Physico-chemical properties of aluminum adjuvants in vaccines: Implications for toxicological evaluation

Aluminum Hydroxide And Aluminum Phosphate Adjuvants Elicit A Different Innate Immune Response

(2022) Sietske Kooijman et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Reviewing the association between aluminum adjuvants in the vaccines and autism spectrum disorder

(2021) Alberto Boretti   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Impact of Formulation and Suspension Properties on Redispersion of Aluminum-Adjuvanted Vaccines

(2020) Alex Langford et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The health effects of ultrafine particles

(2020) Dean E. Schraufnagel   EXPERIMENTAL AND MOLECULAR MEDICINE

Toxicological appraisal of the chemical fractions of ambient fine (PM2.5-0.3) and quasi-ultrafine (PM0.3) particles in human bronchial epithelial BEAS-2B cells

(2020) Ghidaa Badran et al.   ENVIRONMENTAL POLLUTION

Distinctive cellular response to aluminum based adjuvants

(2020) Isaac Nies et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Early postnatal injections of whole vaccines compared to placebo controls: Differential behavioural outcomes in mice

(2020) Housam Eidi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Myalgia and chronic fatigue syndrome following immunization: macrophagic myofasciitis and animal studies support linkage to aluminum adjuvant persistency and diffusion in the immune system

(2019) Romain K. Gherardi et al.   AUTOIMMUNITY REVIEWS

Ambient black carbon particles reach the fetal side of human placenta

(2019) Hannelore Bové et al.   Nature Communications

The interaction of aluminium-based adjuvants with THP-1 macrophages in vitro: Implications for cellular survival and systemic translocation

(2019) Emma Shardlow et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Uric acid and the vaccine adjuvant activity of aluminium (oxy)hydroxide nanoparticles

(2018) Sachin G. Thakkar et al.   JOURNAL OF DRUG TARGETING

Critical analysis of reference studies on the toxicokinetics of aluminum-based adjuvants

(2018) Jean-Daniel Masson et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

(2018) Alyona Sukhanova et al.   Nanoscale Research Letters

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

(2018) Alyona Sukhanova et al.   Nanoscale Research Letters

Systems analysis of human vaccine adjuvants

(2018) Ali M. Harandi   SEMINARS IN IMMUNOLOGY

Optimizing the utilization of aluminum adjuvants in vaccines: you might just get what you want

(2018) Harm HogenEsch et al.   npj Vaccines

Nanoparticles and innate immunity: new perspectives on host defence

(2017) Diana Boraschi et al.   SEMINARS IN IMMUNOLOGY

Non-linear dose-response of aluminium hydroxide adjuvant particles: Selective low dose neurotoxicity

(2017) Guillemette Crépeaux et al.   TOXICOLOGY

Adjuvants: Classification,Modus Operandi, and Licensing

(2016) Juliana de Souza Apostólico et al.   Journal of Immunology Research

Insight into the cellular fate and toxicity of aluminium adjuvants used in clinically approved human vaccinations

(2016) Matthew Mold et al.   Scientific Reports

Fluorescent nanodiamonds as a relevant tag for the assessment of alum adjuvant particle biodisposition

(2015) Housam Eidi et al.   BMC Medicine

Highly delayed systemic translocation of aluminum-based adjuvant in CD1 mice following intramuscular injections

(2015) Guillemette Crépeaux et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Translocation of gold nanoparticles across the lung epithelial tissue barrier: Combining in vitro and in silico methods to substitute in vivo experiments

(2015) Gerald Bachler et al.   Particle and Fibre Toxicology

Translocation of positively and negatively charged polystyrene nanoparticles in an in vitro placental model

(2015) Samantha K. Kloet et al.   TOXICOLOGY IN VITRO

New generation adjuvants – From empiricism to rational design

(2015) Derek T. O’Hagan et al.   VACCINE

The effect of particle shape and size on cellular uptake

(2015) M. Zheng et al.   Drug Delivery and Translational Research

Rod-shaped iron oxide nanoparticles are more toxic than sphere-shaped nanoparticles to murine macrophage cells

(2014) Jang Han Lee et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

The impact of size on particulate vaccine adjuvants

(2014) Ruchi R Shah et al.   Nanomedicine

Gold Nanoparticles as a Vaccine Platform: Influence of Size and Shape on Immunological Responses in Vitro and in Vivo

(2013) Kenichi Niikura et al.   ACS Nano

Polymer-Coated Nanoparticles Interacting with Proteins and Cells: Focusing on the Sign of the Net Charge

(2013) Dominik Hühn et al.   ACS Nano

Aluminum hydroxide nanoparticles show a stronger vaccine adjuvant activity than traditional aluminum hydroxide microparticles

(2013) Xinran Li et al.   JOURNAL OF CONTROLLED RELEASE

Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts

(2012) Rosella Coradeghini et al.   TOXICOLOGY LETTERS

Intracellular dynamics of cationic and anionic polystyrene nanoparticles without direct interaction with mitotic spindle and chromosomes

(2011) Yuexian Liu et al.   BIOMATERIALS

Alhydrogel® adjuvant, ultrasonic dispersion and protein binding: A TEM and analytical study

(2011) J. Robin Harris et al.   MICRON

Effects of various physicochemical characteristics on the toxicities of ZnO and TiO2 nanoparticles toward human lung epithelial cells

(2011) I-Lun Hsiao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells

(2010) Sourav Bhattacharjee et al.   Particle and Fibre Toxicology

Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration

(2009) Christopher A. Shaw et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Influence of particle size and antigen binding on effectiveness of aluminum salt adjuvants in a model lysozyme vaccine

(2008) Amber Clausi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Shape Induced Inhibition of Phagocytosis of Polymer Particles

(2008) Julie A. Champion et al.   PHARMACEUTICAL RESEARCH

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA