4.7 Review

Cancer Targeting and Diagnosis: Recent Trends with Carbon Nanotubes

Journal

NANOMATERIALS
Volume 12, Issue 13, Pages -

Publisher

MDPI
DOI: 10.3390/nano12132283

Keywords

carbon nanotubes; electrochemical sensing; photoacoustic imaging; photothermal therapy; photodymanic therapy; gene therapy; immunotherapy

Funding

  1. Natural Science Foundation of Shandong Province [ZR2020QC061]
  2. Liaocheng University [318051901]
  3. Double-Hundred Talent Plan of Shandong Province, China

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This review discusses the recent advancements of carbon nanotubes (CNTs) in cancer diagnosis and therapy, including various sensing strategies and treatment techniques. It also emphasizes the importance of ensuring the safety of CNTs for biomedical applications.
Cancer belongs to a category of disorders characterized by uncontrolled cell development with the potential to invade other bodily organs, resulting in an estimated 10 million deaths globally in 2020. With advancements in nanotechnology-based systems, biomedical applications of nanomaterials are attracting increasing interest as prospective vehicles for targeted cancer therapy and enhancing treatment results. In this context, carbon nanotubes (CNTs) have recently garnered a great deal of interest in the field of cancer diagnosis and treatment due to various factors such as biocompatibility, thermodynamic properties, and varied functionalization. In the present review, we will discuss recent advancements regarding CNT contributions to cancer diagnosis and therapy. Various sensing strategies like electrochemical, colorimetric, plasmonic, and immunosensing are discussed in detail. In the next section, therapy techniques like photothermal therapy, photodynamic therapy, drug targeting, gene therapy, and immunotherapy are also explained in-depth. The toxicological aspect of CNTs for biomedical application will also be discussed in order to ensure the safe real-life and clinical use of CNTs.

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