010) Davide Rossi et al. CANCER
- Urinary β-2-microglobulin as an alternative marker for fetal inflammatory response and development of bronchopulmonary dysplasia in premature infants
- (2010) Y Shima et al. Journal of Perinatology
- Discovery and Verification of Osteopontin and Beta-2-microglobulin as Promising Markers for Staging Human African Trypanosomiasis
- (2010) Natalia Tiberti et al. MOLECULAR & CELLULAR PROTEOMICS
- Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations
- (2010) David M Rissin et al. NATURE BIOTECHNOLOGY
- What are biomarkers?
- (2010) Kyle Strimbu et al. Current Opinion in HIV and AIDS
- β2-microglobulin: from physiology to amyloidosis
- (2009) Niels H. H. Heegaard AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
- Quantitative time-resolved measurement of membrane protein–ligand interactions using microcantilever array sensors
- (2009) Thomas Braun et al. Nature Nanotechnology
- β2-Microglobulin for Risk Stratification of Total Mortality in the Elderly PopulationComparison With Cystatin C and C-Reactive Protein
- (2008) Shoji Shinkai ARCHIVES OF INTERNAL MEDICINE
- Physicochemical and biological assays for quality control of biopharmaceuticals: Interferon alfa-2 case study
- (2008) Marta M.C.G. Silva et al. BIOLOGICALS
- β2-Microglobulin: emerging as a promising cancer therapeutic target
- (2008) Chunmeng Shi et al. DRUG DISCOVERY TODAY
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