Neurotrophic factor-secreting cells restored endogenous hippocampal neurogenesis through the Wnt/β-catenin signaling pathway in AD model mice

Neural Stem Cells Secretome Increased Neurogenesis and Behavioral Performance and the Activation of Wnt/β-Catenin Signaling Pathway in Mouse Model of Alzheimer’s Disease

(2022) Farzaneh Hijroudi et al.   NEUROMOLECULAR MEDICINE

The GSK-3β/β-Catenin Signaling–Mediated Brain–Derived Neurotrophic Factor Pathway Is Involved in Aluminum-Induced Impairment of Hippocampal LTP In Vivo

(2021) Huifang Zhang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Application of neurotrophic factor-secreting cells (astrocyte - Like cells) in the in-vitro Alzheimer’s disease-like pathology on the human neuroblastoma cells

(2021) Fatemeh Jafari Jahed et al.   BRAIN RESEARCH BULLETIN

Current knowledge and challenges associated with targeted delivery of neurotrophic factors into the central nervous system: focus on available approaches

(2021) Gozal Bahlakeh et al.   Cell and Bioscience

The protective and therapeutic effects of vinpocetine, a PDE1 inhibitor, on oxidative stress and learning and memory impairment induced by an intracerebroventricular (ICV) injection of amyloid beta (aβ) peptide

(2020) Meysam Shekarian et al.   BEHAVIOURAL BRAIN RESEARCH

Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

(2020) Przemysław Duda et al.   Cells

Therapeutic potential of neurogenesis and melatonin regulation in Alzheimer's disease

(2020) Mazel Mihardja et al.   ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

The search for Alzheimer disease therapeutics — same targets, better trials?

(2020) Michael S. Rafii et al.   Nature Reviews Neurology

Unraveling the therapeutic effects of mesenchymal stem cells in asthma

(2020) Fatemeh Mirershadi et al.   Stem Cell Research & Therapy

Innovative Therapy for Alzheimer’s Disease-With Focus on Biodelivery of NGF

(2019) Sumonto Mitra et al.   Frontiers in Neuroscience

Inflammasomes in neuroinflammatory and neurodegenerative diseases

(2019) Sofie Voet et al.   EMBO Molecular Medicine

Burden of Neurodegenerative Diseases in the Eastern Mediterranean Region, 1990‐2016: Findings from the Global Burden of Disease 2016 Study

(2019) Seyed‐Mohammad Fereshtehnejad et al.   EUROPEAN JOURNAL OF NEUROLOGY

Quercetin promotes learning and memory performance concomitantly with neural stem/progenitor cell proliferation and neurogenesis in the adult rat dentate gyrus

(2019) Mohammad Karimipour et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Ageing as a risk factor for neurodegenerative disease

(2019) Yujun Hou et al.   Nature Reviews Neurology

Altered Insulin Signaling in Alzheimer’s Disease Brain – Special Emphasis on PI3K-Akt Pathway

(2019) Sami Gabbouj et al.   Frontiers in Neuroscience

Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer’s disease

(2019) Lin Jia et al.   Molecular Brain

Exercise-Mediated Neurogenesis in the Hippocampus via BDNF

(2018) Patrick Z. Liu et al.   Frontiers in Neuroscience

Amyloid-β1-42 dynamically regulates the migration of neural stem/progenitor cells via MAPK-ERK pathway

(2018) Zhu Wang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease

(2017) Na Jin et al.   EXPERIMENTAL NEUROLOGY

Investigation of thymol effect on learning and memory impairment induced by intrahippocampal injection of amyloid beta peptide in high fat diet- fed rats

(2017) Masoumeh Asadbegi et al.   METABOLIC BRAIN DISEASE

Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy

(2017) Simone Pinton et al.   Neural Regeneration Research

Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer’s Disease

(2016) Florence Guillot et al.   JOURNAL OF ALZHEIMERS DISEASE

Inhibition of Glycogen Synthase Kinase-3: An Emerging Target in the Treatment of Traumatic Brain Injury

(2016) Seong S. Shim et al.   JOURNAL OF NEUROTRAUMA

Regulation of Neurogenesis by Neurotrophins during Adulthood: Expected and Unexpected Roles

(2016) Marçal Vilar et al.   Frontiers in Neuroscience

Crosstalk Between MAPK/ERK and PI3K/AKT Signal Pathways During Brain Ischemia/Reperfusion

(2015) Jing Zhou et al.   ASN Neuro

Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Neuronal Differentiation by Enhancing the Wnt Signaling Pathway in an Alzheimer's Disease Model

(2015) Se Hee Oh et al.   CELL TRANSPLANTATION

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Roles of Wnt Signaling in the Neurogenic Niche of the Adult Mouse Ventricular–Subventricular Zone

(2015) Yuki Hirota et al.   NEUROCHEMICAL RESEARCH

Selective activation of α7 nicotinic acetylcholine receptor by PHA-543613 improves Aβ25–35-mediated cognitive deficits in mice

(2015) S. Sadigh-Eteghad et al.   NEUROSCIENCE

Adult Neurogenesis in Neurodegenerative Diseases: Figure 1.

(2015) Beate Winner et al.   Cold Spring Harbor Perspectives in Biology

Neurogenesis in the Adult Hippocampus

(2015) Gerd Kempermann et al.   Cold Spring Harbor Perspectives in Biology

The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease

(2015) Josiane Budni et al.   Aging and Disease

Adipose tissue-derived mesenchymal stem cells cultured at high cell density express brain-derived neurotrophic factor and exert neuroprotective effects in a 6-hydroxydopamine rat model of Parkinson’s disease

(2014) Joon Beom Park et al.   Genes & Genomics

Wnt signaling in the nervous system and in Alzheimer's disease

(2014) N. C. Inestrosa et al.   Journal of Molecular Cell Biology

Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease

(2014) Yasuko Kitagishi et al.   Alzheimers Research & Therapy

Systemic treatment with adipose-derived mesenchymal stem cells ameliorates clinical and pathological features in the amyotrophic lateral sclerosis murine model

(2013) S. Marconi et al.   NEUROSCIENCE

Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments

(2013) Margaret K. King et al.   PHARMACOLOGY & THERAPEUTICS

Wnts in adult brain: from synaptic plasticity to cognitive deficiencies

(2013) Carolina A. Oliva et al.   Frontiers in Cellular Neuroscience

Signaling mechanisms regulating adult neural stem cells and neurogenesis

(2012) Roland Faigle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Receptor Tyrosine Kinases Activate Canonical WNT/β-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct β-Catenin Phosphorylation

(2012) Pavel Krejci et al.   PLoS One

In Vivo Clonal Analysis Reveals Self-Renewing and Multipotent Adult Neural Stem Cell Characteristics

(2011) Michael A. Bonaguidi et al.   CELL

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

Neurotrophic factors in Alzheimer’s disease: role of axonal transport

(2010) K. Schindowski et al.   GENES BRAIN AND BEHAVIOR

Neurogenesis and Alzheimer's disease: At the crossroads

(2009) Orly Lazarov et al.   EXPERIMENTAL NEUROLOGY

Therapeutic Effects of Human Mesenchymal Stem Cells on Traumatic Brain Injury in Rats: Secretion of Neurotrophic Factors and Inhibition of Apoptosis

(2009) Hwa-Jung Kim et al.   JOURNAL OF NEUROTRAUMA

Protective Effects of Neurotrophic Factor–Secreting Cells in a 6-OHDA Rat Model of Parkinson Disease

(2009) Ofer Sadan et al.   STEM CELLS AND DEVELOPMENT

Amyloid-β Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/β-Catenin Signaling

(2008) Margaret H. Magdesian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Migration of Neurotrophic Factors-Secreting Mesenchymal Stem Cells Toward a Quinolinic Acid Lesion as Viewed by Magnetic Resonance Imaging

(2008) Ofer Sadan et al.   STEM CELLS