Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer
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Title
Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer
Authors
Keywords
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Journal
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 217, Issue 9, Pages -
Publisher
Rockefeller University Press
Online
2020-06-08
DOI
10.1084/jem.20200388
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Note: Only part of the references are listed.- Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis
- (2019) Wei Lu et al. DEVELOPMENTAL CELL
- Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
- (2019) Yingyao Zhou et al. Nature Communications
- EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis
- (2019) Szu-Wei Lee et al. DEVELOPMENTAL CELL
- Translational reprogramming marks adaptation to asparagine restriction in cancer
- (2019) Gaurav Pathria et al. NATURE CELL BIOLOGY
- Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
- (2018) Dana M. Gwinn et al. CANCER CELL
- EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration
- (2018) Nicole M. Aiello et al. DEVELOPMENTAL CELL
- A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3
- (2018) Mylène Tajan et al. Cell Metabolism
- We're Not “DON” Yet: Optimal Dosing and Prodrug Delivery of6-Diazo-5-oxo-L-norleucine
- (2018) Kathryn M. Lemberg et al. MOLECULAR CANCER THERAPEUTICS
- Starvation and Pseudo-Starvation as Drivers of Cancer Metastasis through Translation Reprogramming
- (2018) Custodia García-Jiménez et al. Cell Metabolism
- Stratification of Pancreatic Ductal Adenocarcinomas Based on Tumor and Microenvironment Features
- (2018) Francesco Puleo et al. GASTROENTEROLOGY
- Metabolic reprogramming and epithelial-to-mesenchymal transition in cancer
- (2017) Marco Sciacovelli et al. FEBS Journal
- Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma
- (2017) Paola Falletta et al. GENES & DEVELOPMENT
- Glucose feeds the TCA cycle via circulating lactate
- (2017) Sheng Hui et al. NATURE
- Upholding a role for EMT in pancreatic cancer metastasis
- (2017) Nicole M. Aiello et al. NATURE
- The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
- (2017) Angela M. Krebs et al. NATURE CELL BIOLOGY
- Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
- (2017) Douglas E. Biancur et al. Nature Communications
- A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer
- (2017) Nicholas Villarino et al. Oncotarget
- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells
- (2016) Aaron M. Hosios et al. DEVELOPMENTAL CELL
- The integrated stress response
- (2016) Karolina Pakos‐Zebrucka et al. EMBO REPORTS
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation
- (2016) Min Pan et al. NATURE CELL BIOLOGY
- Autocrine epiregulin activates EGFR pathway for lung metastasis via EMT in salivary adenoid cystic carcinoma
- (2016) Shuli Liu et al. Oncotarget
- Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
- (2015) J. J. Kamphorst et al. CANCER RESEARCH
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma
- (2015) Richard A Moffitt et al. NATURE GENETICS
- Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma
- (2015) Boris Ratnikov et al. Oncotarget
- Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion
- (2014) Ji Zhang et al. MOLECULAR CELL
- Molecular signatures of mRNAs and miRNAs as prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas
- (2014) V. Sandhu et al. Molecular Oncology
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- Pharmacological brake-release of mRNA translation enhances cognitive memory
- (2013) Carmela Sidrauski et al. eLife
- Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer
- (2012) Lauren J. Bayne et al. CANCER CELL
- EMT and Dissemination Precede Pancreatic Tumor Formation
- (2012) Andrew D. Rhim et al. CELL
- Molecular markers associated with outcome and metastasis in human pancreatic cancer
- (2012) Anke Van den Broeck et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Selection of Metastatic Breast Cancer Cells Based on Adaptability of Their Metabolic State
- (2012) Balraj Singh et al. PLoS One
- In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines
- (2011) Z Adhim et al. BRITISH JOURNAL OF CANCER
- Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
- (2011) Eric A Collisson et al. NATURE MEDICINE
- The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
- (2010) Jiangbin Ye et al. EMBO JOURNAL
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Extracellular Signal-Regulated Kinase Signaling Pathway Regulates Breast Cancer Cell Migration by Maintaining slug Expression
- (2009) H. Chen et al. CANCER RESEARCH
- Glutamine Deprivation Induces Abortive S-Phase Rescued by Deoxyribonucleotides in K-Ras Transformed Fibroblasts
- (2009) Daniela Gaglio et al. PLoS One
- Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells
- (2009) Nawneet K. Kurrey et al. STEM CELLS
- MEK Signaling Is Required for Phosphorylation of eIF2α following Amino Acid Limitation of HepG2 Human Hepatoma Cells
- (2008) Michelle M. Thiaville et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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