Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest

The hyper-activation of transcriptional enhancers in breast cancer

(2019) Qing-Lan Li et al.   Clinical Epigenetics

Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment

(2019) Zhongyi Hu et al.   Nature Communications

CUT&Tag for efficient epigenomic profiling of small samples and single cells

(2019) Hatice S. Kaya-Okur et al.   Nature Communications

HBO1(KAT7) does not have an essential role in cell proliferation, DNA replication or histone 4 acetylation in human cells

(2019) Andrew J. Kueh et al.   MOLECULAR AND CELLULAR BIOLOGY

HBO1 is required for the maintenance of leukaemia stem cells

(2019) Laura MacPherson et al.   NATURE

Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response

(2018) Benedetto Daniele Giaimo et al.   NUCLEIC ACIDS RESEARCH

Histone Lysine and Genomic Targets of Histone Acetyltransferases in Mammals

(2018) Anne K. Voss et al.   BIOESSAYS

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

(2018) Jonathan B. Baell et al.   NATURE

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

(2018) Xiaotu Ma et al.   NATURE

The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair

(2016) C Bassi et al.   CELL DEATH AND DIFFERENTIATION

The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation

(2016) Karine Jacquet et al.   MOLECULAR CELL

Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation

(2016) Fei Mo et al.   Nature Chemical Biology

Complete Workflow for Analysis of Histone Post-translational Modifications Using Bottom-up Mass Spectrometry: From Histone Extraction to Data Analysis

(2016) Simone Sidoli et al.   Jove-Journal of Visualized Experiments

WGE: a CRISPR database for genome engineering: Fig. 1.

(2015) Alex Hodgkins et al.   BIOINFORMATICS

Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies

(2015) Yoko Hayashi-Takanaka et al.   CHROMOSOME RESEARCH

High-resolution mapping of H4K16 and H3K23 acetylation reveals conserved and unique distribution patterns inArabidopsisand rice

(2015) Li Lu et al.   Epigenetics

MOZ (MYST3, KAT6A) inhibits senescence via the INK4A-ARF pathway

(2015) B N Sheikh et al.   ONCOGENE

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

(2015) Brandon J. Aubrey et al.   Cell Reports

Cellular senescence and its effector programs

(2014) R. Salama et al.   GENES & DEVELOPMENT

Regulation of RNA polymerase II activation by histone acetylation in single living cells

(2014) Timothy J. Stasevich et al.   NATURE

Histone H3 lysine 4 trimethylation regulates cotranscriptional H2A variant exchange by Tip60 complexes to maximize gene expression

(2014) Thomas Kusch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome

(2014) David A. Orlando et al.   Cell Reports

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

(2013) Hui Yang et al.   CELL

The variant histone H2A.V of Drosophila—three roles, two guises

(2013) Sandro Baldi et al.   CHROMOSOMA

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Role of Tip60 in Human Melanoma Cell Migration, Metastasis, and Patient Survival

(2012) Guangdi Chen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

H2A.Z-dependent crosstalk between enhancer and promoter regulates Cyclin D1 expression

(2012) M Dalvai et al.   ONCOGENE

Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer

(2011) F. Valdes-Mora et al.   GENOME RESEARCH

Recognition of enhancer element–specific histone methylation by TIP60 in transcriptional activation

(2011) Kwang Won Jeong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Individual Lysine Acetylations on the N Terminus ofSaccharomyces cerevisiaeH2A.Z Are Highly but Not Differentially Regulated

(2010) Monika Mehta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HBO1 Is Required for H3K14 Acetylation and Normal Transcriptional Activity during Embryonic Development

(2010) A. J. Kueh et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone variants — ancient wrap artists of the epigenome

(2010) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Moz and Retinoic Acid Coordinately Regulate H3K9 Acetylation, Hox Gene Expression, and Segment Identity

(2009) Anne K. Voss et al.   DEVELOPMENTAL CELL

Homozygous disruption of thetip60gene causes early embryonic lethality

(2009) Yaofei Hu et al.   DEVELOPMENTAL DYNAMICS

An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Identity

(2008) Thomas G. Fazzio et al.   CELL

BRCA1 and Tip60 determine the cellular response to ultraviolet irradiation through distinct pathways

(2008) Dominique Kranz et al.   JOURNAL OF CELL BIOLOGY

Mof (MYST1 or KAT8) Is Essential for Progression of Embryonic Development Past the Blastocyst Stage and Required for Normal Chromatin Architecture

(2008) T. Thomas et al.   MOLECULAR AND CELLULAR BIOLOGY

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS

Transcriptional regulation of chondrogenesis by coactivator Tip60 via chromatin association with Sox9 and Sox5

(2008) Takako Hattori et al.   NUCLEIC ACIDS RESEARCH