Microfluidics: a transformational tool for nanomedicine development and production

Designing liposomal adjuvants for the next generation of vaccines

(2016) Yvonne Perrie et al.   ADVANCED DRUG DELIVERY REVIEWS

Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles

(2015) Srinivas Ramishetti et al.   ACS Nano

Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell–Nanoparticle Interaction

(2015) Lu Zhang et al.   ACS Nano

Microfluidic Synthesis of Rigid Nanovesicles for Hydrophilic Reagents Delivery

(2015) Lu Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A highly tumor-targeted nanoparticle of podophyllotoxin penetrated tumor core and regressed multidrug resistant tumors

(2015) Aniruddha Roy et al.   BIOMATERIALS

siRNA Lipid Nanoparticle Potently Silences Clusterin and Delays Progression When Combined with Androgen Receptor Cotargeting in Enzalutamide-Resistant Prostate Cancer

(2015) Y. Yamamoto et al.   CLINICAL CANCER RESEARCH

Microfluidic-controlled manufacture of liposomes for the solubilisation of a poorly water soluble drug

(2015) Elisabeth Kastner et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems

(2015) Alex K. K. Leung et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A strategy for synthesis of lipid nanoparticles using microfluidic devices with a mixer structure

(2015) Masatoshi Maeki et al.   RSC Advances

Development and clinical applications of siRNA-encapsulated lipid nanoparticles in cancer

(2014) Paulo JC Lin et al.   Clinical Lipidology

Docetaxel–carboxymethylcellulose nanoparticles display enhanced anti-tumor activity in murine models of castration-resistant prostate cancer

(2014) Bryan Hoang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

High-throughput manufacturing of size-tuned liposomes by a new microfluidics method using enhanced statistical tools for characterization

(2014) Elisabeth Kastner et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration

(2014) Sam Chen et al.   JOURNAL OF CONTROLLED RELEASE

Microfluidic-Enabled Liposomes Elucidate Size-Dependent Transdermal Transport

(2014) Renee R. Hood et al.   PLoS One

Synthesis of Polymer–Lipid Nanoparticles for Image-Guided Delivery of Dual Modality Therapy

(2013) Aneta J. Mieszawska et al.   BIOCONJUGATE CHEMISTRY

Influence of micro-mixing on the size of liposomes self-assembled from miscible liquid phases

(2013) Sopan M. Phapal et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Preparation of liposomes: A novel application of microengineered membranes–From laboratory scale to large scale

(2013) A. Laouini et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Mass production of highly monodisperse polymeric nanoparticles by parallel flow focusing system

(2013) Xianjie Kang et al.   Microfluidics and Nanofluidics

Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics

(2013) Martin A Maier et al.   MOLECULAR THERAPY

Parallel microfluidic synthesis of size-tunable polymeric nanoparticles using 3D flow focusing towards in vivo study

(2013) Jong-Min Lim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Microfluidic Synthesis of PEG- and Folate-Conjugated Liposomes for One-Step Formation of Targeted Stealth Nanocarriers

(2013) Renee R. Hood et al.   PHARMACEUTICAL RESEARCH

Nanoparticles for Gene Delivery

(2013) Huayu Tian et al.   Small

Liposome: classification, preparation, and applications

(2013) Abolfazl Akbarzadeh et al.   Nanoscale Research Letters

Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain

(2013) Ravi L Rungta et al.   Molecular Therapy-Nucleic Acids

Lipid nanoparticle delivery systems for siRNA-based therapeutics

(2013) C. Wan et al.   Drug Delivery and Translational Research

Advances in Lipid Nanoparticles for siRNA Delivery

(2013) Yuen Tam et al.   Pharmaceutics

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

Production of hyaluronic acid (HA) nanoparticles by a continuous process inside microchannels: Effects of non-solvents, organic phase flow rate, and HA concentration

(2012) Rafaela Costa Souza Bicudo et al.   CHEMICAL ENGINEERING SCIENCE

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

Optimising the self-assembly of siRNA loaded PEG-PCL-lPEI nano-carriers employing different preparation techniques

(2012) Thomas Endres et al.   JOURNAL OF CONTROLLED RELEASE

Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core

(2012) Alex K. K. Leung et al.   Journal of Physical Chemistry C

Rapid Discovery of Potent siRNA-Containing Lipid Nanoparticles Enabled by Controlled Microfluidic Formulation

(2012) Delai Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Microfluidic methods for forming liposomes

(2012) Dirk van Swaay et al.   LAB ON A CHIP

Microfluidic assisted self-assembly of chitosan based nanoparticles as drug delivery agents

(2012) Fatemeh Sadat Majedi et al.   LAB ON A CHIP

Bottom-Up Design and Synthesis of Limit Size Lipid Nanoparticle Systems with Aqueous and Triglyceride Cores Using Millisecond Microfluidic Mixing

(2012) Igor V. Zhigaltsev et al.   LANGMUIR

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

(2012) Nathan M Belliveau et al.   Molecular Therapy-Nucleic Acids

Synthesis of Size-Tunable Polymeric Nanoparticles Enabled by 3D Hydrodynamic Flow Focusing in Single-Layer Microchannels

(2011) Minsoung Rhee et al.   ADVANCED MATERIALS

Medical Applications of Nanoparticles in Biological Imaging, Cell Labeling, Antimicrobial Agents, and Anticancer Nanodrugs

(2011) Ravina Singh et al.   Journal of Biomedical Nanotechnology

Single-Step Assembly of Homogenous Lipid−Polymeric and Lipid−Quantum Dot Nanoparticles Enabled by Microfluidic Rapid Mixing

(2010) Pedro M. Valencia et al.   ACS Nano

Predicting Outcomes in Cervical Cancer: A Kinetic Model of Tumor Regression during Radiation Therapy

(2010) Z. Huang et al.   CANCER RESEARCH

Analysis of lipid nanoparticles by Cryo-EM for characterizing siRNA delivery vehicles

(2010) Randy Crawford et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Hydrocortisone nanosuspensions for ophthalmic delivery: A comparative study between microfluidic nanoprecipitation and wet milling

(2010) Hany S.M. Ali et al.   JOURNAL OF CONTROLLED RELEASE

Transfection Techniques for Neuronal Cells

(2010) D. Karra et al.   JOURNAL OF NEUROSCIENCE

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Size, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cells

(2008) Daniel L.J. Thorek et al.   BIOMATERIALS

Preparation of nanoparticles by continuous-flow microfluidics

(2008) Andreas Jahn et al.   JOURNAL OF NANOPARTICLE RESEARCH

Microfluidic Platform for Controlled Synthesis of Polymeric Nanoparticles

(2008) Rohit Karnik et al.   NANO LETTERS

Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery

(2007) Kishor M. Wasan et al.   NATURE REVIEWS DRUG DISCOVERY