Mechanistic Insight into Rh-Catalyzed C(sp2)–O Bond Cleavage Applied to Cross-Coupling Reaction of Benzofurans with Aryl Grignard Reagents

Selective C–O Bond Reduction and Borylation of Aryl Ethers Catalyzed by a Rhodium–Aluminum Heterobimetallic Complex

(2021) Rin Seki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Anionic Pathway in Nickel‐Catalysed Cross‐Coupling of Aryl Ethers

(2021) Andryj Borys et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel‐Catalyzed Suzuki‐Miyaura Cross‐Coupling Involving C−O Bond Activation

(2021) Aoi Morishige et al.   HELVETICA CHIMICA ACTA

Recent Advances in Continuous‐Flow Enantioselective Catalysis

(2020) Tao Yu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemoselective Cross-Coupling between Two Different and Unactivated C(aryl)–O Bonds Enabled by Chromium Catalysis

(2020) Jinghua Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transformations of Less-Activated Phenols and Phenol Derivatives via C–O Cleavage

(2020) Zihang Qiu et al.   CHEMICAL REVIEWS

Rhodium-Catalyzed Deoxygenation and Borylation of Ketones: A Combined Experimental and Theoretical Investigation

(2020) Lei Tao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of and Structural Insights into Contact Ion Pair and Solvent-Separated Ion Pair Diphenyliridate Complexes

(2020) Takanori Iwasaki et al.   ORGANOMETALLICS

Chemodivergence Between Electrophiles in Cross‐Coupling Reactions

(2020) Emily K Reeves et al.   CHEMISTRY-A EUROPEAN JOURNAL

Harnessing C–O Bonds in Stereoselective Cross-Coupling and Cross-Electrophile Coupling Reactions

(2020) Elizabeth R. Jarvo et al.   SYNLETT

Nickel Carbodicarbene Catalyzes Kumada Cross-Coupling of Aryl Ethers with Grignard Reagents through C-O Bond Activation

(2019) Ram Ambre et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Advances in Transition Metal‐Catalyzed Selective Functionalization of Inert C−O Bonds Assisted by Directing Groups

(2019) Cong Lin et al.   ADVANCED SYNTHESIS & CATALYSIS

Flow Technology for Genesis and Use of (Highly) Reactive Organometallic Reagents

(2019) Marco Colella et al.   CHEMISTRY-A EUROPEAN JOURNAL

Modular Arene Difunctionalization of Unactivated C–O and C–H Bonds by Sequential Chromium-Catalyzed Transformations

(2019) Zhi Rong et al.   ORGANIC LETTERS

Chemodivergent Nickel(0)-Catalyzed Arene C–F Activation with Alkynes: Unprecedented C–F/C–H Double Insertion

(2019) Lorena Capdevila et al.   ACS Catalysis

Copper-Catalyzed Ring-Opening Silylation of Benzofurans with Disilane

(2018) Hayate Saito et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic Insights into the Ni-Catalyzed Reductive Carboxylation of C−O Bonds in Aromatic Esters with CO2 : Understanding Remarkable Ligand and Traceless-Directing-Group Effects

(2018) Yan-Li Han et al.   Chemistry-An Asian Journal

Ni-Catalyzed Dimerization and Hydroperfluoroarylation of 1,3-Dienes

(2018) Takanori Iwasaki et al.   JOURNAL OF ORGANIC CHEMISTRY

Intermediacy of Ni–Ni Species in sp2 C–O Bond Cleavage of Aryl Esters: Relevance in Catalytic C–Si Bond Formation

(2018) Rosie J. Somerville et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-catalyzed coupling reaction of alkyl halides with aryl Grignard reagents in the presence of 1,3-butadiene: mechanistic studies of four-component coupling and competing cross-coupling reactions

(2018) Takanori Iwasaki et al.   Chemical Science

Cross-coupling polycondensation via C–O or C–N bond cleavage

(2018) Ze-Kun Yang et al.   Nature Communications

Less hindered ligands give improved catalysts for the nickel catalysed Grignard cross-coupling of aromatic ethers

(2018) Gavin J. Harkness et al.   Catalysis Science & Technology

Copper-Catalyzed Ring Opening of Benzofurans and Enantioselective Hydroamination Cascade

(2018) Shuli You et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chromium-Catalyzed Regioselective Kumada Arylative Cross-Coupling of C(aryl)–O Bonds with a Traceless Activation Strategy

(2018) Fei Fan et al.   JOURNAL OF ORGANIC CHEMISTRY

Computational Mechanistic Study on the Nickel-Catalyzed C–H/N–H Oxidative Annulation of Aromatic Amides with Alkynes: The Role of the Nickel (0) Ate Complex

(2018) Ken Yamazaki et al.   ORGANOMETALLICS

Combined Theoretical and Experimental Studies of Nickel-Catalyzed Cross-Coupling of Methoxyarenes with Arylboronic Esters via C–O Bond Cleavage

(2017) Martin C. Schwarzer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aromatic Metamorphosis of Dibenzofurans into Triphenylenes Starting with Nickel-Catalyzed Ring-Opening C–O Arylation

(2017) Yuto Kurata et al.   ORGANIC LETTERS

Manganese-Catalyzed Ring Opening of Benzofurans and Its Application to Insertion of Heteroatoms into the C2–O Bond

(2017) Shun Tsuchiya et al.   ORGANIC LETTERS

Revisitation of Organoaluminum Reagents Affords a Versatile Protocol for C–X (X = N, O, F) Bond-Cleavage Cross-Coupling: A Systematic Study

(2017) Hiroyuki Ogawa et al.   ACS Catalysis

Lewis Acid Assisted Nickel-Catalyzed Cross-Coupling of Aryl Methyl Ethers by C−O Bond-Cleaving Alkylation: Prevention of Undesired β-Hydride Elimination

(2016) Xiangqian Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Alkoxy-Alkyl Interconversion with Alkylborane Reagents through C−O Bond Activation of Aryl and Enol Ethers

(2016) Lin Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ester-directed Ru-catalyzed C–O activation/C–C coupling reaction of ortho-methoxy naphthoates with organoboroneopentylates

(2016) Yigang Zhao et al.   CHEMICAL COMMUNICATIONS

Nickel-catalyzed Ring-opening Cross-coupling of Cyclic Alkenyl Ethers with Arylboronic Esters via Carbon–Oxygen Bond Cleavage

(2016) Akimichi Ohtsuki et al.   CHEMISTRY LETTERS

Coupling Reaction of Enol Derivatives with Silyl Ketene Acetals Catalyzed by Gallium Trihalides

(2016) Yoshihiro Nishimoto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nickel-Catalyzed Cross-Coupling of Organolithium Reagents with (Hetero)Aryl Electrophiles

(2016) Dorus Heijnen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cross-Coupling of Organolithium with Ethers or Aryl Ammonium Salts by C−O or C−N Bond Cleavage

(2016) Ze-Kun Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fe-Catalyzed Cross-Coupling Reaction of Vinylic Ethers with Aryl Grignard Reagents

(2016) Takanori Iwasaki et al.   Chemistry-An Asian Journal

Nickel-Catalyzed Alkylative Cross-Coupling of Anisoles with Grignard Reagents via C–O Bond Activation

(2016) Mamoru Tobisu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Boron Insertion into the C2–O Bond of Benzofurans

(2016) Hayate Saito et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Adventure in Sustainable Cross-Coupling of Phenols and Derivatives via Carbon–Oxygen Bond Cleavage

(2016) Huiying Zeng et al.   ACS Catalysis

Flow technology for organometallic-mediated synthesis

(2016) Leonardo Degennaro et al.   Journal of Flow Chemistry

Nickel-Catalyzed C(Aryl)−O Bond Activation/Cross-Coupling Reaction of Carbazoles with Methyl Grignard: Synthesis of Ellipticine

(2016) Sk. Rasheed et al.   Asian Journal of Organic Chemistry

Nickel-Catalyzed Cross-Coupling Reactions of Unreactive Phenolic Electrophiles via C–O Bond Activation

(2016) Mamoru Tobisu et al.   Topics in Current Chemistry

Exploration of Earth-Abundant Transition Metals (Fe, Co, and Ni) as Catalysts in Unreactive Chemical Bond Activations

(2015) Bo Su et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cross-Couplings Using Aryl Ethers via C–O Bond Activation Enabled by Nickel Catalysts

(2015) Mamoru Tobisu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients

(2015) Bernhard Gutmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel catalyzed dealkoxylative Csp2–Csp3 cross coupling reactions – stereospecific synthesis of allylsilanes from enol ethers

(2015) Lin Guo et al.   CHEMICAL COMMUNICATIONS

Nickel-catalyzed Cross-coupling of Anisole Derivatives with Trimethylaluminum through the Cleavage of Carbon–Oxygen Bonds

(2015) Toshifumi Morioka et al.   CHEMISTRY LETTERS

How and Why Does Ni0Promote Smooth Etheric CO Bond Cleavage and CC Bond Formation? A Theoretical Study

(2015) Hiroyuki Ogawa et al.   CHEMISTRY-A EUROPEAN JOURNAL

Indium Tribromide Catalyzed Coupling Reaction of Enol Ethers with Silyl Ketene Imines toward the Synthesis of β,γ-Unsaturated Nitriles

(2015) Yoshihiro Nishimoto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Flow “Fine” Synthesis: High Yielding and Selective Organic Synthesis by Flow Methods

(2015) Shū Kobayashi   Chemistry-An Asian Journal

Regio- and Chemoselective Kumada–Tamao–Corriu Reaction of Aryl Alkyl Ethers Catalyzed by Chromium Under Mild Conditions

(2015) Xuefeng Cong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Cross-Coupling of Anisoles with Alkyl Grignard Reagents via C–O Bond Cleavage

(2015) Mamoru Tobisu et al.   ORGANIC LETTERS

Nickel-Catalyzed Alkynylation of Anisoles via C–O Bond Cleavage

(2015) Mamoru Tobisu et al.   ORGANIC LETTERS

The Use of Gases in Flow Synthesis

(2015) Carl J. Mallia et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Mixed NHC/Phosphine Ni(II) Complexes: Synthesis and Their Applications as Versatile Catalysts for Selective Cross-Couplings of ArMgX with Aryl Chlorides, Fluorides, and Methyl Ethers

(2015) Jie Zhang et al.   ORGANOMETALLICS

Mechanism of Ni-NHC Catalyzed Hydrogenolysis of Aryl Ethers: Roles of the Excess Base

(2015) Liping Xu et al.   ACS Catalysis

Addition-Elimination of Aryldimethylaluminum Reagents to Vinylarenes Promoted by the Addition of a Ketone

(2015) Kazuki Itami et al.   Asian Journal of Organic Chemistry

Metal-Catalyzed Dealkoxylative CarylC sp 3 Cross-Coupling-Replacement of Aromatic Methoxy Groups of Aryl Ethers by Employing a Functionalized Nucleophile

(2014) Matthias Leiendecker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-catalyzed activation of ethers via C–O bond cleavage: a new strategy for molecular diversity

(2014) Josep Cornella et al.   CHEMICAL SOCIETY REVIEWS

Mechanism of Ni N-heterocyclic carbene catalyst for C–O bond hydrogenolysis of diphenyl ether: a density functional study

(2014) Boodsarin Sawatlon et al.   DALTON TRANSACTIONS

Beyond Directed ortho Metalation: Ru-Catalyzed CAr–O Activation/Cross-Coupling Reaction by Amide Chelation

(2014) Yigang Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diarylrhodates as Promising Active Catalysts for the Arylation of Vinyl Ethers with Grignard Reagents

(2014) Takanori Iwasaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Key Mechanistic Features of Ni-Catalyzed C–H/C–O Biaryl Coupling of Azoles and Naphthalen-2-yl Pivalates

(2014) Huiying Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanisms and Origins of Switchable Chemoselectivity of Ni-Catalyzed C(aryl)–O and C(acyl)–O Activation of Aryl Esters with Phosphine Ligands

(2014) Xin Hong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

1,3-Dicyclohexylimidazol-2-ylidene as a Superior Ligand for the Nickel-Catalyzed Cross-Couplings of Aryl and Benzyl Methyl Ethers with Organoboron Reagents

(2014) Mamoru Tobisu et al.   ORGANIC LETTERS

Mixed AggregAte (MAA): A Single Concept for All Dipolar Organometallic Aggregates. 2. Syntheses and Reactivities of Homo/HeteroMAAs

(2013) Florence Mongin et al.   CHEMICAL REVIEWS

Flow chemistry syntheses of natural products

(2013) Julio C. Pastre et al.   CHEMICAL SOCIETY REVIEWS

Carbonylation in microflow: close encounters of CO and reactive species

(2013) Takahide Fukuyama et al.   GREEN CHEMISTRY

Combined Experimental and Theoretical Study on the Reductive Cleavage of Inert C–O Bonds with Silanes: Ruling out a Classical Ni(0)/Ni(II) Catalytic Couple and Evidence for Ni(I) Intermediates

(2013) Josep Cornella et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Programmed Selective sp2 C–O Bond Activation toward Multiarylated Benzenes

(2013) Fei Zhao et al.   ORGANIC LETTERS

Ni-Catalyzed Stereoselective Arylation of Inert C–O bonds at Low Temperatures

(2013) Josep Cornella et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Ortho-Selective C–H Alkenylation of Aromatic Compounds with Alkenyl Esters and Ethers

(2013) Yohei Ogiwara et al.   ORGANOMETALLICS

Gallium Tribromide Catalyzed Coupling Reaction of Alkenyl Ethers with Ketene Silyl Acetals

(2012) Yoshihiro Nishimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New Synthetic Opportunities in Miniaturized Flow Reactors with Inductive Heating

(2012) Andreas Kirschning et al.   CHEMISTRY LETTERS

Aryl Ether as a Negishi Coupling Partner: An Approach for Constructing CC Bonds under Mild Conditions

(2012) Chao Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

The integration of flow reactors into synthetic organic chemistry

(2012) Ian R. Baxendale   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Kumada–Tamao–Corriu Coupling of Heteroaromatic Chlorides and Aryl Ethers Catalyzed by (IPr)Ni(allyl)Cl

(2012) María José Iglesias et al.   ORGANIC LETTERS

Rhodium-Catalyzed Cleavage Reaction of Aryl Methyl Ethers with Thioesters

(2012) Mieko Arisawa et al.   ORGANIC LETTERS

Rhodium-Catalyzed Double 1,4-Addition of Arylboronic Acids to β-Aryloxyacrylates Involving β-Oxygen Elimination

(2011) Takanori Matsuda et al.   ADVANCED SYNTHESIS & CATALYSIS

Rearrangement of 2-Aryloxybenzaldehydes to 2-Hydroxybenzophenones by Rhodium-Catalyzed Cleavage of Aryloxy CO Bonds

(2011) Honghua Rao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alkoxy-Arene Cleavage using Ni Catalysts

(2011) Gerard P. McGlacken et al.   ChemCatChem

Cross-Coupling of Aryl/Alkenyl Ethers with Aryl Grignard Reagents through Nickel-Catalyzed CO Activation

(2011) Lan-Gui Xie et al.   CHEMISTRY-A EUROPEAN JOURNAL

Activation of “Inert” Alkenyl/Aryl CO Bond and Its Application in Cross-Coupling Reactions

(2011) Bi-Jie Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Continuous flow reactors: a perspective

(2011) Charlotte Wiles et al.   GREEN CHEMISTRY

Selective, Nickel-Catalyzed Hydrogenolysis of Aryl Ethers

(2011) A. G. Sergeev et al.   SCIENCE

Space Integration of Reactions: An Approach to Increase the Capability of Organic Synthesis

(2011) Jun-ichi Yoshida et al.   SYNLETT

Exploration of New C−O Electrophiles in Cross-Coupling Reactions

(2010) Da-Gang Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Selective cine Substitution of 1-Arylethenyl Acetates with Arylboron Reagents and a Diene/Rhodium Catalyst

(2010) Jung-Yi Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Cross-Couplings Involving Carbon−Oxygen Bonds

(2010) Brad M. Rosen et al.   CHEMICAL REVIEWS

Green and Sustainable Chemical Synthesis Using Flow Microreactors

(2010) Jun-ichi Yoshida et al.   ChemSusChem

Rhodium-Catalyzed Cross-Coupling of Organoboron Compounds with Vinyl Acetate

(2009) Jung-Yi Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism of Ni-Catalyzed Selective C−O Bond Activation in Cross-Coupling of Aryl Esters

(2009) Zhe Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Cross-Coupling Reaction of Alkenyl Methyl Ethers with Aryl Boronic Esters

(2009) Toshiaki Shimasaki et al.   ORGANIC LETTERS

General and Functional Group-Tolerable Approach to Allenylsilanes by Rhodium-Catalyzed Coupling between Propargylic Carbonates and a Silylboronate

(2009) Hirohisa Ohmiya et al.   ORGANIC LETTERS

Rhodium-Catalyzed Cross-Coupling of Arylboronic Acids Using Vinyl Acetate as the Electrophilic Partner

(2009) Fuk Kwong et al.   SYNLETT

Nickel-Catalyzed Cross-Coupling of Aryl Methyl Ethers with Aryl Boronic Esters

(2008) Mamoru Tobisu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Methylation of arenes via Ni-catalyzed aryl C–O/F activation

(2008) Bing-Tao Guan et al.   CHEMICAL COMMUNICATIONS