Nicotine‑induced miR‑21‑3p promotes chemoresistance in lung cancer by negatively regulating FOXO3a

XPO1 inhibition synergizes with PARP1 inhibition in small cell lung cancer by targeting nuclear transport of FOXO3a

(2021) Jingya Wang et al.   CANCER LETTERS

Vaping and lung cancer – A review of current data and recommendations

(2021) Dara Bracken-Clarke et al.   LUNG CANCER

Lung Cancer 2020

(2020) Brett C. Bade et al.   CLINICS IN CHEST MEDICINE

Pulmonary Toxicity and the Pathophysiology of Electronic Cigarette, or Vaping Product, Use Associated Lung Injury

(2020) Hitendra S. Chand et al.   Frontiers in Pharmacology

Docetaxel-loaded D-α-tocopheryl polyethylene glycol-1000 succinate liposomes improve lung cancer chemotherapy and reverse multidrug resistance

(2020) Na Li et al.   Drug Delivery and Translational Research

Potential effects of nicotine on glioblastoma and chemoradiotherapy: a review

(2019) Diane D. McConnell et al.   Expert Review of Neurotherapeutics

Chemotherapy Resistance Molecular Mechanism in Small Cell Lung Cancer

(2019) Jun Zhou et al.   CURRENT MOLECULAR MEDICINE

LZ-101, a novel derivative of danofloxacin, induces mitochondrial apoptosis by stabilizing FOXO3a via blocking autophagy flux in NSCLC cells

(2019) Yongjian Guo et al.   Cell Death & Disease

Cigarette smoke extract modulates E-Cadherin, Claudin-1 and miR-21 and promotes cancer invasiveness in human colorectal adenocarcinoma cells

(2019) P. Dino et al.   TOXICOLOGY LETTERS

miR-296-3p Negatively Regulated by Nicotine Stimulates Cytoplasmic Translocation of c-Myc via MK2 to Suppress Chemotherapy Resistance

(2018) Xiaojie Deng et al.   MOLECULAR THERAPY

Critical role of FOXO3a in carcinogenesis

(2018) Ying Liu et al.   Molecular Cancer

Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma

(2017) Jong Cheon Joo et al.   Oncotarget

MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ DamageCLINICAL PERSPECTIVE

(2017) Christine M. Willinger et al.   Circulation-Cardiovascular Genetics

MicroRNA expression profiling defines the impact of electronic cigarettes on human airway epithelial cells

(2017) Siva Kumar Solleti et al.   Scientific Reports

Impact of smoking on lung cancer treatment effectiveness: a review

(2016) Adalgisa Condoluci et al.   Future Oncology

MicroRNA-132 and microRNA-223 control positive feedback circuit by regulating FOXO3a in inflammatory bowel disease

(2016) Hye-Youn Kim et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Nicotine Reduces Survival via Augmentation of Paracrine HGF-MET Signaling in the Pancreatic Cancer Microenvironment

(2015) D. Delitto et al.   CLINICAL CANCER RESEARCH

The Regulation and Function of miR-21-FOXO3a-miR-34b/c Signaling in Breast Cancer

(2015) Xiangyan Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nicotine Induces Tumor Growth and Chemoresistance through Activation of the PI3K/Akt/mTOR Pathway in Bladder Cancer

(2015) K. Yuge et al.   MOLECULAR CANCER THERAPEUTICS

Persistence of Smoking-Induced Dysregulation of MiRNA Expression in the Small Airway Epithelium Despite Smoking Cessation

(2015) Guoqing Wang et al.   PLoS One

Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic acetylcholine receptor and STAT3

(2014) Prasun Guha et al.   BREAST CANCER RESEARCH AND TREATMENT

Clinical Significance of Smoking Cessation in Subjects With Cancer: A 30-Year Review

(2014) A. N. Florou et al.   Respiratory Care

Nicotine upregulates microRNA-21 and promotes TGF-β-dependent epithelial-mesenchymal transition of esophageal cancer cells

(2014) Yi Zhang et al.   TUMOR BIOLOGY

AntagomiR-27a Targets FOXO3a in Glioblastoma and Suppresses U87 Cell Growth in Vitro and in Vivo

(2013) Yun-Fei Ge et al.   Asian Pacific Journal of Cancer Prevention

miR-205 Targets PTEN and PHLPP2 to Augment AKT Signaling and Drive Malignant Phenotypes in Non-Small Cell Lung Cancer

(2013) J. Cai et al.   CANCER RESEARCH

Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression

(2013) P. Liu et al.   Clinical & Translational Oncology

De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease

(2013) Hon-Kit Andus Wong et al.   HUMAN MOLECULAR GENETICS

miR-155, a Modulator of FOXO3a Protein Expression, Is Underexpressed and Cannot Be Upregulated by Stimulation of HOZOT, a Line of Multifunctional Treg

(2011) Mayuko Yamamoto et al.   PLoS One

Nicotine Induces Resistance to Chemotherapy in Nasal Epithelial Cancer

(2010) Tianjie Shen et al.   American Journal of Rhinology & Allergy

Toll-like receptor 9-mediated inhibition of apoptosis occurs through suppression of FoxO3a activity and induction of FLIP expression

(2010) Eun-Jung Lim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Biological functions of microRNAs: a review

(2010) Yong Huang et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

PUMA Induction by FoxO3a Mediates the Anticancer Activities of the Broad-Range Kinase Inhibitor UCN-01

(2010) C. Dudgeon et al.   MOLECULAR CANCER THERAPEUTICS

Nicotine Induces Resistance to Chemotherapy by Modulating Mitochondrial Signaling in Lung Cancer

(2008) Jingmei Zhang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

(2008) T. Papagiannakopoulos et al.   CANCER RESEARCH

miR-21: a small multi-faceted RNA

(2008) Anna M. Krichevsky et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE