The short-chain fatty acid butyrate accelerates vascular calcification via regulation of histone deacetylases and NF-κB signaling

Acetate, a Short-Chain Fatty Acid, Acutely Lowers Heart Rate and Cardiac Contractility along with Blood Pressure

(2021) Brian G Poll et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Medial Arterial Calcification

(2021) Peter Lanzer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-κB (Nuclear Factor κB) Signals

(2020) Xiuli Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

GUT MICROBIOTA AND CARDIOVASCULAR DISEASES

(2020) Gaia Anselmi et al.   Cardiology in Review

Hdac9 inhibits medial artery calcification through down-regulation of Osterix

(2020) Pengcheng He et al.   VASCULAR PHARMACOLOGY

Sodium butyrate protects against lipopolysaccharide-induced liver injury partially via the GPR43/ β-arrestin-2/NF-κB network

(2020) Qian-Jiang Luo et al.   Gastroenterology Report

The Short-Chain Fatty Acid Propionate Protects from Hypertensive Cardiovascular Damage

(2019) Hendrik Bartolomaeus et al.   CIRCULATION

Butyrate protects against high‐fat diet‐induced atherosclerosis via up‐regulating ABCA1 expression in apolipoprotein E‐deficiency mice

(2019) Yu Du et al.   BRITISH JOURNAL OF PHARMACOLOGY

HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype

(2019) Rajeev Malhotra et al.   NATURE GENETICS

Pro- and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells

(2018) Meng Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling

(2018) Jakob Voelkl et al.   JOURNAL OF CLINICAL INVESTIGATION

The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression

(2018) Abdul Malik Tyagi et al.   IMMUNITY

WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression

(2016) Ting Cai et al.   EXPERIMENTAL CELL RESEARCH

MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification

(2016) Duk-Hwa Kwon et al.   Nature Communications

Intestinal Microbiota‐Generated Metabolite Trimethylamine‐N‐Oxide and 5‐Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of Intestinal Microbiota in a COURAGE‐Like Patient Cohort

(2016) Vichai Senthong et al.   Journal of the American Heart Association

BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

(2014) Dongxing Zhu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The contributory role of gut microbiota in cardiovascular disease

(2014) W.H. Wilson Tang et al.   JOURNAL OF CLINICAL INVESTIGATION

Vascular Calcification: An Update on Mechanisms and Challenges in Treatment

(2013) Meiting Wu et al.   CALCIFIED TISSUE INTERNATIONAL

Trichostatin A, an HDAC Class I/II Inhibitor, Promotes Pi-Induced Vascular Calcification Via Up-Regulation of the Expression of Alkaline Phosphatase

(2013) Takuya Azechi et al.   Journal of Atherosclerosis and Thrombosis

Effects of Sodium Butyrate and Its Synthetic Amide Derivative on Liver Inflammation and Glucose Tolerance in an Animal Model of Steatosis Induced by High Fat Diet

(2013) Giuseppina Mattace Raso et al.   PLoS One

Short-Chain Fatty Acids Suppress Lipopolysaccharide-Induced Production of Nitric Oxide and Proinflammatory Cytokines Through Inhibition of NF-κB Pathway in RAW264.7 Cells

(2012) Tengfei Liu et al.   INFLAMMATION

High-phosphate-induced calcification is related to SM22α promoter methylation in vascular smooth muscle cells

(2010) Addy Montes de Oca et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Tumor necrosis factor-α increases alkaline phosphatase expression in vascular smooth muscle cells via MSX2 induction

(2009) Hye-Lim Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sodium butyrate stimulates mineralized nodule formation and osteoprotegerin expression by human osteoblasts

(2008) Tomoko Katono et al.   ARCHIVES OF ORAL BIOLOGY

Vascular Calcification

(2008) Linda L. Demer et al.   CIRCULATION

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS