SET protein overexpression contributes to paclitaxel resistance in MCF-7/S cells through PI3K/Akt pathway

Combination of SF1126 and gefitinib induces apoptosis of triple-negative breast cancer cells through the PI3K/AKT–mTOR pathway

(2015) Miao Deng et al.   ANTI-CANCER DRUGS

Structure-Based Lead Optimization and Biological Evaluation of BAX Direct Activators as Novel Potential Anticancer Agents

(2015) Mariano Stornaiuolo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Establishment of Paclitaxel-resistant Breast Cancer Cell Line and Nude Mice Models, and Underlying Multidrug Resistance Mechanisms in Vitro and in Vivo

(2014) Si-Ying Chen et al.   Asian Pacific Journal of Cancer Prevention

Roles of the Bcl-2/Bax Ratio, Caspase-8 and 9 in Resistance of Breast Cancer Cells to Paclitaxel

(2014) Simin Sharifi et al.   Asian Pacific Journal of Cancer Prevention

Lysophosphatidylinositol: a novel link between ABC transporters and G-protein-coupled receptors

(2014) Emily L. Ruban et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Antagonism of SET Using OP449 Enhances the Efficacy of Tyrosine Kinase Inhibitors and Overcomes Drug Resistance in Myeloid Leukemia

(2014) A. Agarwal et al.   CLINICAL CANCER RESEARCH

EGFR as a Potential Target for the Treatment of Pancreatic Cancer: Dilemma and Controversies

(2014) Reza Nedaeinia et al.   CURRENT DRUG TARGETS

Proteomics Identified Overexpression of SET Oncogene Product and Possible Therapeutic Utility of Protein Phosphatase 2A in Alveolar Soft Part Sarcoma

(2014) Daisuke Kubota et al.   JOURNAL OF PROTEOME RESEARCH

Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2

(2014) Jiangxia Cai et al.   PHYTOMEDICINE

MAPK pathway activation leads to Bim loss and histone deacetylase inhibitor resistance: rationale to combine romidepsin with an MEK inhibitor

(2013) A. R. Chakraborty et al.   BLOOD

A leukotriene B4 receptor-2 is associated with paclitaxel resistance in MCF-7/DOX breast cancer cells

(2013) H Kim et al.   BRITISH JOURNAL OF CANCER

Knockdown of cyclophilin A reverses paclitaxel resistance in human endometrial cancer cells via suppression of MAPK kinase pathways

(2013) Zhengyu Li et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Metformin reverses multidrug resistance and epithelial–mesenchymal transition (EMT) via activating AMP-activated protein kinase (AMPK) in human breast cancer cells

(2013) Chen Qu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Proteomic analysis of the proteins that are associated with the resistance to paclitaxel in human breast cancer cells

(2013) Siying Chen et al.   Molecular BioSystems

Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome

(2013) Xu Boqun et al.   International Journal of Endocrinology

A Potential Therapeutic Application of SET/I2PP2A Inhibitor OP449 for Canine T-cell Lymphoma

(2012) Nobuyuki FUJIWARA et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

SET protein accumulates in HNSCC and contributes to cell survival: Antioxidant defense, Akt phosphorylation and AVOs acidification

(2012) Andréia M. Leopoldino et al.   ORAL ONCOLOGY

Phosphorylation of SET Protein at Ser171 by Protein Kinase D2 Diminishes Its Inhibitory Effect on Protein Phosphatase 2A

(2012) Atsushi Irie et al.   PLoS One

Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells

(2012) G M A Ajabnoor et al.   Cell Death & Disease

Effect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells

(2011) Zhiyong Cheng et al.   LEUKEMIA & LYMPHOMA

Targeting SET/I2PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy

(2011) C H Switzer et al.   ONCOGENE