Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer’s disease
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer’s disease
Authors
Keywords
-
Journal
BRAIN
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2020-10-24
DOI
10.1093/brain/awaa395
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Aβ deposition is associated with increases in soluble and phosphorylated tau that precede a positive Tau PET in Alzheimer’s disease
- (2020) Niklas Mattsson-Carlgren et al. Science Advances
- Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders
- (2020) Sebastian Palmqvist et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease
- (2019) Oliver Preische et al. NATURE MEDICINE
- Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease
- (2019) Suzanne E. Schindler et al. Alzheimers & Dementia
- Neurofilament light chain as a biomarker in neurological disorders
- (2019) Lorenzo Gaetani et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Neuromodulatory action of picomolar extracellular Aβ42 oligomers on pre- and postsynaptic mechanisms underlying synaptic function and memory
- (2019) Walter Gulisano et al. JOURNAL OF NEUROSCIENCE
- A Unifying Hypothesis for Alzheimer’s Disease: From Plaques to Neurodegeneration
- (2019) Frances A. Edwards TRENDS IN NEUROSCIENCES
- Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease
- (2019) Niklas Mattsson et al. JAMA Neurology
- Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort
- (2019) Caitlin S. Latimer et al. Acta Neuropathologica Communications
- Amyloid-β and Synaptic Vesicle Dynamics: A Cacophonic Orchestra
- (2019) Francesca Fagiani et al. JOURNAL OF ALZHEIMERS DISEASE
- Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer's disease
- (2018) Courtney L. Sutphen et al. Alzheimers & Dementia
- NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
- (2018) Clifford R. Jack et al. Alzheimers & Dementia
- Tau Kinetics in Neurons and the Human Central Nervous System
- (2018) Chihiro Sato et al. NEURON
- The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease
- (2018) Hlin Kvartsberg et al. ACTA NEUROPATHOLOGICA
- Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology
- (2018) Åsa Sandelius et al. Alzheimers & Dementia
- Correlation of In Vivo [18F]Flortaucipir With Postmortem Alzheimer Disease Tau Pathology
- (2018) Ruben Smith et al. JAMA Neurology
- Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers
- (2017) Kaitlin B. Casaletto et al. NEUROLOGY
- Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity
- (2017) Sebastian Palmqvist et al. Nature Communications
- Cerebrospinal fluid analysis detects cerebral amyloid-β accumulation earlier than positron emission tomography
- (2016) Sebastian Palmqvist et al. BRAIN
- Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease
- (2016) Niklas Mattsson et al. EMBO Molecular Medicine
- Modeling Strategies for Quantification of In Vivo 18 F-AV-1451 Binding in Patients with Tau Pathology
- (2016) Andreas Hahn et al. JOURNAL OF NUCLEAR MEDICINE
- Complement and microglia mediate early synapse loss in Alzheimer mouse models
- (2016) S. Hong et al. SCIENCE
- Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression
- (2016) Henrik Zetterberg et al. JAMA Neurology
- Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer’s disease
- (2015) Erik Portelius et al. BRAIN
- Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression
- (2015) Willem Huijbers et al. BRAIN
- Cascading network failure across the Alzheimer’s disease spectrum
- (2015) David T. Jones et al. BRAIN
- Measurement of Longitudinal -Amyloid Change with 18F-Florbetapir PET and Standardized Uptake Value Ratios
- (2015) S. M. Landau et al. JOURNAL OF NUCLEAR MEDICINE
- Neurogranin Levels in Cerebrospinal Fluid
- (2015) Henrik Zetterberg et al. JAMA Neurology
- Primary age-related tauopathy (PART): a common pathology associated with human aging
- (2014) John F. Crary et al. ACTA NEUROPATHOLOGICA
- Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50–89 years: a cross-sectional study
- (2014) Clifford R Jack et al. LANCET NEUROLOGY
- SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease
- (2014) Ann Brinkmalm et al. Molecular Neurodegeneration
- Neural compensation in older people with brain amyloid-β deposition
- (2014) Jeremy A Elman et al. NATURE NEUROSCIENCE
- The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease
- (2014) Tara L. Spires-Jones et al. NEURON
- Resting State Functional Connectivity in Preclinical Alzheimer’s Disease
- (2013) Yvette I. Sheline et al. BIOLOGICAL PSYCHIATRY
- Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin
- (2013) Hans Zempel et al. EMBO JOURNAL
- A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric A , and Frank Neuronal Loss
- (2013) R. M. Cohen et al. JOURNAL OF NEUROSCIENCE
- Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
- (2013) Clifford R Jack et al. LANCET NEUROLOGY
- Brain -amyloid load approaches a plateau
- (2013) C. R. Jack et al. NEUROLOGY
- Structural foundations of resting-state and task-based functional connectivity in the human brain
- (2013) A. M. Hermundstad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex
- (2013) A. L. Allegra Mascaro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and Functional Brain Networks: From Connections to Cognition
- (2013) H.-J. Park et al. SCIENCE
- The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System
- (2012) Hwan-Ching Tai et al. AMERICAN JOURNAL OF PATHOLOGY
- Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
- (2012) Peter T. Nelson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease
- (2012) Steven E. Arnold et al. NEUROBIOLOGY OF AGING
- Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer’s disease
- (2011) Pamela E. Potter et al. ACTA NEUROPATHOLOGICA
- Functional network disruption in the degenerative dementias
- (2011) Michela Pievani et al. LANCET NEUROLOGY
- In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks
- (2010) Steffen Burgold et al. ACTA NEUROPATHOLOGICA
- Amyloid Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation
- (2010) H.-Y. Wu et al. JOURNAL OF NEUROSCIENCE
- A Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
- (2010) H. Zempel et al. JOURNAL OF NEUROSCIENCE
- Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
- (2010) Jorge J Palop et al. NATURE NEUROSCIENCE
- Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease
- (2010) Ahmadul Kadir et al. NEUROBIOLOGY OF AGING
- Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice
- (2010) Anete Rozkalne et al. NEUROBIOLOGY OF DISEASE
- Toward discovery science of human brain function
- (2010) B. B. Biswal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nicotinic Receptors, Amyloid-β, and Synaptic Failure in Alzheimer’s Disease
- (2009) Sofia Jürgensen et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
- (2009) Clifford R Jack et al. LANCET NEUROLOGY
- Oligomeric amyloid associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
- (2009) R. M. Koffie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Predicting human resting-state functional connectivity from structural connectivity
- (2009) C. J. Honey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tau pathophysiology in neurodegeneration: a tangled issue
- (2009) Tara L. Spires-Jones et al. TRENDS IN NEUROSCIENCES
- Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
- (2008) Milos D. Ikonomovic et al. BRAIN
- Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
- (2008) P. Hemachandra Reddy et al. TRENDS IN MOLECULAR MEDICINE
- Tract probability maps in stereotaxic spaces: Analyses of white matter anatomy and tract-specific quantification
- (2007) Kegang Hua et al. NEUROIMAGE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now