Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus

N6-methyladenosine modification of HIV-1 RNA suppresses type-I interferon induction in differentiated monocytic cells and primary macrophages

(2021) Shuliang Chen et al.   PLoS Pathogens

METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection

(2021) Na Li et al.   Cell Reports

Live-Attenuated Respiratory Syncytial Virus Vaccine With M2-2 Deletion and With Small Hydrophobic Noncoding Region Is Highly Immunogenic in Children

(2020) Elizabeth J McFarland et al.   JOURNAL OF INFECTIOUS DISEASES

N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I

(2020) Mijia Lu et al.   Nature Microbiology

m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development

(2020) Yimeng Gao et al.   IMMUNITY

N6-Methyladenosine Modification of Hepatitis B and C Viral RNAs Attenuates Host Innate Immunity via RIG-I Signaling

(2020) Geon-Woo Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic and epitranscriptomic regulation of viral replication

(2020) Kevin Tsai et al.   NATURE REVIEWS MICROBIOLOGY

Pulmonary function analysis in cotton rats after respiratory syncytial virus infection

(2020) Margaret E. Martinez et al.   PLoS One

RNA Modifications Modulate Activation of Innate Toll-Like Receptors

(2019) Isabel Freund et al.   Genes

Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity

(2019) Cristhian Cadena et al.   CELL

Respiratory Syncytial Virus Vaccines

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Immunological Lessons from Respiratory Syncytial Virus Vaccine Development

(2019) Tracy J. Ruckwardt et al.   IMMUNITY

N6-Methyladenosine Modification Controls Circular RNA Immunity

(2019) Y. Grace Chen et al.   MOLECULAR CELL

Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

(2019) Miaoge Xue et al.   Nature Communications

Regulation of cGAS- and RLR-mediated immunity to nucleic acids

(2019) Andrea Ablasser et al.   NATURE IMMUNOLOGY

RIG-I and Other RNA Sensors in Antiviral Immunity

(2018) Kwan T. Chow et al.   Annual Review of Immunology

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

(2018) Ying Yang et al.   CELL RESEARCH

N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection

(2018) Charles R. Hesser et al.   PLoS Pathogens

Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development

(2018) Mateusz Mendel et al.   MOLECULAR CELL

RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β

(2018) Rosa M. Rubio et al.   GENES & DEVELOPMENT

m6A modification controls the innate immune response to infection by targeting type I interferons

(2018) Roni Winkler et al.   NATURE IMMUNOLOGY

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

(2017) Ting Shi et al.   LANCET

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

(2017) Ly P Vu et al.   NATURE MEDICINE

Animal models of respiratory syncytial virus infection

(2017) Geraldine Taylor   VACCINE

Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses

(2017) Srirupa Chatterjee et al.   Nature Microbiology

Viral and cellular N6-methyladenosine and N6,2′-O-dimethyladenosine epitranscriptomes in the KSHV life cycle

(2017) Brandon Tan et al.   Nature Microbiology

N6 -Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection

(2016) Nandan S. Gokhale et al.   Cell Host & Microbe

RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling

(2016) Ann Fiegen Durbin et al.   mBio

A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

(2016) Christopher C. Stobart et al.   Nature Communications

Determinants of early life immune responses to RSV infection

(2016) Tracy J Ruckwardt et al.   Current Opinion in Virology

RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

(2016) Saurabh Chattopadhyay et al.   Protein & Cell

Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells

(2016) Gianluigi Lichinchi et al.   Nature Microbiology

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

(2014) Xiao-Li Ping et al.   CELL RESEARCH

Incoming RNA Virus Nucleocapsids Containing a 5′-Triphosphorylated Genome Activate RIG-I and Antiviral Signaling

(2013) Michaela Weber et al.   Cell Host & Microbe

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Respiratory Syncytial Virus Modified by Deletions of the NS2 Gene and Amino Acid S1313 of the L Polymerase Protein Is a Temperature-Sensitive, Live-Attenuated Vaccine Candidate That Is Phenotypically Stable at Physiological Temperature

(2012) C. Luongo et al.   JOURNAL OF VIROLOGY

The Human Respiratory Syncytial Virus Nonstructural Protein 1 Regulates Type I and Type II Interferon Pathways

(2012) Marcus L. Hastie et al.   MOLECULAR & CELLULAR PROTEOMICS

Erratum: Corrigendum: N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2012) Guifang Jia et al.   Nature Chemical Biology

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

Human Respiratory Syncytial Virus Nonstructural Protein NS2 Antagonizes the Activation of Beta Interferon Transcription by Interacting with RIG-I

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Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells

(2008) P. A. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA