Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function
Published 2022 View Full Article
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Title
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function
Authors
Keywords
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Journal
SCIENCE
Volume 376, Issue 6600, Pages 1471-1476
Publisher
American Association for the Advancement of Science (AAAS)
Online
2022-06-24
DOI
10.1126/science.abf8980
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- (2021) Sugako Oka et al. Scientific Reports
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- (2020) Daniel Schniertshauer et al. DNA REPAIR
- Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome
- (2020) Shrabasti Roychoudhury et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2020) Bishoy M. F. Hanna et al. Biomolecules
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- (2020) Torkild Visnes et al. NUCLEIC ACIDS RESEARCH
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- (2019) Maurice Michel et al. ACS Omega
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- (2018) Beverly A. Baptiste et al. FREE RADICAL BIOLOGY AND MEDICINE
- Potent and Selective Inhibitors of 8-Oxoguanine DNA Glycosylase
- (2018) Yu-ki Tahara et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Targeting DNA repair with PNKP inhibition sensitizes radioresistant prostate cancer cells to high LET radiation
- (2018) Pallavi Srivastava et al. PLoS One
- Targeting BER enzymes in cancer therapy
- (2018) Torkild Visnes et al. DNA REPAIR
- The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue
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- (2018) Zhimin Huang et al. Nature Chemical Biology
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- (2016) Weijie You et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- The cellular thermal shift assay for evaluating drug target interactions in cells
- (2014) Rozbeh Jafari et al. Nature Protocols
- Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
- (2013) B. P. Hubbard et al. SCIENCE
- Activation of Ras Signaling Pathway by 8-Oxoguanine DNA Glycosylase Bound to Its Excision Product, 8-Oxoguanine
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- An efficient route to 1-aminoisoquinolines via AgOTf-catalyzed reaction of 2-alkynylbenzaldoxime with amine
- (2011) Danqing Zheng et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Editing of misaligned 3'-termini by an intrinsic 3'-5' exonuclease activity residing in the PHP domain of a family X DNA polymerase
- (2008) B. Banos et al. NUCLEIC ACIDS RESEARCH
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