Alphaherpesvirus US3 protein-mediated inhibition of the m6A mRNA methyltransferase complex

The m6A reader YTHDC2 is essential for escape from KSHV SOX-induced RNA decay

(2022) Daniel Macveigh-Fierro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA m 6 A methylation regulates virus–host interaction and EBNA2 expression during Epstein–Barr virus infection

(2021) Xiang Zheng et al.   Immunity Inflammation and Disease

Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine

(2021) Michael J. McFadden et al.   Cell Reports

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

(2021) Eliza Yankova et al.   NATURE

Pseudorabies virus inhibits type I and type III interferon-induced signaling via proteasomal degradation of Janus kinases

(2021) Yue Yin et al.   JOURNAL OF VIROLOGY

Widespread remodeling of the m6A RNA-modification landscape by a viral regulator of RNA processing and export

(2021) Kalanghad Puthankalam Srinivas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus

(2021) Miaoge Xue et al.   PLoS Pathogens

Pseudorabies virus infection of epithelial cells leads to persistent but aberrant activation of the NF-κB pathway, inhibiting hallmark NF-κB-induced pro-inflammatory gene expression

(2020) Nicolás Romero et al.   JOURNAL OF VIROLOGY

N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I

(2020) Mijia Lu et al.   Nature Microbiology

N6-Methyladenosine Modification of Hepatitis B and C Viral RNAs Attenuates Host Innate Immunity via RIG-I Signaling

(2020) Geon-Woo Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome

(2020) Yujiao Tang et al.   NUCLEIC ACIDS RESEARCH

CRISPR/Cas9-constructed pseudorabies virus mutants reveal the importance of UL13 in alphaherpesvirus escape from genome silencing

(2020) Jolien Van Cleemput et al.   JOURNAL OF VIROLOGY

EBV epitranscriptome reprogramming by METTL14 is critical for viral-associated tumorigenesis

(2019) Fengchao Lang et al.   PLoS Pathogens

Regulation of Viral Infection by the RNA Modification N6-methyladenosine

(2019) Graham D. Williams et al.   Annual Review of Virology

Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway

(2019) Wen Peng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi’s sarcoma-associated herpesvirus

(2019) Belinda Baquero-Perez et al.   eLife

Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection

(2019) Nandan S. Gokhale et al.   MOLECULAR CELL

Zc3h13 Regulates Nuclear RNA m 6 A Methylation and Mouse Embryonic Stem Cell Self-Renewal

(2018) Jing Wen et al.   MOLECULAR CELL

SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function

(2018) Yuzhang Du et al.   NUCLEIC ACIDS RESEARCH

N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection

(2018) Charles R. Hesser et al.   PLoS Pathogens

Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication

(2018) Kevin Tsai et al.   PLoS Pathogens

VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

(2018) Yanan Yue et al.   Cell Discovery

RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β

(2018) Rosa M. Rubio et al.   GENES & DEVELOPMENT

m6A modification controls the innate immune response to infection by targeting type I interferons

(2018) Roni Winkler et al.   NATURE IMMUNOLOGY

m 6 A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover

(2017) Shengdong Ke et al.   GENES & DEVELOPMENT

The Pseudorabies Virus Glycoprotein gE/gI Complex Suppresses Type I Interferon Production by Plasmacytoid Dendritic Cells

(2017) Jochen A. S. Lamote et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N 6 -Adenosine Methylation To Promote Lytic Replication

(2017) Fengchun Ye et al.   JOURNAL OF VIROLOGY

Viral and cellular N6-methyladenosine and N6,2′-O-dimethyladenosine epitranscriptomes in the KSHV life cycle

(2017) Brandon Tan et al.   Nature Microbiology

Posttranscriptional m 6 A Editing of HIV-1 mRNAs Enhances Viral Gene Expression

(2016) Edward M. Kennedy et al.   Cell Host & Microbe

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

(2016) Ping Wang et al.   MOLECULAR CELL

Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2016) Xiang Wang et al.   NATURE

N6-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression

(2016) Nagaraja Tirumuru et al.   eLife

Structural insights into the molecular mechanism of the m6A writer complex

(2016) Paweł Śledź et al.   eLife

Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells

(2016) Gianluigi Lichinchi et al.   Nature Microbiology

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

(2014) Xiao-Li Ping et al.   CELL RESEARCH

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

(2014) Yang Wang et al.   NATURE CELL BIOLOGY

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Keep it in the subfamily: the conserved alphaherpesvirus US3 protein kinase

(2010) M. J. Deruelle et al.   JOURNAL OF GENERAL VIROLOGY

Whole-genome analysis of pseudorabies virus gene expression by real-time quantitative RT-PCR assay

(2009) Dóra Tombácz et al.   BMC GENOMICS

Two Viral Kinases are Required for Sustained Long Distance Axon Transport of a Neuroinvasive Herpesvirus

(2008) Kelly E. Coller et al.   TRAFFIC