Leishmania guyanensis suppressed inducible nitric oxide synthase provoked by its viral endosymbiont

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Analyses of Leishmania-LRV Co-Phylogenetic Patterns and Evolutionary Variability of Viral Proteins

(2021) Alexei Y. Kostygov et al.   Viruses-Basel

Leishmania Viannia guyanensis, LRV1 virus and extracellular vesicles: a dangerous trio influencing the faith of immune response during muco-cutaneous leishmaniasis

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IL-17 Affects the Progression, Metastasis, and Recurrence of Laryngeal Cancer via the Inhibition of Apoptosis through Activation of the PI3K/AKT/FAS/FASL Pathways

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Exploitation of the Leishmania exosomal pathway by Leishmania RNA virus 1

(2019) Vanessa Diniz Atayde et al.   Nature Microbiology

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Global status of synchronizing Leishmania RNA virus in Leishmania parasites: A systematic review with meta‐analysis

(2019) Reza Saberi et al.   Transboundary and Emerging Diseases

The role of interleukin-17 in tumor development and progression

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Gut Microbes Egested during Bites of Infected Sand Flies Augment Severity of Leishmaniasis via Inflammasome-Derived IL-1β

(2018) Ranadhir Dey et al.   Cell Host & Microbe

Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes

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Leishmania donovani inhibits inflammasome-dependent macrophage activation by exploiting the negative regulatory proteins A20 and UCP2

(2017) Anand Kumar Gupta et al.   FASEB JOURNAL

How to master the host immune system? Leishmania parasites have the solutions!

(2017) Matteo Rossi et al.   INTERNATIONAL IMMUNOLOGY

Antiviral screening identifies adenosine analogs targeting the endogenous dsRNALeishmaniaRNA virus 1 (LRV1) pathogenicity factor

(2017) F. Matthew Kuhlmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis

(2017) Matteo Rossi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection and molecular identification of leishmania RNA virus (LRV) in Iranian Leishmania species

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Activation of toll-like receptor signaling pathways leading to nitric oxide-mediated antiviral responses

(2016) Mohamed Sarjoon Abdul-Cader et al.   ARCHIVES OF VIROLOGY

Mammalian Innate Immune Response to a Leishmania -Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence

(2016) Remzi Onur Eren et al.   Cell Host & Microbe

Toll-like receptor 2 (TLR2) plays a role in controlling cutaneous leishmaniasis in vivo, but does not require activation by parasite lipophosphoglycan

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Leishmaniavirus-Dependent Metastatic Leishmaniasis Is Prevented by Blocking IL-17A

(2016) Mary-Anne Hartley et al.   PLoS Pathogens

Association of the Endobiont Double-Stranded RNA Virus LRV1 With Treatment Failure for Human Leishmaniasis Caused byLeishmania braziliensisin Peru and Bolivia

(2015) Vanessa Adaui et al.   JOURNAL OF INFECTIOUS DISEASES

Presence ofLeishmaniaRNA Virus 1 inLeishmania guyanensisIncreases the Risk of First-Line Treatment Failure and Symptomatic Relapse

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IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

(2015) Seth B. Coffelt et al.   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Nitric oxide synthase in innate and adaptive immunity: an update

(2015) Christian Bogdan   TRENDS IN IMMUNOLOGY

Induction, Propagation, and Activity of Host Nitric Oxide: Lessons from Leishmania Infection

(2015) Romain Olekhnovitch et al.   TRENDS IN PARASITOLOGY

Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex

(2015) Sebastian Wienerroither et al.   Cell Reports

Further Evidence of an Association between the Presence of Leishmania RNA Virus 1 and the Mucosal Manifestations in Tegumentary Leishmaniasis Patients

(2015) Lilian Motta Cantanhêde et al.   PLoS Neglected Tropical Diseases

Nitric oxide in cancer metastasis

(2014) Huiwen Cheng et al.   CANCER LETTERS

Severity of tegumentary leishmaniasis is not exclusively associated with Leishmania RNA virus 1 infection in Brazil

(2014) Luiza de Oliveira Ramos Pereira et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

(2014) Lieselotte Vande Walle et al.   NATURE

MyD88 and TLR9 Dependent Immune Responses Mediate Resistance to Leishmania guyanensis Infections, Irrespective of Leishmania RNA Virus Burden

(2014) Annette Ives et al.   PLoS One

The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis

(2014) Mary-Anne Hartley et al.   TRENDS IN PARASITOLOGY

Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling

(2013) Nataša Obermajer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A20 in inflammation and autoimmunity

(2013) Leen Catrysse et al.   TRENDS IN IMMUNOLOGY

Detection of Leishmania RNA Virus in Leishmania Parasites

(2013) Haroun Zangger et al.   PLoS Neglected Tropical Diseases

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

Leishmania donovani Exploits Host Deubiquitinating Enzyme A20, a Negative Regulator of TLR Signaling, To Subvert Host Immune Response

(2012) S. Srivastav et al.   JOURNAL OF IMMUNOLOGY

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

Compartmentalized Control of Skin Immunity by Resident Commensals

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Glycoconjugates in New World species of Leishmania: Polymorphisms in lipophosphoglycan and glycoinositolphospholipids and interaction with hosts

(2011) Rafael Ramiro de Assis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nitric Oxide Modulates TGF- -Directive Signals To Suppress Foxp3+ Regulatory T Cell Differentiation and Potentiate Th1 Development

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Leishmaniasis: complexity at the host–pathogen interface

(2011) Paul Kaye et al.   NATURE REVIEWS MICROBIOLOGY

Regulation of type 17 helper T-cell function by nitric oxide during inflammation

(2011) W. Niedbala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cap-snatching mechanism in yeast L-A double-stranded RNA virus

(2011) T. Fujimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leishmania RNA Virus Controls the Severity of Mucocutaneous Leishmaniasis

(2011) A. Ives et al.   SCIENCE

Nonconventional Initiation Complex Assembly by STAT and NF-κB Transcription Factors Regulates Nitric Oxide Synthase Expression

(2010) Matthias Farlik et al.   IMMUNITY

Regulation of the expression of inducible nitric oxide synthase

(2010) Andrea Pautz et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

A Dynamic Map of Antigen Recognition by CD4 T Cells at the Site of Leishmania major Infection

(2009) Orchidée Filipe-Santos et al.   Cell Host & Microbe

Distinct Roles for MyD88 and Toll-Like Receptor 2 during Leishmania braziliensis Infection in Mice

(2009) D. A. Vargas-Inchaustegui et al.   INFECTION AND IMMUNITY

IFN-  Impairs Superoxide-Dependent Parasite Killing in Human Macrophages: Evidence for a Deleterious Role of SOD1 in Cutaneous Leishmaniasis

(2009) R. Khouri et al.   JOURNAL OF IMMUNOLOGY

A20: Central Gatekeeper in Inflammation and Immunity

(2008) Beatrice Coornaert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY