A quantification method of somatic mutations in normal tissues and their accumulation in pediatric patients with chemotherapy

Somatic mutation landscapes at single-molecule resolution

(2021) Federico Abascal et al.   NATURE

Mapping genomic and epigenomic evolution in cancer ecosystems

(2021) Toshikazu Ushijima et al.   SCIENCE

The evolution of hematopoietic cells under cancer therapy

(2021) Oriol Pich et al.   Nature Communications

Tobacco smoking and somatic mutations in human bronchial epithelium

(2020) Kenichi Yoshida et al.   NATURE

Macroscopic somatic clonal expansion in morphologically normal human urothelium

(2020) Ruoyan Li et al.   SCIENCE

A Compendium of Mutational Signatures of Environmental Agents

(2019) Jill E. Kucab et al.   CELL

Genome-wide somatic mutation analysis via Hawk-Seq™ reveals mutation profiles associated with chemical mutagens

(2019) Shoji Matsumura et al.   ARCHIVES OF TOXICOLOGY

Enhancing the accuracy of next-generation sequencing for detecting rare and subclonal mutations

(2018) Jesse J. Salk et al.   NATURE REVIEWS GENETICS

Detecting Rare Mutations and DNA Damage with Sequencing-Based Methods

(2018) Daniel B. Sloan et al.   TRENDS IN BIOTECHNOLOGY

Somatic mutagenesis in satellite cells associates with human skeletal muscle aging

(2018) Irene Franco et al.   Nature Communications

Duplex Proximity Sequencing (Pro-Seq): A method to improve DNA sequencing accuracy without the cost of molecular barcoding redundancy

(2018) Joel Pel et al.   PLoS One

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

(2018) Akira Yokoyama et al.   NATURE

COSMIC: the Catalogue Of Somatic Mutations In Cancer

(2018) John G Tate et al.   NUCLEIC ACIDS RESEARCH

Somatic mutant clones colonize the human esophagus with age

(2018) Iñigo Martincorena et al.   SCIENCE

Tissue-specific mutation accumulation in human adult stem cells during life

(2016) Francis Blokzijl et al.   NATURE

Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing

(2016) Margaret L. Hoang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesis

(2014) M R Corces-Zimmerman et al.   LEUKEMIA

Detecting ultralow-frequency mutations by Duplex Sequencing

(2014) Scott R Kennedy et al.   Nature Protocols

Characterization of the Mutagenic Spectrum of 4-Nitroquinoline 1-Oxide (4-NQO) in Aspergillus nidulans by Whole Genome Sequencing

(2014) Damien J. Downes et al.   G3-Genes Genomes Genetics

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Therapy-Related Myelodysplasia and Acute Myeloid Leukemia

(2013) Smita Bhatia   SEMINARS IN ONCOLOGY

Detection of ultra-rare mutations by next-generation sequencing

(2012) M. W. Schmitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A reduced representation approach to population genetic analyses and applications to human evolution

(2011) F. Luca et al.   GENOME RESEARCH

Long-term Risks of Subsequent Primary Neoplasms Among Survivors of Childhood Cancer

(2011) Raoul C. Reulen   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

SNP discovery and allele frequency estimation by deep sequencing of reduced representation libraries

(2008) Curtis P Van Tassell et al.   NATURE METHODS