A simple and versatile CRISPR/Cas12a-based immunosensing platform: Towards attomolar level sensitivity for small protein diagnostics

Aptamer-Linked CRISPR/Cas12a-Based Immunoassay

(2021) Hui Li et al.   ANALYTICAL CHEMISTRY

Digital Duplex Homogeneous Immunoassay by Counting Immunocomplex Labeled with Quantum Dots

(2021) Xiaojun Liu et al.   ANALYTICAL CHEMISTRY

MXene Coupled with CRISPR-Cas12a for Analysis of Endotoxin and Bacteria

(2021) Anzhi Sheng et al.   ANALYTICAL CHEMISTRY

Highly Sensitive Immuno-CRISPR Assay for CXCL9 Detection

(2021) Inseon Lee et al.   ANALYTICAL CHEMISTRY

Study on Factors Affecting the Performance of a CRISPR/Cas-Assisted New Immunoassay: Detection of Salivary Insulin as an Example

(2021) Xiaoting Lin et al.   Frontiers in Bioengineering and Biotechnology

Rapid and sensitive exosome detection with CRISPR/Cas12a

(2020) Xianxian Zhao et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Surpassing the detection limit and accuracy of the electrochemical DNA sensor through the application of CRISPR Cas systems

(2020) Wei Xu et al.   BIOSENSORS & BIOELECTRONICS

Single-Step, Salt-Aging-Free, and Thiol-Free Freezing Construction of AuNP-Based Bioprobes for Advancing CRISPR-Based Diagnostics

(2020) Menglu Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ultrabright Fluorescence Readout of an Inkjet-Printed Immunoassay Using Plasmonic Nanogap Cavities

(2020) Daniela F. Cruz et al.   NANO LETTERS

Applying CRISPR-Cas12a as a Signal Amplifier to Construct Biosensors for Non-DNA Targets in Ultralow Concentrations

(2020) Junjie Li et al.   ACS Sensors

An ultrasensitive and specific point-of-care CRISPR/Cas12 based lateral flow biosensor for the rapid detection of nucleic acids

(2020) Omar Mukama et al.   BIOSENSORS & BIOELECTRONICS

Point-of-care CRISPR/Cas nucleic acid detection: Recent advances, challenges and opportunities

(2020) Jeanne E. van Dongen et al.   BIOSENSORS & BIOELECTRONICS

Clustered Regularly Interspaced Short Palindromic Repeats-Mediated Surface-Enhanced Raman Scattering Assay for Multidrug-Resistant Bacteria

(2020) Hongki Kim et al.   ACS Nano

CRISPR/Cas Systems towards Next-Generation Biosensing

(2019) Yi Li et al.   TRENDS IN BIOTECHNOLOGY

Exploring the Trans-Cleavage Activity of CRISPR-Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor

(2019) Yifan Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

(2019) Mindong Liang et al.   Nature Communications

CRISPR/Cas13a Signal Amplification Linked Immunosorbent Assay for Femtomolar Protein Detection

(2019) Qian Chen et al.   ANALYTICAL CHEMISTRY

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic-Acid Targets

(2019) Ying Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

(2018) Shi-Yuan Li et al.   CELL RESEARCH

Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of Parkinson’s disease

(2018) M.N. Karpenko et al.   CELLULAR IMMUNOLOGY

Antibodies in the Diagnosis, Prognosis, and Prediction of Psychotic Disorders

(2018) Thomas A Pollak et al.   SCHIZOPHRENIA BULLETIN

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Next-generation diagnostics with CRISPR

(2018) Daniel S. Chertow   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Pathogen detection in the CRISPR–Cas era

(2018) Dipali G. Sashital   Genome Medicine

CRISPR-Cas12a-assisted nucleic acid detection

(2018) Shi-Yuan Li et al.   Cell Discovery

Challenges and Solutions in Developing Ultrasensitive Biosensors

(2018) Yanfang Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NP220 mediates silencing of unintegrated retroviral DNA

(2018) Yiping Zhu et al.   NATURE

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

(2018) Lucas B. Harrington et al.   SCIENCE

Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+]i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro

(2018) Adel Alhazzani et al.   Cells

Targeted chromatin ligation, a robust epigenetic profiling technique for small cell numbers

(2017) Mark A. Zarnegar et al.   NUCLEIC ACIDS RESEARCH

Nucleic acid detection with CRISPR-Cas13a/C2c2

(2017) Jonathan S. Gootenberg et al.   SCIENCE

Decoration of Reduced Graphene Oxide Nanosheets with Aryldiazonium Salts and Gold Nanoparticles toward a Label-Free Amperometric Immunosensor for Detecting Cytokine Tumor Necrosis Factor-α in Live Cells

(2016) Meng Qi et al.   ANALYTICAL CHEMISTRY

Aptamers, antibody scFv, and antibody Fab' fragments: An overview and comparison of three of the most versatile biosensor biorecognition elements

(2016) Victor Crivianu-Gaita et al.   BIOSENSORS & BIOELECTRONICS

Applications of CRISPR technologies in research and beyond

(2016) Rodolphe Barrangou et al.   NATURE BIOTECHNOLOGY

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

(2016) Omar O. Abudayyeh et al.   SCIENCE

A microfluidic device for the automated electrical readout of low-density glass-slide microarrays

(2015) María Díaz-González et al.   BIOSENSORS & BIOELECTRONICS

Measuring affinity constants of 1450 monoclonal antibodies to peptide targets with a microarray-based label-free assay platform

(2015) J.P. Landry et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Genome-editing revolution: My whirlwind year with CRISPR

(2015) Jennifer Doudna   NATURE

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

(2014) Randall J. Platt et al.   CELL

Cerebrospinal fluid and serum cytokine profiling to detect immune control of infectious and inflammatory neurological and psychiatric diseases

(2014) Horst-Guenter Maxeiner et al.   CYTOKINE

CRISPR/Cas9 for genome editing: progress, implications and challenges

(2014) F. Zhang et al.   HUMAN MOLECULAR GENETICS

Origins of specificity and affinity in antibody–protein interactions

(2014) Hung-Pin Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrochemical Immunosensors for Detection of Cancer Protein Biomarkers

(2012) Bhaskara V. Chikkaveeraiah et al.   ACS Nano

Fluorescent-labeled antibodies: Balancing functionality and degree of labeling

(2010) Shaleen Vira et al.   ANALYTICAL BIOCHEMISTRY