Stress Granules Determine the Development of Obesity-Associated Pancreatic Cancer

Association of Obesity With Survival Outcomes in Patients With Cancer

(2021) Fausto Petrelli et al.   JAMA Network Open

Pancreatic Cancer

(2021) Wungki Park et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Stress granules inhibit fatty acid oxidation by modulating mitochondrial permeability

(2021) Triana Amen et al.   Cell Reports

Plasma Myokine Concentrations After Acute Exercise in Non-obese and Obese Sedentary Women

(2020) Léa Garneau et al.   Frontiers in Physiology

Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

(2020) Katherine Minjee Chung et al.   CELL

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

(2020) Peiguo Yang et al.   CELL

Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer

(2020) Maria Victoria Recouvreux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammation and Cancer: Triggers, Mechanisms, and Consequences

(2019) Florian R. Greten et al.   IMMUNITY

Autophagy role(s) in response to oncogenes and DNA replication stress

(2019) Riccardo Vanzo et al.   CELL DEATH AND DIFFERENTIATION

Obesity dysregulates fasting-induced changes in glucagon secretion

(2019) Jennifer H Stern et al.   JOURNAL OF ENDOCRINOLOGY

Brain-Behavior-Immune Interaction: Serum Cytokines and Growth Factors in Patients with Eating Disorders at Extremes of the Body Mass Index (BMI) Spectrum

(2019) Mariarita Caroleo et al.   Nutrients

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

(2018) Sebastian Markmiller et al.   CELL

The mTOR-S6 kinase pathway promotes stress granule assembly

(2018) Aristeidis P. Sfakianos et al.   CELL DEATH AND DIFFERENTIATION

IGF1 receptor signaling pathways

(2018) Fumihiko Hakuno et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Systematic Characterization of Stress-Induced RNA Granulation

(2018) Sim Namkoong et al.   MOLECULAR CELL

Plasminogen Activator Inhibitor-1 Level Correlates with Lipoprotein Subfractions in Obese Nondiabetic Subjects

(2018) Sándor Somodi et al.   International Journal of Endocrinology

Distinct mechanisms govern the phosphorylation of different SR protein splicing factors

(2018) Yunxin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules

(2017) Anthony Khong et al.   MOLECULAR CELL

Health Effects of Overweight and Obesity in 195 Countries over 25 Years

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules

(2016) Elda Grabocka et al.   CELL

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity

(2016) J. Incio et al.   CLINICAL CANCER RESEARCH

Trends in Obesity Among Adults in the United States, 2005 to 2014

(2016) Katherine M. Flegal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Trends in Obesity Prevalence Among Children and Adolescents in the United States, 1988-1994 Through 2013-2014

(2016) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy

(2016) J. Incio et al.   Cancer Discovery

Cytokine profiles in overweight and obese subjects and normal weight individuals matched for age and gender

(2016) Maryam Azizian et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells

(2015) A. Lo et al.   CANCER RESEARCH

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

(2015) Syam Prakash Somasekharan et al.   JOURNAL OF CELL BIOLOGY

The S6K protein family in health and disease

(2015) Mariana R. Tavares et al.   LIFE SCIENCES

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis

(2015) Bo Ri Seo et al.   Science Translational Medicine

The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly

(2015) Carmela Sidrauski et al.   eLife

Stress granules are dispensable for mRNA stabilization during cellular stress

(2014) Nadine Bley et al.   NUCLEIC ACIDS RESEARCH

Insulin Receptor Signaling in Normal and Insulin-Resistant States

(2014) J. Boucher et al.   Cold Spring Harbor Perspectives in Biology

Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells

(2013) Kathrin Thedieck et al.   CELL

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

(2013) Cosimo Commisso et al.   NATURE

Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer

(2012) Lauren J. Bayne et al.   CANCER CELL

SRPK2 Phosphorylates Tau and Mediates the Cognitive Defects in Alzheimer's Disease

(2012) Y. Hong et al.   JOURNAL OF NEUROSCIENCE

Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue

(2012) Noritaka Kawasaki et al.   Scientific Reports

Only C-Reactive Protein, but not TNF-α or IL6, Reflects the Improvement in Inflammation after Bariatric Surgery

(2011) Eva Pardina et al.   OBESITY SURGERY

Stress-specific composition, assembly and kinetics of stress granules in Saccharomyces cerevisiae

(2010) J. R. Buchan et al.   JOURNAL OF CELL SCIENCE

TDP-43 Is Directed to Stress Granules by Sorbitol, a Novel Physiological Osmotic and Oxidative Stressor

(2010) C. M. Dewey et al.   MOLECULAR AND CELLULAR BIOLOGY

Reversal of Obesity and Insulin Resistance by a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist in Diet-Induced Obese Mice

(2010) Min He et al.   PLoS One

Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways

(2009) A. J. Schetter et al.   CARCINOGENESIS

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

(2009) Ji Luo et al.   CELL

Interaction of Akt-phosphorylated SRPK2 with 14-3-3 Mediates Cell Cycle and Cell Death in Neurons

(2009) Sung-Wuk Jang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

Obesity potentiates the growth and dissemination of pancreatic cancer

(2009) Nicholas J. Zyromski et al.   SURGERY

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules

(2008) I. Goulet et al.   HUMAN MOLECULAR GENETICS

Hypoxic Inhibition of Nonsense-Mediated RNA Decay Regulates Gene Expression and the Integrated Stress Response

(2008) L. B. Gardner   MOLECULAR AND CELLULAR BIOLOGY

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

(2008) Kyoko Arimoto et al.   NATURE CELL BIOLOGY