YAP induces an oncogenic transcriptional program through TET1-mediated epigenetic remodeling in liver growth and tumorigenesis
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
YAP induces an oncogenic transcriptional program through TET1-mediated epigenetic remodeling in liver growth and tumorigenesis
Authors
Keywords
-
Journal
NATURE GENETICS
Volume 54, Issue 8, Pages 1202-1213
Publisher
Springer Science and Business Media LLC
Online
2022-07-15
DOI
10.1038/s41588-022-01119-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- TET1 upregulation drives cancer cell growth through aberrant enhancer hydroxymethylation of HMGA2 in hepatocellular carcinoma
- (2021) Kiyokazu Shirai et al. CANCER SCIENCE
- WWTR1(TAZ)-CAMTA1 reprograms endothelial cells to drive epithelioid hemangioendothelioma
- (2021) Jordan H. Driskill et al. GENES & DEVELOPMENT
- TFmotifView: a webserver for the visualization of transcription factor motifs in genomic regions
- (2020) Clémentine Leporcq et al. NUCLEIC ACIDS RESEARCH
- TET1 promotes malignant progression of cholangiocarcinoma with IDH1 wild‐type
- (2020) Xuewei Bai et al. HEPATOLOGY
- p53-suppressed oncogene TET1 prevents cellular aging in lung cancer
- (2019) Piotr T. Filipczak et al. CANCER RESEARCH
- Lgr5+ stem/progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool
- (2019) Nicole Prior et al. DEVELOPMENT
- GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
- (2019) Zefang Tang et al. NUCLEIC ACIDS RESEARCH
- The Hippo Signaling Pathway in Development and Disease
- (2019) Yonggang Zheng et al. DEVELOPMENTAL CELL
- The diverse roles of DNA methylation in mammalian development and disease
- (2019) Maxim V. C. Greenberg et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration
- (2019) Luigi Aloia et al. NATURE CELL BIOLOGY
- TET1-mediated hypomethylation activates oncogenic signaling in triple-negative breast cancer
- (2018) Charly Ryan Good et al. CANCER RESEARCH
- Oncogenic Signaling Pathways in The Cancer Genome Atlas
- (2018) Francisco Sanchez-Vega et al. CELL
- Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4
- (2018) Francesca Zanconato et al. NATURE MEDICINE
- Sin3A recruits Tet1 to the PAH1 domain via a highly conserved Sin3-Interaction Domain
- (2018) Aditya Chandru et al. Scientific Reports
- iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data
- (2018) Steven Xijin Ge et al. BMC BIOINFORMATICS
- The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ
- (2018) Lei Chang et al. NATURE
- Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
- (2018) Iván M. Moya et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- NUAK2 is a critical YAP target in liver cancer
- (2018) Wei-Chien Yuan et al. Nature Communications
- Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis
- (2017) Sachin H. Patel et al. GASTROENTEROLOGY
- TET-mediated active DNA demethylation: mechanism, function and beyond
- (2017) Xiaoji Wu et al. NATURE REVIEWS GENETICS
- The Encyclopedia of DNA elements (ENCODE): data portal update
- (2017) Carrie A Davis et al. NUCLEIC ACIDS RESEARCH
- GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
- (2017) Zefang Tang et al. NUCLEIC ACIDS RESEARCH
- TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo
- (2017) Shilpy Joshi et al. PLoS Genetics
- YAP/TAZ at the Roots of Cancer
- (2016) Francesca Zanconato et al. CANCER CELL
- Role of TET enzymes in DNA methylation, development, and cancer
- (2016) Kasper Dindler Rasmussen et al. GENES & DEVELOPMENT
- Isoform Switch of TET1 Regulates DNA Demethylation and Mouse Development
- (2016) Wenhao Zhang et al. MOLECULAR CELL
- The molecular hallmarks of epigenetic control
- (2016) C. David Allis et al. NATURE REVIEWS GENETICS
- Histone Modifications and Cancer
- (2016) James E. Audia et al. Cold Spring Harbor Perspectives in Biology
- Epigenetic Determinants of Cancer
- (2016) Stephen B. Baylin et al. Cold Spring Harbor Perspectives in Biology
- Tead and AP1 Coordinate Transcription and Motility
- (2016) Xiangfan Liu et al. Cell Reports
- ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization
- (2015) Guangchuang Yu et al. BIOINFORMATICS
- Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
- (2015) Fa-Xing Yu et al. CELL
- Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP
- (2015) Qian Chen et al. GENES & DEVELOPMENT
- Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer
- (2015) Dean Yimlamai et al. JOURNAL OF HEPATOLOGY
- Dynamic Switching of Active Promoter and Enhancer Domains Regulates Tet1 and Tet2 Expression during Cell State Transitions between Pluripotency and Differentiation
- (2015) Abhishek Sohni et al. MOLECULAR AND CELLULAR BIOLOGY
- Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
- (2015) Francesca Zanconato et al. NATURE CELL BIOLOGY
- YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers
- (2015) Claudia Stein et al. PLoS Genetics
- Hippo Pathway Activity Influences Liver Cell Fate
- (2014) Dean Yimlamai et al. CELL
- TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells
- (2014) C. Jin et al. NUCLEIC ACIDS RESEARCH
- Yorkie Promotes Transcription by Recruiting a Histone Methyltransferase Complex
- (2014) Hyangyee Oh et al. Cell Reports
- 5-Hydroxymethylcytosine Plays a Critical Role in Glioblastomagenesis by Recruiting the CHTOP-Methylosome Complex
- (2014) Hiroki Takai et al. Cell Reports
- The Hippo Transducer TAZ Interacts with the SWI/SNF Complex to Regulate Breast Epithelial Lineage Commitment
- (2014) Adam Skibinski et al. Cell Reports
- The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6
- (2014) Yun Qing et al. eLife
- Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition
- (2013) Run-Rui Zhang et al. Cell Stem Cell
- TET enzymes, TDG and the dynamics of DNA demethylation
- (2013) Rahul M. Kohli et al. NATURE
- Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
- (2013) Myunggon Ko et al. NATURE
- TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
- (2013) William A. Pastor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- TET1 plays an essential oncogenic role in MLL-rearranged leukemia
- (2013) H. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic Reprogramming in Cancer
- (2013) M. L. Suva et al. SCIENCE
- Genome-wide Association of Yorkie with Chromatin and Chromatin-Remodeling Complexes
- (2013) Hyangyee Oh et al. Cell Reports
- Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells
- (2012) Hsing-Chen Tsai et al. CANCER CELL
- Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome
- (2012) Miao Yu et al. CELL
- Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA
- (2012) Jeremy M Simon et al. Nature Protocols
- A complete workflow for the analysis of full-size ChIP-seq (and similar) data sets using peak-motifs
- (2012) Morgane Thomas-Chollier et al. Nature Protocols
- Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment
- (2012) P. Home et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Signals and Combinatorial Functions of Histone Modifications
- (2011) Tamaki Suganuma et al. Annual Review of Biochemistry
- Tet1 Is Dispensable for Maintaining Pluripotency and Its Loss Is Compatible with Embryonic and Postnatal Development
- (2011) Meelad M. Dawlaty et al. Cell Stem Cell
- Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells
- (2011) Kian Peng Koh et al. Cell Stem Cell
- Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
- (2011) Gabriella Ficz et al. NATURE
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- Hippo signaling: growth control and beyond
- (2010) G. Halder et al. DEVELOPMENT
- The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
- (2010) Nailing Zhang et al. DEVELOPMENTAL CELL
- Kibra Is a Regulator of the Salvador/Warts/Hippo Signaling Network
- (2010) Alice Genevet et al. DEVELOPMENTAL CELL
- Structural insights into the YAP and TEAD complex
- (2010) Z. Li et al. GENES & DEVELOPMENT
- Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
- (2010) Myunggon Ko et al. NATURE
- Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
- (2010) Shinsuke Ito et al. NATURE
- Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
- (2010) Johannes Zuber et al. NATURE BIOTECHNOLOGY
- GREAT improves functional interpretation of cis-regulatory regions
- (2010) Cory Y McLean et al. NATURE BIOTECHNOLOGY
- The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing
- (2010) Yun Huang et al. PLoS One
- Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene
- (2009) Dawang Zhou et al. CANCER CELL
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- TEAD mediates YAP-dependent gene induction and growth control
- (2008) B. Zhao et al. GENES & DEVELOPMENT
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search