Insulin-Like Growth Factor-1–Mediated DNA Repair in Irradiated Salivary Glands Is Sirtuin-1 Dependent

Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation

(2016) Y. Marmary et al.   CANCER RESEARCH

Repair Pathway Choices and Consequences at the Double-Strand Break

(2016) Raphael Ceccaldi et al.   TRENDS IN CELL BIOLOGY

The same, only different - DNA damage checkpoints and their reversal throughout the cell cycle

(2015) I. A. Shaltiel et al.   JOURNAL OF CELL SCIENCE

Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence

(2014) Duc Tran et al.   AGING CELL

Inhibiting Tyrosine Phosphorylation of Protein Kinase Cδ (PKCδ) Protects the Salivary Gland from Radiation Damage

(2014) Sten M. Wie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Label-Retaining Cells in the Adult Murine Salivary Glands Possess Characteristics of Adult Progenitor Cells

(2014) Alejandro M. Chibly et al.   PLoS One

Autophagy Correlates with Maintenance of Salivary Gland Function Following Radiation

(2014) Maria Morgan-Bathke et al.   Scientific Reports

Impact of targeting insulin-like growth factor signaling in head and neck cancers

(2013) Kirsten H. Limesand et al.   GROWTH HORMONE & IGF RESEARCH

Nanoparticle-mediated Gene Silencing Confers Radioprotection to Salivary Glands In Vivo

(2013) Szilvia Arany et al.   MOLECULAR THERAPY

Prevention of Radiation-Induced Salivary Gland Dysfunction Utilizing a CDK Inhibitor in a Mouse Model

(2012) Katie L. Martin et al.   PLoS One

The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy

(2011) N. R. Sundaresan et al.   Science Signaling

Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes

(2010) F Al-Ejeh et al.   ONCOGENE

IGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoter

(2010) G C Mitchell et al.   Cell Death & Disease

Radiation-Induced Salivary Gland Dysfunction Results From p53-Dependent Apoptosis

(2009) Jennifer L. Avila et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Ionizing Radiation Induces Cellular Senescence of Articular Chondrocytes via Negative Regulation of SIRT1 by p38 Kinase

(2009) Eun-Hee Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overall Cdk activity modulates the DNA damage response in mammalian cells

(2009) Antonio Cerqueira et al.   JOURNAL OF CELL BIOLOGY

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Suppression of Radiation-Induced Salivary Gland Dysfunction by IGF-1

(2009) Kirsten H. Limesand et al.   PLoS One

SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons

(2008) Ying Li et al.   Cell Metabolism

Early events in the mammalian response to DNA double-strand breaks

(2008) L. C. Riches et al.   MUTAGENESIS

The ups and downs of SIRT1

(2008) Hye-Sook Kwon et al.   TRENDS IN BIOCHEMICAL SCIENCES

AsSIRTing the DNA damage response

(2008) Myriam Gorospe et al.   TRENDS IN CELL BIOLOGY

p21 Inhibits Cdk1 in the Absence of Cdk2 to Maintain the G1/S Phase DNA Damage Checkpoint

(2007) Ande Satyanarayana et al.   MOLECULAR BIOLOGY OF THE CELL