A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes
Authors
Keywords
-
Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-06-18
DOI
10.1038/s41467-022-31249-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity
- (2021) Froukje Vanweert et al. INTERNATIONAL JOURNAL OF OBESITY
- Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance
- (2020) Kay H. M. Roumans et al. Nature Communications
- Elevated plasma branched-chain amino acid levels correlate with type 2 diabetes-related metabolic disturbances
- (2020) Froukje Vanweert et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure
- (2019) Golam M. Uddin et al. Cardiovascular Diabetology
- Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance
- (2019) Meiyi Zhou et al. DIABETES
- Therapeutic Effect of Targeting Branched‐Chain Amino Acid Catabolic Flux in Pressure‐Overload Induced Heart Failure
- (2019) Mengping Chen et al. Journal of the American Heart Association
- PP2Cm overexpression alleviates MI/R injury mediated by a BCAA catabolism defect and oxidative stress in diabetic mice
- (2019) Kun Lian et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase
- (2018) Phillip J. White et al. Cell Metabolism
- Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes
- (2018) Adil Mardinoglu et al. EBioMedicine
- Branched Chain Amino Acids in Metabolic Disease
- (2018) Zoltan Arany et al. Current Diabetes Reports
- Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids
- (2018) Michael D. Neinast et al. Cell Metabolism
- A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance
- (2016) Cholsoon Jang et al. NATURE MEDICINE
- The Emerging Role of Branched-Chain Amino Acids in Insulin Resistance and Metabolism
- (2016) Mee-Sup Yoon Nutrients
- Effect of Insulin Sensitizer Therapy on Amino Acids and Their Metabolites
- (2015) Brian A. Irving et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Proton magnetic resonance spectroscopy reveals increased hepatic lipid content after a single high-fat meal with no additional modulation by added protein
- (2014) Lucas Lindeboom et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase
- (2014) Shih-Chia Tso et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sodium phenylbutyrate decreases plasma branched-chain amino acids in patients with urea cycle disorders
- (2014) Lindsay C. Burrage et al. MOLECULAR GENETICS AND METABOLISM
- Branched-chain amino acids in metabolic signalling and insulin resistance
- (2014) Christopher J. Lynch et al. Nature Reviews Endocrinology
- Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity
- (2013) Denise E. Lackey et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Adipose transplant for inborn errors of branched chain amino acid metabolism in mice
- (2013) Heather A. Zimmerman et al. MOLECULAR GENETICS AND METABOLISM
- Relationships between Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes Mellitus
- (2013) Tineke van de Weijer et al. PLoS One
- Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach
- (2012) A. Floegel et al. DIABETES
- Branched-Chain and Aromatic Amino Acids Are Predictors of Insulin Resistance in Young Adults
- (2012) P. Wurtz et al. DIABETES CARE
- Emerging Perspectives on Essential Amino Acid Metabolism in Obesity and the Insulin-Resistant State
- (2012) Sean H. Adams Advances in Nutrition
- Insulin resistance and the metabolism of branched-chain amino acids in humans
- (2011) María M. Adeva et al. AMINO ACIDS
- Metabolite profiles and the risk of developing diabetes
- (2011) Thomas J Wang et al. NATURE MEDICINE
- The role of mitochondria in insulin resistance and type 2 diabetes mellitus
- (2011) Julia Szendroedi et al. Nature Reviews Endocrinology
- Metabolomic Analysis and Visualization Engine for LC−MS Data
- (2010) Eugene Melamud et al. ANALYTICAL CHEMISTRY
- Regulation of hepatic branched-chain α-keto acid dehydrogenase kinase in a rat model for type 2 diabetes mellitus at different stages of the disease
- (2010) Masao Doisaki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals
- (2010) E. Phielix et al. DIABETOLOGIA
- Measurement of longitudinal changes in body composition during weight loss and maintenance in overweight and obese subjects using air-displacement plethysmography in comparison with the deuterium dilution technique
- (2010) G Plasqui et al. INTERNATIONAL JOURNAL OF OBESITY
- A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
- (2009) Christopher B. Newgard et al. Cell Metabolism
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started