P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles

Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients

(2022) A. Joseph Bloom et al.   Molecular Neurodegeneration

Four subgroups based on tau levels in Alzheimer’s disease observed in two independent cohorts

(2021) Flora H. Duits et al.   Alzheimers Research & Therapy

Onset of Preclinical Alzheimer Disease in Monozygotic Twins

(2021) Elles Konijnenberg et al.   ANNALS OF NEUROLOGY

Role of SNAREs in Neurodegenerative Diseases

(2021) Azzurra Margiotta   Cells

CSF Synaptic Biomarkers in the Preclinical Stage of Alzheimer Disease and Their Association With MRI and PET: A Cross-sectional Study

(2021) Marta Milà-Alomà et al.   NEUROLOGY

CSF p-tau increase in response to Aβ-type and Danish-type cerebral amyloidosis and in the absence of neurofibrillary tangles

(2021) Stephan A. Kaeser et al.   ACTA NEUROPATHOLOGICA

The β-secretase BACE1 in Alzheimer’s disease

(2020) Harald Hampel et al.   BIOLOGICAL PSYCHIATRY

Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum

(2020) Marta Milà‐Alomà et al.   Alzheimers & Dementia

Targeting tau: Clinical trials and novel therapeutic approaches

(2020) Lawren VandeVrede et al.   NEUROSCIENCE LETTERS

Cerebrospinal fluid A beta 1–40 peptides increase in Alzheimer’s disease and are highly correlated with phospho-tau in control individuals

(2020) Sylvain Lehmann et al.   Alzheimers Research & Therapy

An examination of a novel multipanel of CSF biomarkers in the Alzheimer's disease clinical and pathological continuum

(2020) Carol Van Hulle et al.   Alzheimers & Dementia

Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer’s disease

(2020) Joana B Pereira et al.   BRAIN

Changes in synaptic proteins precede neurodegeneration markers in preclinical Alzheimer’s disease cerebrospinal fluid

(2019) Alberto Lleó et al.   MOLECULAR & CELLULAR PROTEOMICS

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

(2019) Brian W. Kunkle et al.   NATURE GENETICS

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology

(2019) Claire Bridel et al.   JAMA Neurology

Role of Neurofilament Light Chain as a Potential Biomarker for Alzheimer's Disease: A Correlative Meta-Analysis

(2019) Mei Jin et al.   Frontiers in Aging Neuroscience

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Bi-directional Association of Cerebrospinal Fluid Immune Markers with Stage of Alzheimer’s Disease Pathogenesis

(2018) Pierre-François Meyer et al.   JOURNAL OF ALZHEIMERS DISEASE

Amsterdam Dementia Cohort: Performing Research to Optimize Care

(2018) Wiesje M. van der Flier et al.   JOURNAL OF ALZHEIMERS DISEASE

Pre-amyloid stage of Alzheimer's disease in cognitively normal individuals

(2018) Betty M. Tijms et al.   Annals of Clinical and Translational Neurology

BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer’s Disease Markers in Elderly Healthy Participants

(2017) Maarten Timmers et al.   JOURNAL OF ALZHEIMERS DISEASE

Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease

(2016) Niklas Mattsson et al.   EMBO Molecular Medicine

Synaptic degeneration and neurogranin in the pathophysiology of Alzheimer’s disease

(2016) Simone Lista et al.   Expert Review of Neurotherapeutics

CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

(2016) Bob Olsson et al.   LANCET NEUROLOGY

Synaptic degeneration and neurogranin in the pathophysiology of Alzheimer’s disease

(2016) Simone Lista et al.   Expert Review of Neurotherapeutics

Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease

(2015) Hlin Kvartsberg et al.   Alzheimers & Dementia

Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer’s disease

(2015) Erik Portelius et al.   BRAIN

Alzheimer’s disease cerebrospinal fluid biomarker in cognitively normal subjects

(2015) Jon B. Toledo et al.   BRAIN

Discriminatory and predictive capabilities of enzyme-linked immunosorbent assay and multiplex platforms in a longitudinal Alzheimer’s disease study

(2012) Wesley Jongbloed et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Elevated Cerebrospinal Fluid BACE1 Activity in Incipient Alzheimer Disease

(2008) Henrik Zetterberg et al.   ARCHIVES OF NEUROLOGY